Articles tagged "Vascular disease"

2021 American Transplant Congress
Coronary Computed Tomography Angiography for Pre-Liver Transplant Cardiovascular Risk Assessment: A Single Center Experience
J. Rice¹, T. Genders², D. Groves², J. R. Burton¹, J. Moloo², R. Quaife², D. Vargas³, M. Kriss¹
¹Division of Gastroenterology and Hepatology, University of Colorado, Aurora, CO, ²Division of Cardiology, University of Colorado, Aurora, CO, ³Division of Radiology, University of Colorado, Aurora, CO
*Purpose: Coronary computed tomography angiography (CCTA) is an established non-invasive imaging modality for diagnosing coronary artery disease (CAD), though its use for cardiovascular disease (CVD)…
2021 American Transplant Congress
Belatacept Conversion in Proteinuric Renal Transplant Recipients: An Interventional Multi-Center Trial
O. Efe¹, A. Al Jurdi¹, D. Wojciechowski², K. Safa¹, H. Gilligan¹, A. Chandraker³, J. Azzi³, A. Weins³, L. V. Riella¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, ²UT Southwestern Medical Center, Dallas, TX, ³Brigham and Women’s Hospital, Boston, MA
*Purpose: Proteinuria develops in about 30% of kidney transplant recipients and is a strong predictor of graft loss. ACEis/ARBs can reduce proteinuria but are frequently…
2021 American Transplant Congress
Comparative Outcomes of Endovascular Interventions for Hepatic Artery Stenosis Following Adult Liver Transplantation
S. Desai¹, D. Crabtree², A. Parsikia², R. Ahuja¹, A. Desai¹, B. Natarajan¹, P. Brady¹, H. Kaul³, K. Khanmoradi³, R. Zaki³, N. Chandolias³
¹Interventional Radiology, Albert Einstein Medical Center - Philadelphia, Philadelphia, PA, ²General Surgery, Albert Einstein Medical Center - Philadelphia, Philadelphia, PA, ³Transplant Surgery, Albert Einstein Medical Center - Philadelphia, Philadelphia, PA
*Purpose: There is mounting evidence supporting interventional radiology (IR) treatment for hepatic artery stenosis (HAS) following liver transplantation to improve diminutive graft perfusion and to…
2021 American Transplant Congress
Predictive Factors of the Hepatic Artery Thrombosis in Liver Transplantation Through the Analysis of Donor Characteristics
M. M. Pascale¹, G. Moschetta², G. Bianco², F. Frongillo², E. Nure², F. Giovinazzo², S. Agnes²
¹General Surgery and Liver Transplant Unit, Fondazione, Roma, Italy, ²General Surgery and Liver Transplant Unit, Fondazione "Policlinico A. Gemelli" UCSC - Rome, Roma, Italy
*Purpose: Hepatic artery thrombosis (HAT) is one of the most severe complications after liver transplantation. It is treated as soon as possible to avoid irreversible…
2020 American Transplant Congress
Serum Osteopontin Level is Negatively Associated with Vascular Reactivity Index by Digital Thermal Monitoring in Kidney Transplant Patients
B. Hsu¹, Y. Lai¹, M. Lee²
¹Division of Nephrology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, ²Department of Surgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan
*Purpose: Osteopontin (OPN) is a potent inhibitor of mineralization and is a potent inducible inhibitor of vascular calcification. Studies in patients noted elevated levels of…
2020 American Transplant Congress
Lower Extremity Vascular Complications after Simultaneous Pancreas Kidney Transplant
H. J. Braun, D. Amara, T. Sorrentino, J. L. Ramirez, J. Lin, A. Mello, P. G. Stock, J. S. Hiramoto
University of California, San Francisco, San Francisco, CA
*Purpose: Type 1 diabetes mellitus (DM) is the leading indication for simultaneous pancreas kidney transplantation (SPK). Prior work has demonstrated a 2% incidence of lower…
2020 American Transplant Congress
The Role of mTOR Inhibitors on Cardiovascular Aging in Renal Transplanted Patients with Chronic Graft Dysfunction
G. Castellano¹, B. Infante¹, P. Pontrelli¹, R. Franzin¹, F. Rascio¹, C. Prisciandaro², L. Gesualdo¹, N. Coviello³, G. Grandaliano³, G. Stallone³
¹Emergency and Organ Transplantation, University of Bari, Bari, Italy, ²University of Foggia, Foggia, Italy, ³Emergency and Organ Transplantation, University of Foggia, Foggia, Italy
*Purpose: Chronic Kidney Disease (CKD) is strongly associated with increased circulatory complications that can lead to accelerated cardiovascular aging. During CKD, persistent oxidative stress triggered…
2020 American Transplant Congress
Unified Management of Inferior Vena Cava Web and Right Hepatic Vein in Living Donor Liver Transplantation for Membranous Obstruction of Vena Cava (Budd Chiari Syndrome)
Y. Nah, S. Park, E. Lee, S. Park
Department of Surgery, Ulsan University Hospital, Ulsan, Korea, Republic of
*Purpose: In Eastern countries Budd Chiari syndrome (BCS) is most often caused by the membranous obstruction of the vena cava (MOVC). During living donor liver…
2020 American Transplant Congress
Predominant Role of Microvascular Injury and Rarefaction Function as Drivers of Progressive Renal Damage and Fibrosis Post Mild and Severe Acute Ischemia-Reperfusion Injury
S. Lan¹, B. Yang¹, J. Sabo-Vatasescu², M. Bourgault², A. Karakeussian-Rimbaud³, J. Turgeon³, S. Qi¹, N. Patey⁴, M. Dieudé⁵, M. Hébert¹
¹Medicine Faculty, CRCHUM, CDTRP, University of Montreal, Montreal, QC, Canada, ²CRCHUM, Montreal, QC, Canada, ³CRCHUM, CDTRP, Montreal, QC, Canada, ⁴Medicine Faculty, CRCHUM, Saint Justine Hospital, University of Montreal, Montreal, QC, Canada, ⁵CRCHUM, CDTRP, University of Montreal, Montreal, QC, Canada
*Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor for chronic renal failure. Here, we characterize the different cell deaths in tubular and microvascular compartments…
2020 American Transplant Congress
Age-Enhanced Transplant Vasculopathy Associates with Impaired Vascular Mitophagy
M. Blin¹, D. Tyrrell¹, S. Wood¹, D. Farris¹, S. G. Tullius², D. R. Goldstein¹
¹Micro and Immunology/Internal Medicine, University of Michigan, Ann Arbor, MI, ²Transplant Surgery, Brigham and Women's Hospital, Boston, MA
*Purpose: Donor aging leads to increased chronic allograft vasculopathy (CAV) for unclear reasons. Here, we investigated whether impaired alterations in mitophagy, a mechanism to remove…