2020 American Transplant Congress » Poster Session A: Biomarker Discovery and Immune Modulation

3:30pm-4:00pm

Antibiotic Pretreatment Alleviates Liver Transplant Damage by Modulating the Composition of Commensal Microbiota

K. J. Dery, S. Kageyama, H. Hirao, K. Kadono, H. Kojima, R. W. Busuttil, J. W. Kupiec-Weglinski

3:30pm-4:00pm

Cell-Free DNA (cfDNA) is Released by Necroptosis and Promotes Kidney Ischemia Reperfusion Injury

A. C. Dionne

3:30pm-4:00pm

Characterization of Laminin Alpha 4 Conditional Knockout Mice: Model for Immune Stimulation

M. W. Shirkey, L. Li, W. Piao, Y. Xiong, V. Saxena, T. Zhang, C. Paluskievicz, J. Bromberg

3:30pm-4:00pm

Dominant Negative Polymorphisms in TNFRSF13B are Associated with Poor Transplant Outcome

M. G. de Mattos-Barbosa¹, E. T. Luning Prak², E. Farkash³, J. L. Platt⁴, M. Cascalho⁴

3:30pm-4:00pm

Immunomodulation During Normothermic Ex Vivo Machine Perfusion of the Rat Liver

K. Carlson¹, F. Najmabadi¹, J. Pavan-Guimaraes¹, W. J. Burlingham¹, C. M. Capitini², D. P. Al-Adra¹

3:30pm-4:00pm

Integrated Multicohort Analysis of Transcriptome Profiles Identifies Blood Gene Signature to Distinguish Rejection from Infection in Patients with Solid Organ Transplants

L. C. Murphy, A. Rao, M. Donato, P. Khatri

3:30pm-4:00pm

Is it Time for Immune Screening for Belatacept-Treated Stable Kidney Transplant Patients for Adjust the Immunosuppression?

M. C. Rial¹, F. Caro², N. Ambrosi², D. Guerrieri², A. Calleri¹, E. Chuluyan¹, D. Casadei¹

3:30pm-4:00pm

Metformin Improves Biomarkers of Calcineurin Inhibitor Related Nephrotoxicity

M. R. Fernando, K. Taylor, S. Herath, A. Au, J. Erlich, Z. Endre

3:30pm-4:00pm

Microarray and RNA-Seq Analysis of Rejection in Formalin-Fixed Paraffin-Embedded (FFPE) Biopsies: Comparing FFPE to Conventionally Stabilized (RNAlater Solution) Biopsies

P. Halloran¹, K. Famulski¹, J. Reeve¹, J. Huang², N. Alexandrov²

3:30pm-4:00pm

Novel Flow-Based Assay to Detect Allospecific T Cells in Transplantation Study

N. Tanimine¹, B. E. Burrel², J. Pardo², C. Rickert³, K. M. Lee³, K. Deng³, N. Feeney³, C. Leguern³, J. F. Markmann³

3:30pm-4:00pm

Novel micro-RNA and Microbiome Signature Profiles as Biomarkers for Predicting the Risk of Autoimmune Type 1 Diabetes Development

P. Chhabra¹, G. Ricardo¹, A. Spano², V. Mas¹, M. Timko², K. Brayman¹

3:30pm-4:00pm

Prognostic Impact of Peritumoral Neutrophil Infiltration on Hepatocellular Carcinoma Recurrence Following Liver Transplantation

M. Najjar¹, K. Halazun², M. Mondal¹, A. Srivastava¹, M. Moore¹, E. Rizk¹, R. Gartrell¹, H. Remotti¹, L. Fazlollahi¹, E. Verna¹, A. Griesemer¹, A. Mathur¹, B. Samstein², J. Emond¹, Y. Saenger¹

3:30pm-4:00pm

Proteomic Profiling of Circulating Extracellular Vesicles Isolated from Human Lung Transplant Recipients

S. Bansal¹, M. McGilvrey², K. Garcia-Mansfield², R. Sharma², R. Bremner¹, M. Smith¹, R. Hachem³, P. Pirrotte², T. Mohanakumar¹

3:30pm-4:00pm

Serum CXCL13 Levels Indicate Humoral Alloreactivity and Donor Specific Antibody Formation

E. S. Crichton, S. Zeng, I. Badell

3:30pm-4:00pm

Small RNA Extracellular Vesicles Isolated from Liver Perfusate Provides Assessment of Organ Quality and Post Transplantation Graft Function

A. Bajwa, C. Kuscu, C. Kuscu, A. R. Wolen, J. D. Eason, D. Maluf, V. Mas

3:30pm-4:00pm

T-cell Receptor Deep Sequencing to Distinguish Autoimmune Recurrence from Allograft Rejection in Liver Transplant Patients with Autoimmune Liver Disease

K. J. Yang¹, M. Martinez², B. Shonts¹, C. A. Parks¹, A. Z. Obradovic¹, T. M. Savage¹, E. Spyrou¹, S. Lau¹, M. I. Colquhoun¹, K. Rodgers¹, E. Verna³, S. M. Coley⁴, S. Yang¹, Y. Shen⁵, M. Sykes¹

3:30pm-4:00pm

Thalidomide and Dexamethasone Combinatorial Treatment Induces Tolerogenic Signals by Systemic Immunomodulation of T Cells and Dendritic Cells

B. Kim¹, E. Kim², J. Kim², H. Choi³, H. Lee², J. Lee⁴, M. Kim⁴, Y. Kim⁴, K. Huh⁴

3:30pm-4:00pm

The Transcriptomic Analysis Revealed a Clear Deregulation of the C1QB Gene in Peripheral Blood Mononuclear Cells of Renal Transplant Patients with Chronic Antibody Mediated Rejection

G. Zaza¹, S. Granata¹, G. Santoro¹, C. Caletti¹, P. Pontrelli², F. Rascio³, M. Rossi¹, S. Andrighetto¹, G. Grandaliano⁴

3:30pm-4:00pm

Transplant Relevant MDSC Genetics: Differential Gene Expression Profiles of Immunosuppressive Myeloid-Derived Suppressor Cells Induced by Granulocyte-Colony Stimulating Factor

Y. S. Lee, J. S. Bromberg, J. R. Scalea

3:30pm-4:00pm

Unique Genomic & Proteomic Profile of Liver Mesenchymal Stromal Cells is Associated with Their Superior Immunomodulatory Properties

F. Yigitbilek, W. D. Park, N. Abrol, M. D. Stegall, T. Taner