Session Name: Liver: MELD, Allocation and Donor Issues (DCD/ECD)
Session Date & Time: None. Available on demand.
*Purpose: LT has the limitation of lack of donors compared to those waiting for a transplant. Depending on the recipient’s condition, even liver grafts with poor conditions may need to be transplanted. This study was conducted to analyze the prognosis after liver transplantation that abandoned transplantation due to poor graft conditions at the preceding centers.
*Methods: From January 2010 to September 2020, Deceased-donor liver transplantation (DDLT) was performed in 160 patients in our center. Among them, 121 patients (allocated group) were preferentially allocated to our center by KONOS and the remaining 39 patients (24.4%, abandoned group) received liver grafts that were abandoned by other transplant centers due to poor organ conditions. To compare and analyze the clinical prognosis of the allocated group and the abandoned group, various perioperative factors and postoperative outcomes were evaluated.
*Results: The average ages of the allocated and abandoned groups were 52.8 and 51.3 years, respectively (p=0.38). The preoperative Model for End-stage Liver Disease (MELD) score was 27.0 ± 10.4 in the allocation group and 27.0 ±11.8 in the abandoned group (p=0.99). There was no difference between the two groups in operation time (p=0.06) and intraoperative PRC transfusion (p=0.90). There was no difference between the two groups in hospital stay (p=0.26). The period of admission to the ICU after DDLT was 12.4 days in the abandoned group, which was longer than 8.7 days in the allocated group (p=0.04). In-hospital mortality occurred in 15 patients in the allocated group, and 5 patients in the abandoned group, so there was no difference between the two groups (p=0.47). The 5-year survival rate was 73.8% in the allocated group and 72.2% in the abandoned group, with no difference between the two groups (p=0.67)
*Conclusions: Even if the graft that was abandoned due to poor condition, good results can be obtained if the transplant is carried out according to the recipient state. And as a result, it is expected that the discarded graft can be reduced.
To cite this abstract in AMA style:Choi H, Na G. Clinical Analysis of the Prognosis After Receiving a Liver Graft That Abandoned Transplantation Due to Poor Graft Conditions in the Centers Allocated as a Priority [abstract]. Am J Transplant. 2021; 21 (suppl 3). https://atcmeetingabstracts.com/abstract/clinical-analysis-of-the-prognosis-after-receiving-a-liver-graft-that-abandoned-transplantation-due-to-poor-graft-conditions-in-the-centers-allocated-as-a-priority/. Accessed July 30, 2021.
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