ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

CO2 Angiography Provides a Safe Alternative to Iodinated Contrast Agents in the Diagnosis and Endovascular Treatment of Transplant Renal Artery Stenosis

B. Gelb,1 N. Cayne,2 J. Benstein,3 G. Morgan,1 K. Bortecen,1 M. Hamshow,1 L. Teperman.1

1Transplant Surgery, NYU Langone Medical Center, NY, NY
2Vascular Surgery, NYU, NY
3Transplant Nephrology, NYU, NY.

Meeting: 2015 American Transplant Congress

Abstract number: B234

Keywords: Kidney transplantation, Renal artery stenosis

Session Information

Date: Sunday, May 3, 2015

Session Name: Poster Session B: Radiology/Renal Artery Stenosis

Session Time: 5:30pm-6:30pm

 Presentation Time: 5:30pm-6:30pm

Location: Exhibit Hall E

Related Abstracts
  • Re-Evaluate the Transplant Renal Artery Stenosis After Renal Transplantation Based On New Unenhanced Magnetic Resonance Angiography By Using Spatial Labeling With Multiple Inversion Pulses
  • Clinical and Radiological Predictors of Transplant Renal Artery Stenosis (TRAS)

Background: Transplant Renal Artery Stenosis (TRAS) is a recognized complication resulting in graft dysfunction and post-transplant hypertension. Non-nephrotoxic imaging modalities such as ultrasonography are effective diagnostically, though definitive intervention historically requires vascular angiography with contrast agents. This presents a clinical challenge due to potential nephrotoxic effects of iodinated contrast agents in the setting of pre-existing graft dysfunction. CO2 angiography, which lacks nephrotoxic properties, is a potential alternative agent in the treatment of transplant renal artery stenosis.

Methods: Patients with suspected transplant renal artery stenosis diagnosed by non-invasive imaging modalities (ultrasonography, MRI, or both) underwent CO2 angiography in a vascular hybrid suite with definitive treatment with angioplasty alone, or angioplasty and drug-eluting stent placement. Clinical findings, Creatinine at baseline, time of procedure, early post procedure, and long-term nadir were reviewed.

Results: Of 113 transplants, 6 patients were identified to have potential TRAS who underwent CO2 angiography. 5 of 6 patients had stenosis of the proximal renal artery adjacent to the anastomosis, and 1 patient had an intimal dissection of the native external iliac artery with a web overlying the ostium of the renal artery. Of the 5 patients with TRAS, 4 were cadaveric grafts and 1 was a living donor. Diagnosis was made 3-7 months post-transplant. 3 of 5 presented with rising Cr, worsening htn, and peripheral edema. 1 presented with rising Cr and htn, and 1 presented with hypertensive emergency as the sole symptom. 2 of 5 patients were treated with PTA alone; 1 restenosed in the first month, and 1 remains with a baseline Cr at 8 months. 3 of 5 were treated initially with PTA and drug-eluting stent placement, as well the pt with restenosis. All 4 maintain a baseline Cr. Of the 6 procedures for treatment of TRAS, 5 demonstrated rapid improvement in renal function within 48 hours of intervention. The patient with intimal dissection and web underwent PTA to alleviate the obstructive component.

Conclusion: CO2 angiography is a safe, nephrotoxic-free contrast modality for the endovascular management of TRAS. Best patency rates are with PTA/stent placement.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Gelb B, Cayne N, Benstein J, Morgan G, Bortecen K, Hamshow M, Teperman L. CO2 Angiography Provides a Safe Alternative to Iodinated Contrast Agents in the Diagnosis and Endovascular Treatment of Transplant Renal Artery Stenosis [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/co2-angiography-provides-a-safe-alternative-to-iodinated-contrast-agents-in-the-diagnosis-and-endovascular-treatment-of-transplant-renal-artery-stenosis/. Accessed December 12, 2019.

« Back to 2015 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Penis Transplantation: First U.S. Experience.
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Tacrolimus Dose and Trough Blood Levels in a US Liver Transplant Population
  • Penis Transplantation: First U.S. Experience.
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Tacrolimus Dose and Trough Blood Levels in a US Liver Transplant Population
  • Penis Transplantation: First U.S. Experience.

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2019 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

wiley-new-logo

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.