Articles tagged "Vascular disease"

2020 American Transplant Congress
The Role of mTOR Inhibitors on Cardiovascular Aging in Renal Transplanted Patients with Chronic Graft Dysfunction
G. Castellano¹, B. Infante¹, P. Pontrelli¹, R. Franzin¹, F. Rascio¹, C. Prisciandaro², L. Gesualdo¹, N. Coviello³, G. Grandaliano³, G. Stallone³
¹Emergency and Organ Transplantation, University of Bari, Bari, Italy, ²University of Foggia, Foggia, Italy, ³Emergency and Organ Transplantation, University of Foggia, Foggia, Italy
*Purpose: Chronic Kidney Disease (CKD) is strongly associated with increased circulatory complications that can lead to accelerated cardiovascular aging. During CKD, persistent oxidative stress triggered…
2020 American Transplant Congress
Unified Management of Inferior Vena Cava Web and Right Hepatic Vein in Living Donor Liver Transplantation for Membranous Obstruction of Vena Cava (Budd Chiari Syndrome)
Y. Nah, S. Park, E. Lee, S. Park
Department of Surgery, Ulsan University Hospital, Ulsan, Korea, Republic of
*Purpose: In Eastern countries Budd Chiari syndrome (BCS) is most often caused by the membranous obstruction of the vena cava (MOVC). During living donor liver…
2020 American Transplant Congress
Predominant Role of Microvascular Injury and Rarefaction Function as Drivers of Progressive Renal Damage and Fibrosis Post Mild and Severe Acute Ischemia-Reperfusion Injury
S. Lan¹, B. Yang¹, J. Sabo-Vatasescu², M. Bourgault², A. Karakeussian-Rimbaud³, J. Turgeon³, S. Qi¹, N. Patey⁴, M. Dieudé⁵, M. Hébert¹
¹Medicine Faculty, CRCHUM, CDTRP, University of Montreal, Montreal, QC, Canada, ²CRCHUM, Montreal, QC, Canada, ³CRCHUM, CDTRP, Montreal, QC, Canada, ⁴Medicine Faculty, CRCHUM, Saint Justine Hospital, University of Montreal, Montreal, QC, Canada, ⁵CRCHUM, CDTRP, University of Montreal, Montreal, QC, Canada
*Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor for chronic renal failure. Here, we characterize the different cell deaths in tubular and microvascular compartments…
2020 American Transplant Congress
Age-Enhanced Transplant Vasculopathy Associates with Impaired Vascular Mitophagy
M. Blin¹, D. Tyrrell¹, S. Wood¹, D. Farris¹, S. G. Tullius², D. R. Goldstein¹
¹Micro and Immunology/Internal Medicine, University of Michigan, Ann Arbor, MI, ²Transplant Surgery, Brigham and Women's Hospital, Boston, MA
*Purpose: Donor aging leads to increased chronic allograft vasculopathy (CAV) for unclear reasons. Here, we investigated whether impaired alterations in mitophagy, a mechanism to remove…
2020 American Transplant Congress
Glomerular Filtration Rate Based on Cystatin C Provides the Best Prediction of Cardiovascular Events and Mortality Compared to Measured GFR and Creatinine Based GFR in Kidney Transplant Recipients
L. Galapia¹, J. Lieske², A. Rule², H. Amer², N. Zhang¹, D. Butterfield¹, M. Keddis¹
¹Mayo Clinic, Scottsdale, AZ, ²Mayo Clinic, Rochester, MN
*Purpose: GFR estimated by cystatin C (CysC) is a better predictor of cardiovascular (CV) events and mortality compared to eGFR by creatinine (Cr) in native…
2020 American Transplant Congress
Retinal Vein Occlusion Incidence in Kidney Transplant Recipients in South Korea: A Long-Term Population-Based Study
J. Lee¹, S. Park¹, J. Kim¹, M. Yu², S. Baek³, K. Han⁴, D. Kim¹, K. Joo¹, Y. Kim¹, H. Lee¹, Y. Kim¹
¹Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ²Department of Internal Medicine, Hanyang University Medical Center, Seoul, Korea, Republic of, ³Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea, Republic of, ⁴Medical Statistics, College of Medicine, Catholic University of Korea, Seoul, Korea, Republic of
*Purpose: The risk of retinal vein occlusion(RVO) is known to increase in patients with chronic kidney disease, especially end-stage renal disease (ESRD). However, little is…
2020 American Transplant Congress
Determinants of Cardiovascular Benefit Observed in a Population with a Functioning Renal Transplant versus Patients Undergoing Chronic Dialysis
J. Sleiman, C. Castellaro, G. Laham, M. Schiavone, M. Biain, L. Brukman, G. Soler Pujol, C. Diaz
Nephrology, CEMIC, Caba, Argentina
*Purpose: Patients (pts) with end stage renal disease have a high morbidity and mortality rate, mostly due to cardiovascular events (CV). Transplantation (Tx) improves survival…
2019 American Transplant Congress
Identification and Determinants of Cardiac Allograft Vasculopathy Trajectories after Heart Transplantation
G. Bonnet¹, G. Coutance¹, M. Racape¹, M. Raynaud¹, J. Van keer², M. Bories¹, S. Varnous³, P. Rouvier³, R. Guillemain⁴, L. Lecuyer⁴, P. Bruneval⁴, J. Duong-Van-Huyen¹, J. Taupin⁵, M. Naesens², C. Lefaucheur¹, X. Jouven¹, A. Loupy¹
¹Paris Transplant Group, Paris, France, ²KU Leuven, Leuven, France, ³Pitie Salpetriere Hospital, Paris, France, ⁴Georges Pompidou Hospital, Paris, France, ⁵Saint Louis Hospital, Paris, France
*Purpose: CAV is a major contributor of heart transplant recipient’s mortality. However, little is known about CAV long-term evolution profiles and their determinants. Such information…
2019 American Transplant Congress
Impact of Simultaneous Pancreas-Kidney Transplantation on Cardiovascular Risk in Type 1 Diabetic Patients
E. Montagud-Marrahi
Servei de Nefrologia i Trasplantament Renal, Hospital Clínic de Barcelona, Barcelona, Spain
*Purpose: Cardiovascular disease is the main cause of death in patients with type 1 diabetes mellitus (DM1). Information available about the impact of simultaneous pancreas-kidney…
2019 American Transplant Congress
Cryopreserved Human Iliac Arteries Allografts: Different Thawing Rates Affect on Their Structural Changes and Mechanical Properties
R. Novotny¹, J. Chlupac¹, R. Matejka², T. Marada¹, P. Mericka³, L. Sterba³, L. Janousek¹, J. Fronek¹
¹Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²Department of Biomedical Engineerin, Faculty of Biomedical Engineering, Czech Technical University, Prague, Czech Republic, ³Tissue Bank, Faculty Hospital Hradec Kralove, Hradec Kralove, Czech Republic
*Purpose: The rate of thawing of cryopreserved human iliac arteries allografts (CHIAA) directly affects the severeness of structural changes that occur during this process. This…