Introduction: Many studies or registries particularly in Japan, but also in Western Europe, have shown that long-term results from ABO-incompatible (ABOi) living-kidney transplantation are as good as those observed for ABO-compatible (ABOc) living-kidney transplantation.

However, it has been reported more posttransplant complications in ABOi patients, such as bleedings or infections.

Methodology: In our single-center retrospective study we assessed all relevant complications occurring within the first 6 months posttransplantation in 44 ABOi and in 44 matched ABOc patients. All patients were comparable at baseline except that ABOi patients had greater immunological risks.

Results: During the 6-month posttransplant period, more ABOi patients presented with postoperative bleeds, thus requiring significantly more blood transfusions. Bleeds were associated with significantly lower values of fibrinogen, platelets, prothrombin time, and hemoglobin levels in the immediate pretransplant period.

Significantly more BK-virus infections occurred in the ABOi group.

Surgical complications, patient- and graft-survival rates, and kidney-function statuses were similar between both groups at 6 months posttransplantation.

Conclusion: We conclude that impairment of hemostatic factors in ABOi patients at pretransplant explained the increased risk of a bleeding episode at posttransplant.

CITATION INFORMATION: Rostaing L, Allal A, Naciri Benami H, Abdulrahman Z, Esposito L, Sallusto F, Doumerc N, Game X, Debiol B, Congy N, Kamar N. Early Posttransplant Complications Following Abo-Incompatible Kidney Transplantation. Am J Transplant. 2016;16 (suppl 3).

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