*Purpose: The purpose of this report is to describe one OPO’s experience in participating in the Hope Project. This research project is designed to evaluate and determine if it’s safe to transplant HIV+ recipients with organs from HIV-infected deceased donors. LifeGift works closely with John Hopkins University to provide blood specimens as well as HIV + organs to help HIV + and HIV- individuals that are currently on the transplant waitlist. This approach increases the donor supply.

*Methods: This is an observational study using data retrieved from Redcap. Data points are donor referrals received through our call center that had a history of HIV or positive serologic results. As shown in the graph⋯., the screening process proceeded through numerous steps to determine if and which organs and specimens could be available for transplantation.

*Results: Organ donor referrals meeting criteria for inclusion in the research project have increased over the three year period. A total of 154 referrals were received resulting in 107 with a reported history of HIV. From this pool, the OPO has facilitated donation from 37 HIV-positive donors. 20 recoveries were blood only collection, 18 donors had organs recovered (14 kidneys and 4 livers) resulting in 12 organs transplanted (8 kidneys and 4 livers).

*Conclusions: Three years since joining the Hope Study, this OPO has continued to provide enrolled transplant centers with additional opportunities for HIV+ candidates to receive transplanted organs from HIV+ donors. Through participation in the program, the OPO has facilitated an additional 12 organ transplants that without this program, would not have occurred.

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