Kidney Donor Profile Index (KDPI) was designed to estimate the graft loss risk in deceased donor transplants. Recently, the Epidemiology Research Group for Organ Transplantation created the living donor kidney profile (LDKPI). This model predicts risk of graft loss after living donor transplant on the same scale as KDPI. Herein, we applied LDKPI to our population to analyze its performance.

Methods: Retrospective analysis of all living donor kidney transplants (2003 to 2015) from two transplant centers in Veracruz, Mexico. LKDPI was calculated in a web-page (www.transplantmodels.com) Donor/Recipient demographics and transplant data included in the model were registered. Pearson correlation between LKDPI percentage and survival was performed. Kaplan-Meier survival (log-rank) and Cox regression analysis was compared between LKPDI quartiles. P < 0.05 was considered significant.

Results: 605 transplants were included. Table 1 displays donor/recipient data for LKDPI calculator Mean LKDPI was – 2.32 ± 13.6 (-39 to 42 range). Pearson coefficient correlation between LKPI and graft survival was -0.82 (95% IC -0.165 to -0.001) (p=0.044). Recipients with the lowest LKDPI had lower risk of one and five year graft loss than other quartiles (p=0.012 log rank) (Figure1) Cox regression analysis was significant for lower LKDPI quartile (-39 to -11) (p=0.027, Exp B= 0.258 95%IC[cedil]0.300-0.929) Conclusion: LKPI confidently applies in cumulative graft loss during first five years of kidney transplant. Longer survival might be influenced by other factors in our population.

CITATION INFORMATION: Martinez-Mier G, Soto-Miranda E, Avila-Pardo S, Budar-Fernandez L, Mendez-Lopez M, Moreno-Ley P, Aguilar-Sandoval E, Coello-Torres G, Diaz-Trueba F. Retroactive Application of a New Risk Index for Living Donor Kidney Transplantation (LKDPI) to Renal Transplants in Veracruz, Mexico. Am J Transplant. 2017;17 (suppl 3).

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