Introduction Delayed graft function (DGF), defined as dialysis needed the first week after transplantation are related with poor graft outcomes. There are few information about slow graft function without dialysis needed. We aimed to study the impact of IGF vs SGF and DGF on renal function and graft survival both short and long-term, as well as the risk factors implicated on SGF/DGF development.

Methods Retrospective study from 589 deceased donor kidney transplants (DDKT) in our center between January 2004 and December 2015. We excluded KT from donors < 18 years old and cases of primary non function.

Results 451 KT were included. We reported DGF in 187 (41.5%) recipients , SGF in 186 (41.2%) and 78 with IGF (17.3%). Univariate analysis showed that donor's age and gender, recipient's age, time on dialysis, arterial hypertension, diabetes mellitus, and cold ischemia time , were related to DGF. Independent risk factors to DGF were: cold ischemia time, donor gender (male) , arterial hypertension, time on dialysis and recipient age. Independent risk factors for SGF were higher KDPI score (OR (per point in KDPI) and history of diabetes mellitus.

In unadjusted analysis both DGF and SGF were related with worse graft function nd graft renal function at 1 and 5 years In multivariate analysis neither DGF nor SGF are not related with graft outcomes and SGF was related with best graft survival . DGF and SGF were related with lower estimated glomerular filtration at one year. At 5 years only SGF was related with worse graft function.

Conclusions: Several donor, recipient and transplantation variables are related with DGF and SGF. Classical definition of DGF as dialysis needed do not provide graft prognostic information in our sample, IGF could be a best form to define graft function recovery in terms of prognostic capacity.

CITATION INFORMATION: Arias-Cabrales C., Pérez-Sáez M-.J., Redondo-Pachón D., Crespo M., Mir M., Pascual J. Impact of Immediate Graft Function in Kidney Transplant Outcomes Am J Transplant. 2017;17 (suppl 3).

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