Clinical Outcomes in Older Kidney Transplant Recipients. A Single Center Experience.
Montefiore Medical Center Transplant Center, Albert Einstein College of Medicine, NY
Meeting: 2017 American Transplant Congress
Abstract number: C151
Keywords: Graft failure
Session Information
Session Name: Poster Session C: Kidney Complications III
Session Type: Poster Session
Date: Monday, May 1, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Background: We aimed to investigate the clinical outcomes of kidney transplant recipients 65 years and older.
Methods: Between 1/2009 and 12/2014, 687 patients underwent a kidney transplantation at our institution. Of those, 132 were older than 65.
Results: There was no difference between the 2 groups in terms of gender, race, thymoglobulin induction, rates of acute rejection, BK and CMV viremia. Older recipients were more likely to receive a deceased donor transplant, and donors were of higher KPDI. Older recipients had higher rates of malignancy. Interestingly, we did not observe a difference in graft and patient survival between the 2 groups.
Conclusion: Despite a higher rate of malignancy, well selected older transplant recipients have similar patient survival and graft survival rates when compared to younger recipients.
| Age ≥65
N=132 |
Age<65
N=555 |
p | |
| Age, mean ± SD | 69.2 ± 3.1 | 48.9±11.5 | 0.0001 |
| Sex, % male | 62 | 58 | 0.4 |
| Race, % AA | 40 | 41 | 0.8 |
| Type of transplant, % deceased-donor | 91 | 73 | 0.0001 |
| KDPI, mean±SD | 72.3±22.9 | 58±27.3 | 0.0001 |
| Induction, % thymoglobulin | 50 | 58 | 0.19 |
| Class I PRA, mean±SD | 12.9±25.8 | 18.6±30.9 | 0.05 |
| Class II PRA, mean ± SD | 12.1±26.2 | 17.4±30 | 0.06 |
| pretransplant DSA | 11.8% | 17% | 0.1 |
| De novo DSA | 15.9% | 20% | 0.27 |
| Acute rejection, % | 6 | 13 | 0.06 |
| CMV viremia | 8 | 10 | 0.51 |
| BKV viremia | 21 | 19 | 0.63 |
| Malignancy | 13 | 3.7 | 0.0001 |
| Fungal infection | 4.7 | 1.7 | 0.1 |
| Creatinine at last F/U, mean±SD | 1.53±0.74 | 1.58±1.08 | 0.61 |
CITATION INFORMATION: Kamal L, Hayde N, Bedi P, Lubetzky M, Ajaimy M, DeBoccardo G, Akalin E. Clinical Outcomes in Older Kidney Transplant Recipients. A Single Center Experience. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Kamal L, Hayde N, Bedi P, Lubetzky M, Ajaimy M, DeBoccardo G, Akalin E. Clinical Outcomes in Older Kidney Transplant Recipients. A Single Center Experience. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/clinical-outcomes-in-older-kidney-transplant-recipients-a-single-center-experience/. Accessed November 25, 2024.« Back to 2017 American Transplant Congress