Viral Enteritis in Intestinal Transplant Recipients
Nebraska Medicine, Omaha, NE
Meeting: 2019 American Transplant Congress
Abstract number: D350
Keywords: Intestinal transplantation
Session Information
Session Name: Poster Session D: Small Bowel: All Topics
Session Type: Poster Session
Date: Tuesday, June 4, 2019
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall C & D
*Purpose: To evaluate viral enteritis episodes in intestinal transplant recipients (ITR)
*Methods: This retrospective review included ITR transplanted between January 2008 and December 2016. Data for the first viral enteritis episode (norovirus, adenovirus, rotavirus, and/or sapovirus) within 1 year post-transplant was collected. Re-transplanted patients were excluded. The primary outcome was incidence of viral enteritis post-transplant. Secondary outcomes included time-to-clinical resolution, hospital length of stay, and treatment. Descriptive statistics were performed.
*Results: Of 139 ITR evaluated, 88 viral enteritis episodes occurred. The incidence of enteritis was: 26% norovirus, 25% adenovirus, 9% each rotavirus, and sapovirus. Pediatric patients had a higher incidence of viral enteritis than adults (Table 1). Median time-to-clinical resolution, hospital length of stay, and treatment administered are presented in Table 2.
*Conclusions: There was a higher incidence of viral enteritis in pediatric ITR compared to adults. The majority of viral enteritis episodes resolved within one week.
| Pediatric Patients (N=99) | Adult Patients (N=40) | |
| Norovirus, n (%) | 34 (34) | 2 (5) |
| Adenovirus, n (%) | 34 (34) | 1 (3) |
| Rotavirus, n (%) | 12 (12) | 1 (3) |
| Pediatric Patients (N=25) | Adult Patients (N=19) | |
| Sapovirus, n (%) | 4 (16) | – |
| Variable | Norovirus | Adenovirus | Rotavirus | Sapovirus |
| Days until clinical resolution, median, range | 4 (1-92) | 5 (1-46) | 6 (2-13) | 4.5 (2-46) |
| Hospital length of stay (days), median, range | 21 (2-287) | 42.5 (1-222) | 38
(7-154)
|
32 (4-84) |
| Change in nutrition status, n (%) | 24 (69) | 17 (49) | 10 (91) | – |
| Anti-motility agent administered, n (%) | 4 (11) | 4 (11) | 1 (9) | – |
| Anti-emetic agent administered, n (%) | 5 (14) | 3 (9) | 3 (27) | 1 (25) |
| Increased IVF administration, n (%) | 16 (46) | 12 (34) | 7 (64) | 1 (25) |
To cite this abstract in AMA style:
Servais A, Vacha M, Florescu DF, Keck M. Viral Enteritis in Intestinal Transplant Recipients [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/viral-enteritis-in-intestinal-transplant-recipients/. Accessed November 22, 2024.« Back to 2019 American Transplant Congress