ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Tumor recurrence"

  • 2022 American Transplant Congress

    Degree of Pre-Liver Transplant Immune Dysfunction Correlates with Post-Transplant Cancer Recurrence

    G. S. Prakash1, G. G. Panayotova1, S. Simonishvili1, Y. Qin1, L. Jin1, T. Ayorinde1, L. J. Minze2, F. Paterno1, L. Brown1, A. Amin1, D. Liu1, R. Ghobrial2, J. V. Guarrera1, K. E. Lunsford1

    1Rutgers New Jersey Medical School, Newark, NJ, 2Houston Methodist Hospital, Houston, TX

    *Purpose: Despite stringent selection criteria for liver transplant (LT) in patients with liver-limited malignancy, post-transplant cancer recurrence remains problematic. We have previously identified a pre-LT…
  • 2022 American Transplant Congress

    Clinical Efficacy of Adjuvant Immunotherapy for Liver Transplant Recipients with Exceeding Japan Criteria of Hepatocellular Carcinoma Using Donor Liver Derived Natural Killer Cells

    M. Ohira1, Y. Imaoka2, K. Sato3, K. Imaoka1, N. Tanimine1, H. Tahara1, K. Ide1, T. Kobayashi1, Y. Tanaka1, A. G. Tzakis4, S. Nishida5, H. Ohdan1

    1Hiroshima University, Hiroshima, Japan, 2Hiroshima Uni., Hiroshima, Japan, 3Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan, 4Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, OH, 5Univ of Miami School of Medicine, Valhalla, NY

    *Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
  • 2022 American Transplant Congress

    Induction Immunosuppression Does Not Worsen Tumor Recurrence After Liver Transplantation for T2 Hepatocellular Carcinoma and May Allow for Decreased Mortality

    C. Durkin1, T. Bittermann1, D. E. Schaubel2

    1Gastroenterology, University of Pennsylvania, Philadelphia, PA, 2Biostatistics, University of Pennsylvania, Philadelphia, PA

    *Purpose: Prior studies have suggested that induction therapy leads to worse outcomes after liver transplantation (LT) for hepatocellular carcinoma (HCC). This study evaluated the impact…
  • 2022 American Transplant Congress

    Mortality in Solid Organ Transplant Recipients with a Pretransplant Cancer Diagnosis

    A. Hart1, R. Pfeiffer2, B. Morawski3, C. Lynch4, Y. Zeng5, K. Pawlish6, K. Yu7, D. Hurley8, E. Engels7

    1Hennepin Healthcare, University of Minnesota, Minneapolis, MN, 2Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 3Cancer Registry of Idaho, Boise, ID, 4Epidemiology, University of Iowa, Iowa City, IA, 5North Dakota Statewide Cancer Registry, Grand Forks, ND, 6New Jersey State Cancer Registry, Trenton, NJ, 7Infections and Immunoepidemiology Branch, National Cancer Institute, Bethesda, MD, 8University of South Carolina, Columbia, SC

    *Purpose: Transplant-associated immunosuppression may cause cancer recurrence in patients with a pretransplant cancer, but little is known about outcomes among these recipients.*Methods: We used data…
  • 2022 American Transplant Congress

    Prevalence and Clinical Significance of Pancreatic Cystic Lesions in Immunosuppressed Patients with Solid Organ Transplantation

    Y. Yu, H. Jo, Y. Choi, J. Lee, D. Kim

    HBP surgery and liver transplantation, Korea University College of Medicine and School of Medicine, Seoul, Korea, Republic of

    *Purpose: Solid organ transplant recipients have an increased risk of cancer due to immunosuppressive therapy. Pancreatic cystic lesions (PCLs) are increasingly being detected, some with…
  • 2022 American Transplant Congress

    Everolimus in Liver Transplantation for Diffuse, Unresectable Neuroendocrine Tumor

    J. M. Vanatta1, R. A. Helmick2, C. Eymard2, N. Nezakatgoo2, P. Horton2, J. P. Kothadia2, S. P. Nair2, J. D. Eason2

    1Transplantation, University of Tennessee/Methodist University Hospital, Memphis, TN, 2Transplantation, University of Tennessee, Memphis, TN

    *Purpose: Liver transplantation (LT) has emerged as a therapy in selected patients for neuroendocrine tumor (NET) by providing cytoreduction. Progression-free survival in NET has been…
  • 2022 American Transplant Congress

    Atherosclerosis Reduces Anti-Tumor Activity of Liver-Resident Natural Killer Cells

    K. Imaoka, M. Ohira, K. Sato, Y. Imaoka, R. Nakano, H. Ohdan

    Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

    *Purpose: Abdominal aorta calcification (AAC) is associated with an increased relative risk of coronary events, cerebrovascular events, cardiovascular events, and cardiovascular death. We report that…
  • 2021 American Transplant Congress

    Adjuvant Immunotherapy for Liver Transplant Recipients with Hepatocellular Carcinoma Using Donor Liver-derived Natural Killer Cells

    M. Ohira1, R. Hotta1, Y. Imaoka1, K. Sato1, N. Tanimine1, Y. Tanaka1, S. Nishida2, A. Tzakis2, H. Ohdan1

    1Hiroshima University, Hiroshima, Japan, 2University of Miami, Miami, FL

    *Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and is an indication for liver transplantation (LT). Immunosuppressive regimens currently used after…
  • 2021 American Transplant Congress

    Living Donor Liver Transplant for Unresectable Colorectal Metastasis: A Case Series

    B. Emmanuel, H. Al-Harakeh, A. Humar, C. Hughes, A. Tevar, M. Molinari, A. Ganoza

    Starzl Transplant Institute, UPMC, Pittsburgh, PA

    *Purpose: Colorectal Cancer (CRC) represents the third most common malignancy worldwide. In the US, CRC lifetime risk is approximately 1 in 23 (4.4%) for men…
  • 2021 American Transplant Congress

    Outcomes of Liver Transplantation for Combined Hepatocellular Cholangiocarcinoma: A Single-center Experience

    Y. Liu1, C. Hanlon1, S. Zhou1, D. Toy1, K. King2, K. Zhou3, J. Kahn3, L. Yuan3

    1Internal Medicine, USC Keck School of Medicine, Los Angeles, CA, 2Radiology, USC Keck School of Medicine, Los Angeles, CA, 3Internal Medicine - Gastrointestinal and Liver Disease, USC Keck School of Medicine, Los Angeles, CA

    *Purpose: Combined hepatocellular cholangiocarcinoma (cHCC-CCA) is a hepatic tumor that exhibits histological features of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). cHCC-CCA is often diagnosed…
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