ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Warm ischemia"

  • 2021 American Transplant Congress

    Donation After Cardiac Death (DCD) Agonal Phase Physiology is Associated with Post-transplant Kidney Graft Outcomes

    A. Kayastha1, K. C. Eddinger2, E. M. Sonnenberg2, N. Mahmud2, D. E. Schaubel1, P. L. Abt2

    1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Hospital of the University of Pennsylvania, Philadelphia, PA

    *Purpose: Kidneys procured from DCD donors play a key role in addressing the kidney shortage in the United States, and donor hemodynamics during obligatory warm…
  • 2021 American Transplant Congress

    Hypoperfusion Warm Ischaemia Time in Renal Transplants from Donors After Circulatory Death

    I. D. Kostakis1, T. Kassimatis1, C. Flach2, N. Karydis1, N. Kessaris1, I. Loukopoulos1

    1Department of Transplantation, Guy’s Hospital, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, 2School of Population Health and Environmental Studies, King’s College London, London, United Kingdom

    *Purpose: Donor hypoperfusion before asystole in renal transplants from donors after circulatory death (DCD) has been considered responsible for worse outcomes than those from donors…
  • 2020 American Transplant Congress

    The Learning Curve for Pure Laparoscopic Robotic Kidney Transplantation: An Analysis of Outcomes of the First 80 Consecutive Cases at a High-Volume Transplant Center

    F. Tinney Jr.1, J. Stracke2, T. Ivanics1, A. Elsabbagh1, J. Denny1, D. Kim1, L. Malinzak1, A. Yoshida1

    1Transplant Institute, Henry ford Hospital, Detroit, MI, 2Transplant Surgery, Metro Health Hospital, Wyoming, MI

    *Purpose: Robotic surgery is increasingly used in complex operations, including living-donor kidney transplantation. At this time, knowledge of the number of cases required to attain…
  • 2020 American Transplant Congress

    Creation of a Low-Cost Kidney Transplant Surgery Simulator and Survey of its Utility for Education

    V. Melkonian, T. Huy, C. Varma, M. Nazzal, H. Randall, M. Nguyen

    Department of Surgery, Saint Louis University, Saint Louis, MO

    *Purpose: Surgical skills education in transplant surgery is challenging as center-specific outcomes are scrutinized and trainees’ exposure to the sub-specialty is decreasing. Simulation could overcome…
  • 2020 American Transplant Congress

    Type 1 Innate Lymphoid Cells Are Critical Pro-Inflammatory Effector Cells in a Fatty Liver Mouse Model of Ischemia-Reperfusion Injury

    J. Kang, K. Loh, J. Green, M. Sadat, M. Stovroff, A. Duttargi, B. Kallakury, K. Khan, T. Fishbein, A. Kroemer

    MedStar Georgetown Transplant Institute, Washington, DC

    *Purpose: Innate lymphoid cells (ILCs), the most recently described family of lymphoid cells, play fundamental roles in tissue homeostasis and immune regulation through the activation…
  • 2020 American Transplant Congress

    The Impact of Transportation Innovation for Human Organs: Surgical Perspectives and Implications

    T. Talaie, S. Niederhaus, E. Villalonga, J. Bromberg, J. Scalea

    Transplant Surgery, Unviersity of Maryland Medical Center, Baltimore, MD

    *Purpose: Recent changes in allocation and the ongoing organ donor shortage have led to increased regional and national sharing, putting intense pressure on the organ…
  • 2020 American Transplant Congress

    DCD vs DBD Liver Transplantation: Equivalent Charges and Similar Survival- An Effective Expansion of the Donor Pool

    N. Singh, K. Helfrich, M. Alebrahim, C. Akateh, K. Mumtaz, A. Logan, A. Schenk, S. Black, E. Elkhammas, K. Washburn, A. El-Hinnawi

    Ohio State University, Columbus, OH

    *Purpose: The shortage of allografts available for liver transplantation (LT) has prompted the need for expansion of donor pool to include donation after circulatory death…
  • 2020 American Transplant Congress

    Activation of YAP Attenuates Hepatic Damage and Fibrosis in Liver Ischemia-Reperfusion Injury: From Bench to Bedside

    Y. Liu1, T. Lu2, C. Zhang1, Z. Xue1, R. Busuttil1, J. Kupiec-Weglinski1, H. Ji1

    1Dumont-UCLA Transplant Center, Los Angeles, CA, 2Shanghai Jiaotong University, Shanghai, China

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) is a major complication of hemorrhagic shock, liver resection and transplantation. YAP, the effector of Hippo pathway, is essential in…
  • 2020 American Transplant Congress

    Genome-Wide Transcriptome Analysis of Extreme Marginal Renal Grafts Indicates Earlier Repair and Less Damage Following Normothermic Ex-Vivo Kidney Perfusion Preservation

    P. Urbanellis1, L. Mazilescu1, C. McEvoy1, S. Ganesh1, R. John1, I. Mucsi1, A. Ghanekar1, D. Bagli2, A. Konvalinka1, L. Robinson1, M. Selzner1

    1University Health Network, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada

    *Purpose: Normothermic ex-vivo kidney perfusion (NEVKP) was shown to prevent delayed graft function of kidneys subjected to prolonged warm ischemia (WI) compared to static cold…
  • 2020 American Transplant Congress

    Potential to Regenerate Damaged Allografts

    L. Brasile1, B. Stubentisky2

    1Research and Development, Breonics Inc., Watervliet, NY, 2Plastic, Reconstructive & Aesthetic Surgery, St. Antonius Hospital, Utrecht, Netherlands

    *Purpose: The chronic shortage of allografts has generated intense interest in the field of regenerative medicine. Given the limited regeneration that can be accomplished in…
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