Five Years after Right Hepatectomy for Living Liver Donation: Donor State of Health
D. P. Hoyer, E. Malamutmann, G. Bagias, A. Oezcelik
General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
Meeting: 2019 American Transplant Congress
Abstract number: B330
Keywords: Liver transplantation, Living-related liver donors
Session Information
Session Name: Poster Session B: Liver: Living Donors and Partial Grafts
Session Type: Poster Session
Date: Sunday, June 2, 2019
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall C & D
*Purpose: Of utmost importance in living liver donation is the avoidance of postoperative complications and reduction of quality of life of the donor.
*Methods: Inclusion criteria for this study were liver donors between 01/2005 and 12/2013 with a completed follow-up of at least 5 years and personal availability. Retrospectively, preoperative, intraoperative and postoperative donor data were investigated. Additionally, all donors received a survey regarding their quality of life. Statistical analysis was performed with Graph Pad Prism (GraphPad Sofware, Inc. Version 8.0.0).
*Results: We included 192 living liver donors (median age 31 years) in this study. Donor characteristics are displayed in table 1. Postoperative complications were observed in 32 (16.6.%) patients, two of these were classified as severe complications (>3b Dindo-Clavien) and subsequently treated by surgical intervention.
Results of the questionnaire demonstrated excellent status of health in 91.7% of donors. General physical performance was excellent or good in 85.5% and 99.5% of donors reported to live daily life as not having been treated surgically before.
None of the donors reported disadvantages in their work life due to the donation. More than two thirds (70.2%) of donors would definitely decide to donate again, this included the two patient with severe complications (table 2). No difference was observed between donors with and without complications.
*Conclusions: Living liver donors have excellent quality of life in the long term. Satisfaction with the surgical interventions is high as well.
Gender (m/f) | 99/93 |
BMI | 24.5 (IQR 22.4-27.0) |
Ratio Remnant to total Liver volume | 35% (IQR 32%-37%) |
Duration of Surgery (minutes) | 260 (IQR 205-315) |
Bilirubin on POD 7 (mg/dl) | 1.0 (IQR 0.7-1.9) |
INR on POD 7 | 1.2 (IQR 1.1-1.3) |
Questions | Answers | ||||
What is your state of health | excellent: 28.9% | good: 62.8% | moderate: 17.3% | bad: 1.0% | very bad: 0% |
How is your general physical condition | excellent: 16.1% | good: 69.4% | moderate: 12.5% | bad: 1.5% | very bad: 0.5% |
Did you have psychological problems after donation | yes, lots: 3.0% | yes, some: 24.6% | no: 72.4% | ||
When did life return to normality | <3months: 47.9% | 3-6months: 27.2% | 6-12months: 18.7% | >12months: 5.7% | Never: 0.5% |
Did you have professional disadvantages due to donation | yes: 0% | no: 100% | |||
Would you decide for donation again today | yes: 70.2% | I don’t know: 24.4% | no: 5.4% |
To cite this abstract in AMA style:
Hoyer DP, Malamutmann E, Bagias G, Oezcelik A. Five Years after Right Hepatectomy for Living Liver Donation: Donor State of Health [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/five-years-after-right-hepatectomy-for-living-liver-donation-donor-state-of-health/. Accessed November 22, 2024.« Back to 2019 American Transplant Congress