2022 American Transplant Congress

TOPIC: Basic Science

Leveraging Car T Cells To Achieve Desensitization And Enable Transplantation
V. BHOJ
Leveraging Single-Cell Signatures in Kidney Transplant Biopsies Uncovers Immunological Heterogeneity Within Rejection Phenotypes
J. Callemeyn¹, B. Lamarthée¹, P. Koshy², T. Debyser³, E. Van Loon¹, A. Franken⁴, T. Van Brussel⁴, I. Arijs⁴, D. Lambrechts⁴, M. Rabant⁵, A. Senev¹, T. Vaulet⁶, C. Tinel¹, M. Naesens¹
LGALS1 is Expressed in Glomerular Endothelial Cells and Induced Upon Stimulation with Anti-HLA Antibody
A. Boshart¹, S. Farkona¹, S. Clotet-Freixas¹, C. McEvoy¹, J. Murphy¹, S. Crome², A. Konvalinka³
Life Supporting Orthotopic Cardiac Xenotransplantation Using Multiple Human Gene Expressing Pigs in Non Human Primates
A. K. Singh¹, C. Goerlich¹, T. Zhang¹, I. Tatarov¹, P. Odonkor¹, E. Strauss¹, B. Williams¹, B. Lewis¹, A. Hershfeld¹, F. Sentz¹, D. Ayares², D. Kaczorowski¹, B. Griffith¹, M. Mohiuddin¹
Lipid Metabolism Profile of Human Kidneys During Ex Vivo Normothermic Perfusion
J. Yu, I. Palma, S. Adams, J. Sageshima, P. Than, R. Perez
Local Cognate Antigen in Kidney Allografts Promotes Tissue Resident Memory T Cell Maintenance
R. Tieu¹, Q. Zeng¹, D. Zhao¹, P. Manandhar², A. Williams¹, K. Abou-Daya¹, L. Kane², W. Shlomchik¹, M. Oberbarnscheidt¹, F. Lakkis¹
Local Mesenchymal Stem Cell Therapy for the Ex Vivo Preservation of a Porcine Vascularized Composite Allograft with 24-hour Normothermic Machine Perfusion
A. Bernal¹, J. Hinshaw¹, J. Pena¹, C. Hinshaw¹, D. Wood¹, K. Zimmern², N. McMahon², J. Ling², W. Zhang¹, E. Weitzel¹
Long Term Longitudinal TTV Measurements in Lung Transplant Recipients
E. Gore¹, C. Rondaan¹, E. A. Verschuuren², L. Gard¹, H. G. Niesters¹, C. van Leer-Buter¹
Long-Term (>1 Year) Rejection Free Graft Survival of Kidney Xenografts with Triple Xenoantigen Knockout and Multiple Human Transgenes in Cynomolgus Monkeys
T. Hirose¹, G. Lassiter¹, D. Ma¹, A. D'Attilio¹, I. Rosales¹, D. Cloonan¹, R. Matheson¹, R. Colvin¹, W. Qin², Y. Kan², J. Layer², R. Anand², V. Paragas², L. Queroz², X. Tan², I. Kohnle², K. Stiede², K. Hall², M. Youd², M. Curtis², J. Markmann¹, T. Kawai¹
Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft
E. S. Szuter¹, T. Yokose¹, M. T. Guinn¹, J. Ge², I. Rosales³, B. Kwon⁴, P. S. Russell¹, A. Cuenca², D. Kreisel⁵, P. Sage⁶, J. C. Madsen¹, R. B. Colvin³, A. Alessandrini¹