ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Vascular disease"

  • 2022 American Transplant Congress

    Pre- Kidney Transplant Coronary Angiography Findings Based on Vascular Calcification on CT in Patients with a Negative Stress Test

    S. Valavoor, A. Sharfuddin, W. Goggins, M. Jan, O. Adebiyi, M. Yaqub

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Patients with ESRD or advanced CKD have higher incidence of coronary artery disease. We report coronary angiography findings in asymptomatic Pre Kidney transplant recipients…
  • 2022 American Transplant Congress

    Comparison of Cardiovascular Events by Different Types of Lipid-Lowering Drugs in Kidney Transplant Recipients

    S. Bae1, J. Ahn2, M. A. Schnitzler3, K. Lentine4, D. Segev1, M. McAdams-DeMarco1

    1Johns Hopkins University, Baltimore, MD, 2SOM, Johns Hopkins University, Baltimore, MD, 3Surgery, Saint Louis University, St. Louis, MO, 4Saint Louis University, St. Louis, MO

    *Purpose: Lipid-lowering drugs, notably statins, are one of the most widely prescribed drug classes in kidney transplant (KT) recipients. These drugs have substantially different mechanisms…
  • 2022 American Transplant Congress

    Low-Dose Aspirin is Effective in Preventing Transplant Renal Artery Stenosis: A Prospective Randomized Controlled Trial

    X. Tian, W. Duan, X. Niu, X. Wu, C. Zhang, J. Zhao, Z. Wang, G. Cao, B. Ji, Y. Gu, H. Cao, T. Qin, F. Shao, T. Yan

    Henan Provincial People's Hospital, Zhengzhou, Henan Province, China

    *Purpose: Transplant renal artery stenosis (TRAS), the most common post-transplant vascular complication, leads to resistant hypertension, renal impairment, and even graft loss. No effective prophylactic…
  • 2022 American Transplant Congress

    HDAC Inhibitors Suppress Endothelial Inflammation but Alter Identity

    N. M. Valenzuela

    Pathology and Laboratory Medicine, UCLA, Los Angeles, CA

    *Purpose: Histone modifications such as acetylation control gene expression. Histone deacetylases (HDACs) have been proposed as an attractive therapeutic approach to counteract detrimental gene expression,…
  • 2022 American Transplant Congress

    CT Based Iliac Vessel Calcification Scoring: Long Term Patient and Allograft Outcomes

    L. Clementoni, M. R. Akhtar, C. Seet, M. Saoud, R. Shah, I. H. Mohamed, M. A. Khurram

    The Royal London Hospital - Barts Health NHS Trust, London, United Kingdom

    *Purpose: Coronary calcification is a known indicator of poor cardiac outcomes. Similarly, iliac and distal vascular calcification has been shown to be an adverse outcome…
  • 2022 American Transplant Congress

    Impact of Changing Tacrolimus Formulation on Cerebral Blood Flow and Cognitive Function

    I. Mahaparn, R. Lepping, R. N. Montgomery, R. Mukherjee, S. Billinger, W. M. Brooks, A. Gupta

    University of Kansas Medical Center (KUMC), Kansas City, KS

    *Purpose: To assess if switching to extended release (ER) tacrolimus changes cerebral blood flow (CBF) or cognitive function after switching stable kidney transplant (KT) recipients…
  • 2022 American Transplant Congress

    Progression of Peripheral Vascular Disease After Kidney/Pancreas Transplantation

    R. J. Knight, E. A. Graviss, D. T. Nguyen, Y. Ye, S. G. Yi, C. S. Bavare, A. R. Sadhu, H. Podder, M. Hobeika, R. McMillan, A. O. Gaber

    Houston Methodist Hospital, Houston, TX

    *Purpose: It is unclear whether kidney/pancreas (KP) transplantation will prevent the progression of peripheral vascular disease in patients with IDDM and ESRD. We sought to…
  • 2022 American Transplant Congress

    Kidney Transplant Recipients Not Reaching the Expected Post-Transplant Creatinine Range Most Likely Show Calcineurin-Inhibitor Nephrotoxicity Upon Histology

    S. von Moos1, K. Valkova1, L. Matter1, T. F. Müller1, T. Schachtner2

    1University Hospital Zürich, Zürich, Switzerland, 2University Hospital Zurich, Zürich, Switzerland

    *Purpose: Very recently, our own data suggested that approximately 25% of deceased-donor kidney transplant recipients (KTRs) and 10% of living-donor KTRs don’t reach the expected…
  • 2021 American Transplant Congress

    Impact of Statin Intensity on the Incidence of Vascular Events and Graft Survival in Heart Transplant Recipients

    E. Kim1, I. Booth2, R. Madathil3, B. Ravichandran1, M. Demehin2, M. Plazak2

    1University of Maryland School of Pharmacy, Baltimore, MD, 2Pharmacy, University of Maryland Medical Center, Baltimore, MD, 3University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Cardiac allograft vasculopathy (CAV) limits long-term graft survival of heart transplant (HT) recipients. In addition to decreased synthesis of cholesterol, statins also demonstrate immunomodulatory…
  • 2021 American Transplant Congress

    Angiotensin II Type-1 Receptor Antibodies are Associated with Inferior Renal Allograft Survival

    P. Martin, E. Santos, N. Gunby, M. Willicombe

    Renal Department, Imperial College Healthcare NHS Trust, London, United Kingdom

    *Purpose: AT1R-antibodies have been implicated in antibody-mediated vascular rejection in the absence of detectable HLA donor specific antibody (DSA), in addition to cardiovascular diseases. Transplant…
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