ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Analysis of Antibiotic Resistance and Risk Level of Preservation Fluid Microorganisms in Kidney Transplant Recipients

J. Li1, X. Su1, J. Han2, Y. Huang2, W. Wu1, M. Wei2, S. Yuan2, C. Wu1, J. Li1, L. Liu1, C. Wang1

1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2Sun Yat-sen University, Guangzhou, China

Meeting: 2022 American Transplant Congress

Abstract number: 1001

Keywords: Infection, Kidney transplantation, Preservation solutions

Topic: Clinical Science » Infection Disease » 25 - Kidney Infectious Non-Polyoma & Non-Viral Hepatitis

Session Information

Session Name: Kidney Infectious Non-Polyoma & Non-Viral Hepatitis

Session Type: Poster Abstract

Date: Sunday, June 5, 2022

Session Time: 7:00pm-8:00pm

 Presentation Time: 7:00pm-8:00pm

Location: Hynes Halls C & D

*Purpose: As a solution for preserving kidney during procurement and transportation, preservation fluid (PF) is the main method to detect donor-derived infection. But there are few studies analyzing the risk level of microorganisms in PF. Antibiotic resistance of microorganisms in PF is also rarely described.

*Methods: A retrospective study involving 808 kidney transplant recipients from The First Affiliated Hospital of Sun Yat-sen University between April 2015 to October 2020 was conducted. Exclusion criteria included the absence of preservation fluid and living donor transplants. The microbiological distribution, antibiotic resistance and early postoperative infections including donor-derived infections (DDI) were analyzed. ESKAPE is an acronym comprising the scientific names of six highly virulent and antibiotic resistant bacterial pathogens.

*Results: The total positive rate of PF was 40.7% (329/808) and the main microorganism was coagulase-negative Staphylococci (34.49%). Moreover, higher incidence of bloodstream infection (P=0.006) and perirenal infection (P=0.004) was found in the PF positive group. In the meantime, the antibiotic resistance rate was up to 54.4% (179/329) and the early postoperative infections and DDI were more likely to occur in the antibiotic resistant group. Among the 329 patients, ESKAPE group accounted for 31.6% (104), Candida group accounted for 9.7% (32), ESKAPE and Candida group accounted for 6.1% (20), and other microorganisms accounted for 52.6% (173). Furthermore, we identified 7 patients with DDI (2.1%). We found that DDI (P=0.005), bloodstream infection (P=0.033) and perirenal infection (P=0.000) were more likely to occur in ESKAPE or Candida groups compared to other microorganisms groups. Interestingly, the incidence of DDI in ESKAPE group with extensively drug resistant was up to 13.2%.

*Conclusions: PF positive is significant in the occurrence of early postoperative infections, especially in perirenal infection and bloodstream infection and antibiotic resistance microorganisms need to be concerned. Also, ESKAPE or Candida have a higher risk of DDI transmission, which requires more attention.

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

To cite this abstract in AMA style:

Li J, Su X, Han J, Huang Y, Wu W, Wei M, Yuan S, Wu C, Li J, Liu L, Wang C. Analysis of Antibiotic Resistance and Risk Level of Preservation Fluid Microorganisms in Kidney Transplant Recipients [abstract]. Am J Transplant. 2022; 22 (suppl 3). https://atcmeetingabstracts.com/abstract/analysis-of-antibiotic-resistance-and-risk-level-of-preservation-fluid-microorganisms-in-kidney-transplant-recipients/. Accessed May 30, 2025.

« Back to 2022 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences