2015 American Transplant Congress
Vaccination to Prevent the High Herpes Zoster Incidence After Renal Transplantation
Introduction: Herpes zoster (HZ) is the clinical manifestation of varicella zoster virus (VZV) reactivation and occurs more frequently in people with a suppressed immune system.…2015 American Transplant Congress
The Effect of Influenza Vaccination on Hospital Admission in Solid Organ Transplant Recipients
Emory University Hospital, Atlanta, GA.
Purpose: The current study has two objectives. First, compare clinical outcomes between solid organ transplant (SOT) recipients who receive influenza vaccination and those who do…2015 American Transplant Congress
CFZ533: Assessment of Immunomodulatory Activity Following Single Doses of a Novel Anti-CD40 mAb in Healthy Volunteers
Blocking the CD40-CD154 pathway has been shown to effectively prolong renal allograft survival in non-human primates. CFZ533 is a novel, fully human, Fc-silent, anti-CD40 monoclonal…2015 American Transplant Congress
Vaccine-Induced 'Incognito' CD8+ T Cell Memory Can Disrupt Transplantation Tolerance
Transplant recipients harbor immunity to vaccines and pathogens (e.g. CMV, EBV). Pre-existing immunity can have significant antigen-specific ramifications, usually attributed to heterologous immunity, as pathogen-reactive…
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