2021 American Transplant Congress

TOPIC: Basic Science » B-cell / Antibody /Autoimmunity

In Vitro Generated Regulatory B Cells Induce Cd4⁺Cd25⁺Foxp3⁺Tregs from Cd4⁺Cd25^–T Cells via TGF-β
G. Huai¹, K. Lee², K. Deng², Q. Fu¹, C. G. Rickert², S. Deng¹, C. LeGuern², J. F. Markmann²
Lung Transplant Recipients Developing Early DSAs are Characterized by a Shift Towards Memory B Cells Directly After Transplantation
S. Christoph¹, A. Hitz¹, R. Bellmàs Sanz¹, J. Kühne¹, B. Wiegmann², F. Ius², J. Salman², E. Chichelnitskiy¹, T. Siemeni², W. Sommer³, A. Haverich², G. Warnecke³, C. Falk¹
Marginal Zone B Cells Support Donor-Specific Alloantibody Responses to Heart Allografts
V. Gorbacheva, R. Fan, W. Baldwin, R. Fairchild, A. Valujskikh
Measuring the Impact of Targeting FcRn-Mediated IgG Recycling on Donor-Specific Alloantibodies in a Sensitized NHP Model
M. Manook¹, W. Flores², R. Schmitz¹, Z. Fitch¹, J. Yoon¹, Y. Bae¹, B. I. Shaw¹, M. Harnois³, S. Permar³, A. Kirk¹, D. Magnani², J. Kwun¹, S. Knechtle¹
Natural Sensitization by Pregnancy, Testing Desensitization Strategies in Female NHPs Across Repeat Mismatches
M. Manook, J. Yoon, Z. Fitch, R. Schmitz, A. M. Jackson, J. Kwun, S. Knechtle
Properties of Regulatory B Cells Suppressing B Cells
Q. Fu¹, K. Lee², K. Deng², G. Huai², C. Rickert², H. Yang¹, C. LeGuern², S. Deng¹, J. F. Markmann²
Quantifying Hidden Sensitization: HLA-reactive Memory B Cells in the Spleens of Sensitized Women
J. T. Killian¹, J. A. Houp¹, A. Nellore², R. G. King³, P. M. Porrett¹, F. E. Lund³
Single Cell RNA Sequencing of Tim1- B Cells and Tim1+ Regulatory B Cells
Q. Fu¹, K. Lee², K. Deng², D. Agarwal³, P. v. Galen⁴, C. G. Rickert², G. Huai², H. Yang¹, C. LeGuern², S. Deng¹, J. F. Markmann²
Suppression of T Cell Proliferation by Activated Nonhuman Primate B Cells
K. Lee, K. Deng, G. Huai, F. Qiang, C. Rickert, J. Lei, C. Leguern, J. Markmann
Targeting Il-21 Receptor Shifts Tfh/tfr Balance and Ameliorateschronic Antibody Mediated Rejection
Y. Nian, Z. Xiong, J. Zhao, Y. Fu