2020 American Transplant Congress
Targeting CD4+ T Cell Metabolism Prolongs Graft Survival Age-Specifically
*Purpose: If and how aging affects T-cell metabolism and alloimmune response is unclear. Here, we show that T-cell metabolism changes drastically in aging. Most notably,…2020 American Transplant Congress
Serum αKlotho after Living Kidney Donation: A Systematic Review and Meta-Analysis
*Purpose: αKlotho (klotho) is a known anti-aging protein that exerts diverse physiological effects. Defect in klotho gene expression in mice can result in a syndrome…2020 American Transplant Congress
Older Livers Should Not Be Utilized in Pediatric Liver Transplantation
*Purpose: Organ scarcity in liver transplantation has required expansion of the acceptable criteria used for donor selection. The utilization of older donors (>60 years) has…2020 American Transplant Congress
Evaluation of Infectious and Malignant Complications in Elderly Renal Transplant Recipients Receiving Alemtuzumab Compared to Basiliximab
*Purpose: The choice of induction immunosuppression can affect several outcomes after kidney transplant (KTx), especially for elderly recipients. For this population, there is limited data…2020 American Transplant Congress
Patient and Kidney Allograft Outcomes in Septuagenarians – A Single Center Experience
Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, PA
*Purpose: Based on Scientific Registry of Transplant Recipients reporting, the proportion of patients 65 years or older on the kidney transplant (KT) waiting list has…2020 American Transplant Congress
Pancreas Transplant in Patients Older Than 50: An Analysis of Outcomes and Immunosuppression
*Purpose: Pancreas transplant (PT) is the ideal therapy for many patients with diabetes and kidney failure. There are limited published data addressing the impact of…2020 American Transplant Congress
A Multi-Center Pilot and Feasibility Randomized Clinical Trial of a Home-Based Exercise Program for Patients with Cirrhosis: The Strength Training Intervention
*Purpose: Patients with cirrhosis experience progressive physical frailty and functional decline that may ultimately lead to an increased risk of death. We developed the Strength…2020 American Transplant Congress
Outcomes after Declining Offers from Older Donor Kidneys for Kidney Transplant Candidates
Johns Hopkins University, Baltimore, MD
*Purpose: Older donor kidneys (ODKs) are often declined as they are associated with higher post-transplant mortality and graft loss, yet those who decline may wait…2020 American Transplant Congress
Effect of Increased Recipient Age on Solid-Organ Pancreas Transplantation Outcomes: A Systematic Review
Nephrology, Monash Medical Centre, Clayton, Australia
*Purpose: Increased recipient age has been associated with poorer solid organ pancreas transplant (SOPTx) outcomes. We hypothesized that recipient age cut-offs in Australia and New…2020 American Transplant Congress
Extracellular Vesicles Mediate Endothelial to Mesenchymal Transition and Tubular Senescence in Renal Antibody- Mediated Rejection by Inducing Complement Activation
Emergency and Organ Transplantation, University of Bari, Bari, Italy
*Purpose: EVs (Extracellular vesicles), circulating microparticles able to mediate cell-to cell communication, are emerging as pivotal in different kidney diseases. Renal Antibody-Mediated Rejection (AMR) is…
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