Impact of Aortic Abdominal Calcification among Living Donor Liver Transplant Recipients; a Retrospective Study

Y. Imaoka, M. Ohira, S. Simizu, H. Tahara, K. Ide, Y. Tanaka, H. Ohdan.

Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

Meeting: 2018 American Transplant Congress

Abstract number: C232

Keywords: Liver transplantation, Outcome

Session Information

Session Name: Poster Session C: Liver: Recipient Selection

Session Type: Poster Session

Date: Monday, June 4, 2018

Session Time: 6:00pm-7:00pm

Presentation Time: 6:00pm-7:00pm

Location: Hall 4EF

Abdominal aortic calcification (AAC) is known as a risk factor of coronary artery disease, stroke, hyperphosphatemia, chronic inflammation, diabetes, and decreased an estimated glomerular filtration rate. We analyzed the outcomes of living donor liver transplantation (LDLT) for patients with AAC. Of 141 consecutive patients with LDLT between January 2007 and December 2014, we divided the patients into two groups according to the AAC levels calculated by AZE Virtual Place Lexus64 Anatomia software. The survival time of patients with low AAC was significantly longer than that of patients with high AAC (median survival time 5.08 vs 2.95 years [p = 0.0101]) even after propensity score matching. Multivariate analysis identified the high AAC (hazard ratio 2.167) and old donor (hazard ratio 2.291) as prognostic factors for overall survival.

Multivariate analysis	OR	CI	p-value
Donor age (Y) ≥50	2.2910	1.2158-4.1585	0.0114
AAC (mm³) ≥100	2.1667	1.2087-3.9425	0.0095

There was no effect of high AAC on post-operative complications. However, high AAC leads to worse survival in patients with blood stream infection after LDLT (p = 0.0313). In conclusion, high AAC was an independent unfavorable prognostic factor.

CITATION INFORMATION: Imaoka Y., Ohira M., Simizu S., Tahara H., Ide K., Tanaka Y., Ohdan H. Impact of Aortic Abdominal Calcification among Living Donor Liver Transplant Recipients; a Retrospective Study Am J Transplant. 2017;17 (suppl 3).

To cite this abstract in AMA style:

Imaoka Y, Ohira M, Simizu S, Tahara H, Ide K, Tanaka Y, Ohdan H. Impact of Aortic Abdominal Calcification among Living Donor Liver Transplant Recipients; a Retrospective Study [abstract]. https://atcmeetingabstracts.com/abstract/impact-of-aortic-abdominal-calcification-among-living-donor-liver-transplant-recipients-a-retrospective-study/. Accessed November 24, 2024.

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