Background and Aims: Common Bile Duct Strictures (CBDS) are a significant source of morbidity after liver transplantation (LT) We report our outcomes of endoscopic treatment in CBDS after LT and factors affecting success.

Methods: We collected de-identified data on patients undergoing endoscopic therapy for CBDS with at least 6 months follow up from January 2004 to November 2016. Demographics, etiology of liver disease, transplant/procedure details, complications and survival data were collected. Patency rate was calculated as the number of procedures required to resolve the CBDS. Endoscopic failure was defined by the need for surgical revision despite endotherapy.

Results: 213 procedures were performed with 143 stents placed in 51 patients. The median age was 58y. Median time from transplant to first ERCP for suspected CBDS was 49 days (avg 224 days). 97 plastic stents and 46 SEMS were placed. An average of 3.7 (median 3) stenting procedures were needed for stricture resolution. The success rate of endotherapy was 83%; 8 patients required surgery. Cold ischemia time (CIT) of the donor organ did not appear to affect the ability to endoscopically treat CBDS. Differences in patients successfully treated with endotherapy vs those failing endotherapy are outlined in Table 1.

Conclusion: We report a large single center experience of endotherapy using a combination of SEMS/plastic stents to treat post-transplant CBDS. Endotherapy was successful 83% of the time with a median of 3 procedures per patient. Post-transplant CBDS appear to be effectively treated with endotherapy

CITATION INFORMATION: Woller H, Mantry P, Mejia A, Cheng S, Fasola C. Endoscopic Therapy of Bile Duct Strictures After Liver Transplant. Am J Transplant. 2017;17 (suppl 3).

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