Outcomes of Solid Organ Transplants Following Simultaneous Solid Organ and Vascularized Composite Allograft Procurements.
1Department of Surgery, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
2Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
3Department of Surgery, Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Meeting: 2016 American Transplant Congress
Abstract number: A86
Keywords: Donors, Graft survival, Outcome, Procurement, unrelated
Session Information
Session Name: Poster Session A: Clinical Vascularized Composite Allotransplantation
Session Type: Poster Session
Date: Saturday, June 11, 2016
Session Time: 5:30pm-7:30pm
Presentation Time: 5:30pm-7:30pm
Location: Halls C&D
Background: Current knowledge of the impact of facial vascularized composite allograft (VCA) procurement on the transplantation outcomes of the concomitantly recovered life-saving organs is limited to isolated case reports and short-term results. Here we report the largest series to date of facial allograft donor surgery experience and long-term outcomes of the concomitantly recovered solid organs and their recipients.
Methods: We performed facial VCA procurements in 7 organ donors between April 2009 and October 2014. We identified the population of subjects who received solid organs from these 7 donors using the Scientific Registry of Transplant Recipients. We retrospectively reviewed operative characteristics, intra-operative parameters, and postoperative outcomes.
Results: Six of seven donor surgeries were performed at outside institutions, all on brain-dead donors. Mean operative duration for facial VCA recovery was 4.9 hours (range 4 – 7 hours). A total of 23 solid organs were recovered and transplanted into 23 recipients
| Location | BWH | OSH | OSH | OSH | OSH | OSH | OSH |
| Length of facial allograft procurement (h) | 7 | 4 | 4 | 4 | 5 | 5.5 | 5 |
| PRBC transfused | 6 | 0 | 0 | 0 | 0 | 0 | 1 |
| Number organs recovered | 1 | 3 | 3 | 2 | 3 | 3 | 8 |
| Organs recovered | Heart | Liver , Kidneys | Liver , Kidneys | Liver , right Kidney | Liver , Kidney | Liver , Kidney | Liver (Split) Kidneys , Heart, Left Lung, Intestine, pancreas |
. Survival rates for kidney and liver recipients were 100% at a median follow-up of 36 months. Graft survival rates for kidneys and livers were 10/11 (91%) and 7/7 (100%), respectively. An intestine recipient was on oral feeds at 6 months. The pancreatic (n=1) and single lung (n=1) recipients were alive and their grafts functioning at 6-months follow-up, respectively. No data has been reported for one heart recipient.
Conclusions: Our protocol for facial VCA procurement does not appear to adversely affect the outcomes of transplant recipients of concomitantly recovered solid organ allografts.
CITATION INFORMATION: Alhefzi M, Aycart M, Sharma G, Krezdorn N, Bueno E, Talbot S, Carty M, Pomahac B, Tullius S. Outcomes of Solid Organ Transplants Following Simultaneous Solid Organ and Vascularized Composite Allograft Procurements. Am J Transplant. 2016;16 (suppl 3).
To cite this abstract in AMA style:
Alhefzi M, Aycart M, Sharma G, Krezdorn N, Bueno E, Talbot S, Carty M, Pomahac B, Tullius S. Outcomes of Solid Organ Transplants Following Simultaneous Solid Organ and Vascularized Composite Allograft Procurements. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/outcomes-of-solid-organ-transplants-following-simultaneous-solid-organ-and-vascularized-composite-allograft-procurements/. Accessed May 21, 2025.« Back to 2016 American Transplant Congress