*Purpose: The Centers for Disease Control and Prevention identified solid organ transplant (SOT) recipients as persons at high risk to develop severe illness secondary to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). We reviewed the clinical characteristics and outcomes of SOT recipients who had SARS-CoV-2 at our center.

*Methods: This was a retrospective review of SOT recipients diagnosed with SARS-CoV-2 between March 1^st 2020 and September 31^st 2020 in the Medical University of South Carolina (MUSC) Health Care system. Subjects were included if they had undergone SOT at any time prior to a positive SARS-CoV-2 PCR. Descriptive statistics were used to analyze demographic and clinical characteristics. Primary outcomes included need for hospitalization, complications, and estimated all-cause mortality.

*Results: 51 SOT recipients were diagnosed with SARS-CoV-2. Five patients were excluded as they initially tested positive and were admitted to another facility. 46 SOT recipients were analyzed, of which, 31 (67%) were hospitalized. Of those hospitalized, 45% were males, 68% were black and 71% were kidney transplant recipients. Median length of stay was three days (range 0.6-108.6). 10 (32%) patients required supplemental oxygen and 6 (19%) received care in the intensive care unit. Complications, including bacterial infections (16%), fungal infections (3%), CMV reactivation (6%), and rejection (3%) were rare. One patient (2%) died during the study time period.

*Conclusions: The majority of SOT recipients with SARS-CoV-2 in our cohort required admission, however they experienced few complications and a low mortality, despite their high-risk status.

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