ATC Abstracts

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Articles tagged "Urinalysis"

  • 2015 American Transplant Congress

    Urinary CXCL10 Independently Improves the Noninvasive Diagnosis of Antibody-Mediated Kidney Allograft Rejection

    M. Rabant,1,2 L. Amrouche,2,3 X. Lebreton,3 F. Aulagnon,3 A. Benon,2 V. Sauvaget,2 R. Bonifay,2 L. Morin,3 A. Scemla,3 M. Delville,3 F. Martinez,3 M. Timsit,4 J. Duong Van Huyen,1 C. Legendre,3 F. Terzi,2 D. Anglicheau.2,3

    1Pathology Department, Necker Hospital, Paris, France; 2INSERM U1151, Necker Hospital, Paris, France; 3Kidney Transplant Center, Necker Hospital, Paris, France; 4Urology Department, Necker Hospital, Paris, France.

    The urinary levels of CXCL9 and CXCL10 can noninvasively diagnose T cell-mediated rejection (TCMR) of renal allografts. Their performance as diagnostic/prognostic markers of antibody-mediated rejection…
  • 2015 American Transplant Congress

    Reduced Urinary Uromodulin (UMOD)-Levels Are associated With Urinary Tract Infections (UTI) After Renal Transplantion

    K. Stahl, J. Beneke, H. Haller, W. Gwinner, M. Schiffer.

    Nephrology, Hannover Medical School, Hannover, Germany.

    Background:Urinary tract infection (UTI) following renal transplantation remains the most common post transplant bacterial infection and appears to be closely linked to reduced allograft and…
  • 2015 American Transplant Congress

    Pre-Liver Transplant Urinary Proteome Analysis Does Not Predict Development of Chronic Kidney Disease After Transplantation

    D. Milongo,1,3 J. Bascands,2,3,4 L. Esposito,1,3 L. Lavayssière,1,3 A. Del Bello,1,3 L. Rostaing,1,3,5 J. Schanstra,2,3,4 N. Kamar.1,3,5

    1Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France; 3Université Toulouse III Paul-Sabatier, Toulouse, France; 4Plateau de Protéomique des Liquides Biologiques, Institut of Cardiovascular and Metabolic Disease, Toulouse, France; 5INSERM U1043, IFR–BMT, Toulouse, France.

    Background and aims: Chronic kidney disease (CKD) is a common complication after liver transplantation. Kidney biopsies cannot be easily performed before liver transplantation to predict…
  • 2015 American Transplant Congress

    Potential Urine Protein Biomarkers for Kidney Transplantation Dysfunction Through Quantitative Proteomics

    T. Sigdel,1 N. Salomonis,2 C. Nicora,3 J. He,3 W.-J. Qian,3 D. Camp,3 M. Sarwal.1

    1UCSF, San Francisco, CA; 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 3Pacific Northwest National Laboratory, Richland, WA.

    Introduction: Inability to effectively monitor transplant injuries leads to immune and non-immune mediated graft dysfunction. A non-invasive tool to monitor such injuries is an unmet…
  • 2015 American Transplant Congress

    A Non-Invasive Urinary Common Rejection Module (uCRM) Gene Expression Score Enables Accurate Discrimination of Acute Rejection in Kidney Transplant Patients

    O. Bestard,1,2 T. Sigdel,1 Y. Ng,1 S.-C. Hsieh,1 S. Roedder,1 N. Dvorak,1 T. Tran,1 M. Sarwal.1

    1Department of Transplant Surgery, UCSF, San Francisco, CA; 2Kidney Transplant Unit, Bellvitge University Hospital, Barcelona, CAT, Spain.

    A common rejection module (CRM) consisting of 11 genes expressed on allograft biopsies was recently shown to be highly accurate to discriminate patients undergoing acute…
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