ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Tumor recurrence"

  • 2018 American Transplant Congress

    Influence of Initial Tumor Burden and Wait Times on Post-Transplant Outcomes after Down-Staging of Hepatocellular Carcinoma (HCC)

    N. Mehta, J. Dodge, F. Yao.

    UCSF, San Francisco.

    Background: A new national policy has adopted the UNOS Region 5 down-staging protocol for liver transplant (LT) in HCC meeting the following inclusion criteria -…
  • 2018 American Transplant Congress

    Malignancy Complications after Kidney Transplantation, the Role of Immunosuppression

    M. Molina,1 J. Cabrera,2 E. Gonzalez,1 A. Hernández,1 N. Polanco,1 A. Andres.1

    1Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain; 2Nephrology Department, Hospital Evangelico, Montevideo, Uruguay.

    Introduction: Immunosuppression therapy is essential to avoid rejection after kidney transplantation. The chronic use of this drugs increases the risk of malignancy compared to general…
  • 2018 American Transplant Congress

    Prediction of Hepatocellular Carcinoma Recurrence Following Liver Transplantation Using Combined Differential Gene Expression, Copy Number Variation and Somatic Mutation Analysis

    A. Humar,1 P. Liu,2 J. Luo,3 M. Nalesnik,3 A. Singhi,3 G. Tseng,2 G. Michalopoulos.3

    1Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Biostatistics, University of Pittsburgh, Pittsburgh, PA; 3Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.

    Liver allocation for transplant candidates with hepatocellular carcinoma is limited by OPTN policy to patients whose tumors remain within size limits defined by Milan criteria.…
  • 2018 American Transplant Congress

    Neutrophil to Lymphocyte Ratio (NLR) Does Not Predict Outcomes after Liver Transplant (LT) for Hepatocellular Carcinoma (HCC)

    E. Harding-Theobald, N. Mehta, F. Yao.

    Hepatology, UCSF, San Francisco.

    Background: A high preoperative NLR ≥5 has been reported to predict poor outcomes following LT for HCC, and NLR has been incorporated into several prognostic…
  • 2017 American Transplant Congress

    Recurrent HCC After Radiofrequency Ablation or Liver Resection Can Be Effectively Treated with Salvage Transplantation.

    H. Muaddi,1 D. Al-Adra,1 J. Shaw,1 D. Grant,1 P. Greig,1 I. McGilvray,1 M. Cattral,1 A. Wei,1 C.-A. Moulton,1 J. Kachura,2 R. Beecroft,2 M. Selzner,1 A. Ghanekar,1 S. Gallinger,1 S. Cleary,1 G. Sapisochin.1

    1General Surgery, University of Toronto, Toronto, ON, Canada; 2Medical Imaging, University of Toronto, Toronto, ON, Canada

    Background:Liver resection (LR) and radiofrequency ablation (RFA) represent curative therapies for early stages of hepatocellular carcinoma (HCC). If tumour recurrence occurs, salvage liver transplant (SLT)…
  • 2017 American Transplant Congress

    Pre-TACE Immune Status Correlates with Treatment Response and Tumor Biology in HCC as a Bridge to Transplant.

    T. Sandow,1 H. Bohorquez,2 D. Kirsch,1 A. Albar,1 P. Thevenot,3 K. Nunez,3 D. DeVun,1 J. Gimenez,1 G. Galliano,4 A. Cohen,2 G. Loss,2 D. Kay,1 P. Gulotta.1

    1Radiology, Ochsner Clinic Foundation, New Orleans, LA; 2Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA; 3Institute of Translational Research, Ochsner Clinic Foundation, New Orleans, LA; 4Pathology, Ochsner Clinic Foundation, New Orleans, LA

    Purpose:Immune factors are pivotal against disease progression after transplant in hepatocellular carcinoma (HCC). With chemoembolization (TACE) as a bridge to liver transplant, this study compares…
  • 2017 American Transplant Congress

    Serum AFP Greater Than 200 ng/ml as a Predictor for Low Survival in Patients with Hepatocelullar Carcinoma Recurrence in a Brazilian Multicentric Study.

    I. Boin,1 M. Possatto,1 E. Ataide,1 R. Silva,2 R. Silva,2 H. Felicio,2 L. Amado,3 A. Lima,3 T. Seva-Pereira.1

    1Unit of Liver Transplantation, State University of Campinas, Campinas, SP, Brazil; 2Digestive Surgery - Liver Transplantation, Faculty of Medicine- São Jose do Rio Preto, Rio Preto, SP, Brazil; 3Digestive Surgery - Liver Transplantation, Faculty of Medicine, Federal University of Minas Gerais, Minas Gerais, Brazil

    Introduction: Liver transplantation (LT) is the only potential curative treatment for hepatocellular carcinoma (HCC) with recurrence (HCC-R) diagnosed in 16%. Aim: The objective of this…
  • 2017 American Transplant Congress

    Very Long Term Graft Survival. Forecasts Factors.

    S. Jimenez Alvaro, R. Marcen Letosa, A. Fernandez Rodriguez, S. Elias Treviño, C. Galeano Alvarez, F. Liaño Garcia.

    Nephrology, Hospital Ramon y Cajal, Madrid, Spain

    Introduction: Kidney transplantation is the best treatment for end-stage renal failure. Between 2 and 5% of transplanted grafts are lost each year and only a…
  • 2017 American Transplant Congress

    Impact of Polymorphisms of UGT 1 A9 on the Prognosis of Renal Transplant Patients. Association with Digestive Tumors.

    N. Calvo, I. Perez-Flores, A. Shabaka, M. Moreno, B. Rodriguez-Cubillo, J. Delgado, M. Calvo, A. Sanchez-Fructuoso.

    Nephrologist, Hospital Clinico San Carlos, Madrid, Spain

    The aim of this study was to evaluate the distribution of UGT1A9 promoter region T-275A and C-2152T single nucleotide polymorphisms (SNPs) in stable transplant patients…
  • 2017 American Transplant Congress

    HCV Eradication with DAA Therapy Should Be Attempted Prior to Liver Transplantation and Does Not Impact HCC Recurrence.

    J. Emamaullee, M. Bral, G. Meeberg, A. Montano-Loza, V. Bain, D. Bigam, N. Kneteman, A. Shapiro.

    University of Alberta, Edmonton, AB, Canada

    Background: Recent advances in the direct-acting antiviral (DAA) treatment of HCV have lead to high rates of HCV eradication, even in patients with decompensated cirrhosis.…
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