Cardiac disorders are very common in individuals with chronic kidney disease and are associated with high morbidity and mortality. The purpose of this study was to evaluate the impact of successful kidney transplantation on systolic and diastolic ventricular dysfunction in patients with end-stage renal disease (ESRD).
We prospectively evaluated 200 patients with ESRD, immediately before and one year after kidney transplantation, using tissue Doppler echocardiographic study. The left ventricular ejection fraction, systolic and diastolic function parameters were analyzed.
The mean age was 41.6 years and 40% of patients were diabetic. We observed a reduction in left ventricular diastolic diameter (52.3 to 49.5 mm, p = 0.021) after kidney transplantation. The ejection fraction increased compared to basal assessment (69.7% vs. 45.8%, p <0.01). The prevalence of diastolic dysfunction decreased 47% during the evaluated period. Ameloriation of all of the parameters mentioned above was even better in diabetic patients.
Kidney transplantation is known to lead a considerable improvement in left
ventricular systolic and diastolic function of patients with ESRD, and the results seem even more optimistic for the diabetic patients who have higher mortality.
To cite this abstract in AMA style:Cakir U, Berber I, Gurluler E, Gures N, Alim A, Gurkan A. Cardiac Improvement Is Even Better in Diabetic End-Stage Renal Patients after Kidney Transplantation [abstract]. Am J Transplant. 2013; 13 (suppl 5). https://atcmeetingabstracts.com/abstract/cardiac-improvement-is-even-better-in-diabetic-end-stage-renal-patients-after-kidney-transplantation/. Accessed May 28, 2020.
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