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Articles tagged "Vascular disease"

  • 2018 American Transplant Congress

    Early Life Stress Exposure and Cardio-Renal Outcomes in Pediatric Kidney Transplantation

    M. Seifert, P. Perry, R. Romp, R. Mannon, J. Pollock.

    UAB School of Medicine, Birmingham.

    Purpose: Early life stress (ELS) has emerged as an important cardiovascular risk factor in adulthood, and can be characterized by exposure to adverse childhood experiences…
  • 2018 American Transplant Congress

    Cardiovascular Risk and Subclinical Vascular Damage in Patients after Pediatric Liver Transplantation

    H. Wilke,1 N. Memaran,1 I. Goldschmidt,1 B. Borchert-Mörlins,1 A. von Wick,1 E. Bauer,1 R. Blöte,1 B. Schmidt,2 A. Melk.1

    1Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany; 2Nephrology, Hannover Medical School, Hannover, Germany.

    Cardiovascular (CV) disease causes a high level of morbidity and mortality in adults undergoing solid organ transplantation. Pediatric liver transplant (Li-Tx) recipients were reported to…
  • 2018 American Transplant Congress

    Kidney Allograft Vascular Disease Post-Transplant (KTX): Risk Factors and Implications

    M. El Ters,1 L. Cornell,2 J. Grande,2 F. Cosio.1

    1Medicine, Mayo Clinic, Rochester, MN; 2Pathology, Mayo Clinic, Rochester, MN.

    Background: Over time grafts develop arteriosclerosis (ART)and arteriolar hyalinosis (AH). Previous studies associated AH with calcineurin inhibitors (CNI), diabetes (DM), kidney age and hypertension. Other…
  • 2018 American Transplant Congress

    Vascular Allografts in Renal Transplantation

    D. Reino, G. Schnickel, E. Ale, S. Ebaid, N. Agrawal, S. Rhazouani, S. Gebreselassie, A. Tzakis.

    Solid Organ Transplantation, Cleveland Clinic Florida, Weston, FL.

    Vascular allografts are used routinely in pancreas, intestine and occasionally in liver transplantation. We propose that selective use of vascular allografts may increase utilization of…
  • 2018 American Transplant Congress

    Apoptotic Exosome-Like Vesicles Induce Endothelial Cell Plasticity

    F. Migneault,1,2,4 M. Dieudé,1,2,4 J. Turgeon,1,4 D. Beillevaire,1,2,4 M-.P. Hardy,2,3,4 C. Perreault,2,3,4 M-.J. Hébert.1,2,4

    1CRCHUM, Montreal, QC, Canada; 2Université de Montréal, Montreal, QC, Canada; 3IRIC, Montreal, QC, Canada; 4CNTRP, Montreal, QC, Canada.

    Acute vascular rejection of renal allografts is associated with increased endothelial apoptosis which contributes to the development of transplant vasculopathy. We previously showed that apoptotic…
  • 2018 American Transplant Congress

    Prevalence and Persistence of Cardiovascular Risk Factors and Subclinical Vascular Damage in Patients after Pediatric Lung Transplantation

    M. Onnen,1 N. Memaran,1 B. Borchert,1 R. Blöte,1 R. Sugianto,1 C. Müller,2 A. Melk.1

    1Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany; 2Pediatric Pulmonology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.

    In adults undergoing solid organ transplantation, cardiovascular (CV) disease causes a high level of morbidity and mortality. Children after lung transplantation (Lu-Tx) are prone to…
  • 2018 American Transplant Congress

    Kidney Transplantation and Progression of Peripheral Arterial Disease in the Ipsilateral Lower Extremity

    A. Rasmussen,1 R. Moore,1 T. Schuler,1 G. Todd,1 K. Wen.2

    1Division of Urology, Department of Surgery, University of Alberta, Edmonton, AB, Canada; 2Division of Nephrology and Transplant Immunology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.

    Objectives:We aimed to investigate whether receiving a kidney transplant allograft graft increases the risk of ipsilateral lower limb amputation in patients with pre-existing peripheral arterial…
  • 2018 American Transplant Congress

    Upper Limb Early Cannulation Arteriovenous Grafts (ecAVG) for Complex Vascular Access – A Healthy Alternative to Central Venous Catheters (CVC)

    M. Khurram,1 I. Mosca,2 F. Calder.3

    1Department of Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; 2Department of Transplantation, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom; 3Department of Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

    IntroductionPatients with few transplant options and failing dialysis access are challenging to manage. Transitioning away from a CVC to fistula / graft is often difficult.…
  • 2018 American Transplant Congress

    The Impact of Aorto-Iliac Calcifications on Patient and Graft Survival in Renal Transplant Recipients Using the TASC II Classification

    A. Rijkse,1 M. van der Zijden,2 J. Roodnat,2 S. Ten Raa,3 D. Bijdevaate,4 K. Muller,1 J. IJzermans,1 H. Kimenai,1 R. Minnee.1

    1Department of Transplantation Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; 2Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; 3Department of Vascular Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; 4Department of Radiology, Erasmus University Medical Center, Rotterdam, Netherlands.

    Introduction: Kidney transplantation (KTx) is the therapy of choice in patients with end-stage renal disease. Aorto-iliac calcifications (AIC) are a relative contra-indication for KTx, even…
  • 2018 American Transplant Congress

    A High Abdominal Aortic Calcification Score by Dual X-Ray Absorptiometry (DXA) is Associated with Cardiovascular Events after Kidney Transplantation

    S. Benjamens,1,2 R. A. Pol,1 A. W. Glaudemans,2 I. Wieringa,3 S. P. Berger,3 S. J. Bakker,3 R. H. Slart.2

    1Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Medical Imaging Center, UMCG, Groningen, Netherlands; 3Nephrology, UMCG, Groningen, Netherlands.

    Introduction: It is unknown whether aortic calcification is associated with increased risk for cardiovascular events in renal transplant recipients. Therefore, this study focused on the…
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