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2022 American Transplant Congress

TOPIC: Basic Science » Basic Science » 13 - Xenotransplantation

  • Life Supporting Orthotopic Cardiac Xenotransplantation Using Multiple Human Gene Expressing Pigs in Non Human Primates

    A. K. Singh1, C. Goerlich1, T. Zhang1, I. Tatarov1, P. Odonkor1, E. Strauss1, B. Williams1, B. Lewis1, A. Hershfeld1, F. Sentz1, D. Ayares2, D. Kaczorowski1, B. Griffith1, M. Mohiuddin1

  • Long-Term (>1 Year) Rejection Free Graft Survival of Kidney Xenografts with Triple Xenoantigen Knockout and Multiple Human Transgenes in Cynomolgus Monkeys

    T. Hirose1, G. Lassiter1, D. Ma1, A. D'Attilio1, I. Rosales1, D. Cloonan1, R. Matheson1, R. Colvin1, W. Qin2, Y. Kan2, J. Layer2, R. Anand2, V. Paragas2, L. Queroz2, X. Tan2, I. Kohnle2, K. Stiede2, K. Hall2, M. Youd2, M. Curtis2, J. Markmann1, T. Kawai1

  • Multiomic Analyses Of Two Pig Kidney To Human Xenotransplants

    B. Keating1, B. Piening2, M. Mangiola3, J. Stern4, W. Zhang5, A. Griesemer6, B. Lonze7, M. Snyder8, J. Boeke5, R. Montgomery7

  • Overexpression of Human Ectonucleoside Triphosphate Diphosphohydrolase 1 (entpd1; Hcd39) Did Not Afford Significant Protection on Porcine Endothelial Cells

    R. Matheson1, B. Gonzalez Nolasco1, K. Deng1, R. Garofalo1, N. Serifis1, T. M. Coe1, C. Rhatigan1, D. Gil1, D. Cloonan1, K. Lee1, K. Hall2, M. Youd2, J. F. Markmann1, S. C. Robson3

  • Post-Xenotransplant Antibody Specificities Against Swine, Monkey and Human Leukocyte Antigens in Highly Sensitized Nonhuman Primate Model

    I. DeLaura, I. Anwar, M. Manook, D. Olaso, J. Yoon, R. Baldi, A. Jackson, S. Knechtle, J. Kwun

  • Pre-Transplantation Liver Immunoadsorption Reduces Liver-Specific Antibody and Complement Deposition without Prolonging Survival in Porcine to Baboon Liver Xenotransplantation

    D. J. Cloonan1, T. Coe1, N. Serifis1, R. Matheson1, S. Maggipinto1, D. Firl1, R. Anand2, J. Layer2, L. Queiroz2, K. Stiede2, K. Hall2, M. Youd2, W. Qin2, M. Curtis2, S. Kimura1, I. Rosales1, J. Markmann1

  • Preclinical Evaluation of Functional Survival of Stem Cell Derived Islets Microencapsulated in Alginate with CXCL12 in Non-Human Primates without Immunosuppression

    M. C. Poznansky

  • Presence of Infiltrating Regulatory T Cells in the Cardiac Xenografts and Their Potential Role in Graft Survival

    A. K. Singh1, C. E. Goerlich1, G. Braileanu1, A. Hershfeld1, T. Zhang1, I. Tatarov1, B. Lewis1, F. Sentz1, D. Ayares2, B. Griffith1, M. M. Mohiuddin1

  • Prolonged Xeno-Kidney Graft Survival in Highly Allo-Sensitized Nonhuman Primate Using Triple-Knockout Donor Pigs with 7 Human Transgenes

    M. Manook1, D. Olaso1, I. Anwar1, J. Yoon1, M. Song1, A. B. Farris2, K. Stiede3, K. Hall3, M. Youd3, S. Knechtle1, J. Kwun1

  • Significant Reduction of Troponin I Elaboration After Ischemia Minimization in the First Hour of Ex Vivo Xeno Heart Perfusion

    F. Pollok1, M. R. Connolly1, A. Calhoun1, Z. Habibabady1, S. Miura1, M. Ma1, S. Pratts1, L. Burdorf1, Y. Kan2, J. V. Layer2, J. V. Layer2, E. Tan2, R. Anand2, M. Li2, K. C. Hall2, M. E. Youd2, K. Stiede2, W. Qin2, M. Curtis2, A. Azimzadeh1, R. N. Pierson1

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