Articles tagged "Vascular disease"

2020 American Transplant Congress
Late Onset Primary Graft Dysfunction after Lung Transplantation Correlates with Transplant Arteriosclerosis in a Humanized Mouse Model
M. Franz¹, T. Siemeni¹, A. Knöfel¹, W. Sommer¹, M. Avsar¹, F. Ius¹, I. Tudorache¹, C. Kühn¹, C. S. Falk², G. Warnecke¹, A. Haverich¹
¹Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, ²IFB-Tx, Hannover Medical School, Hannover, Germany
*Purpose: Primary Graft dysfunction (PGD) is one of the most important causes of early mortality after lung transplantation. We investigated the correlation between the incidence…
2020 American Transplant Congress
The Impact of Increased Visceral Fat in Kidney Transplant Recipients
Y. Miyauchi, T. Noda, N. Miura, T. Kikugawa, T. Saika
Ehime University, Toon, Japan
*Purpose: An increased amount of visceral fat (VF) has been reported as a precursor to metabolic syndrome and is a risk factor for renal dysfunction.…
2020 American Transplant Congress
Serum Osteopontin Level is Negatively Associated with Vascular Reactivity Index by Digital Thermal Monitoring in Kidney Transplant Patients
B. Hsu¹, Y. Lai¹, M. Lee²
¹Division of Nephrology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, ²Department of Surgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan
*Purpose: Osteopontin (OPN) is a potent inhibitor of mineralization and is a potent inducible inhibitor of vascular calcification. Studies in patients noted elevated levels of…
2020 American Transplant Congress
Lower Extremity Vascular Complications after Simultaneous Pancreas Kidney Transplant
H. J. Braun, D. Amara, T. Sorrentino, J. L. Ramirez, J. Lin, A. Mello, P. G. Stock, J. S. Hiramoto
University of California, San Francisco, San Francisco, CA
*Purpose: Type 1 diabetes mellitus (DM) is the leading indication for simultaneous pancreas kidney transplantation (SPK). Prior work has demonstrated a 2% incidence of lower…
2020 American Transplant Congress
The Role of mTOR Inhibitors on Cardiovascular Aging in Renal Transplanted Patients with Chronic Graft Dysfunction
G. Castellano¹, B. Infante¹, P. Pontrelli¹, R. Franzin¹, F. Rascio¹, C. Prisciandaro², L. Gesualdo¹, N. Coviello³, G. Grandaliano³, G. Stallone³
¹Emergency and Organ Transplantation, University of Bari, Bari, Italy, ²University of Foggia, Foggia, Italy, ³Emergency and Organ Transplantation, University of Foggia, Foggia, Italy
*Purpose: Chronic Kidney Disease (CKD) is strongly associated with increased circulatory complications that can lead to accelerated cardiovascular aging. During CKD, persistent oxidative stress triggered…
2020 American Transplant Congress
Unified Management of Inferior Vena Cava Web and Right Hepatic Vein in Living Donor Liver Transplantation for Membranous Obstruction of Vena Cava (Budd Chiari Syndrome)
Y. Nah, S. Park, E. Lee, S. Park
Department of Surgery, Ulsan University Hospital, Ulsan, Korea, Republic of
*Purpose: In Eastern countries Budd Chiari syndrome (BCS) is most often caused by the membranous obstruction of the vena cava (MOVC). During living donor liver…
2020 American Transplant Congress
Predominant Role of Microvascular Injury and Rarefaction Function as Drivers of Progressive Renal Damage and Fibrosis Post Mild and Severe Acute Ischemia-Reperfusion Injury
S. Lan¹, B. Yang¹, J. Sabo-Vatasescu², M. Bourgault², A. Karakeussian-Rimbaud³, J. Turgeon³, S. Qi¹, N. Patey⁴, M. Dieudé⁵, M. Hébert¹
¹Medicine Faculty, CRCHUM, CDTRP, University of Montreal, Montreal, QC, Canada, ²CRCHUM, Montreal, QC, Canada, ³CRCHUM, CDTRP, Montreal, QC, Canada, ⁴Medicine Faculty, CRCHUM, Saint Justine Hospital, University of Montreal, Montreal, QC, Canada, ⁵CRCHUM, CDTRP, University of Montreal, Montreal, QC, Canada
*Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor for chronic renal failure. Here, we characterize the different cell deaths in tubular and microvascular compartments…
2019 American Transplant Congress
Apoptotic Exosome-Like Vesicles Induce Endothelial Cell Plasticity and Accelerate Allograft Vascular Remodeling
F. Migneault¹, M. Dieudé¹, J. Turgeon¹, A. Karakeussian Rimbaud¹, D. Beillevaire¹, M. Hardy², A. Brodeur¹, N. Thibodeau¹, C. Perreault², M. Hébert¹
¹CRCHUM, Montreal, QC, Canada, ²IRIC, Montreal, QC, Canada
*Purpose: Acute vascular rejection of allografts is associated with endothelial apoptosis which in turn contributes to the development of transplant vasculopathy. We previously showed that…
2019 American Transplant Congress
Identification and Determinants of Cardiac Allograft Vasculopathy Trajectories after Heart Transplantation
G. Bonnet¹, G. Coutance¹, M. Racape¹, M. Raynaud¹, J. Van keer², M. Bories¹, S. Varnous³, P. Rouvier³, R. Guillemain⁴, L. Lecuyer⁴, P. Bruneval⁴, J. Duong-Van-Huyen¹, J. Taupin⁵, M. Naesens², C. Lefaucheur¹, X. Jouven¹, A. Loupy¹
¹Paris Transplant Group, Paris, France, ²KU Leuven, Leuven, France, ³Pitie Salpetriere Hospital, Paris, France, ⁴Georges Pompidou Hospital, Paris, France, ⁵Saint Louis Hospital, Paris, France
*Purpose: CAV is a major contributor of heart transplant recipient’s mortality. However, little is known about CAV long-term evolution profiles and their determinants. Such information…
2019 American Transplant Congress
Impact of Simultaneous Pancreas-Kidney Transplantation on Cardiovascular Risk in Type 1 Diabetic Patients
E. Montagud-Marrahi
Servei de Nefrologia i Trasplantament Renal, Hospital Clínic de Barcelona, Barcelona, Spain
*Purpose: Cardiovascular disease is the main cause of death in patients with type 1 diabetes mellitus (DM1). Information available about the impact of simultaneous pancreas-kidney…