Articles tagged "Survival"

2022 American Transplant Congress
Internal Validation of a Pre-Transplant Biomarker Panel to Predict Post-Transplant Mortality: The Liver Immune Frailty Index
G. G. Panayotova¹, D. T. Nguyen², E. A. Graviss², L. J. Minze², S. Simonishvili¹, Y. Qin¹, T. Ayorinde¹, G. Prakash¹, F. Paterno¹, L. Brown¹, A. Amin¹, X. C. Li², R. M. Ghobrial², J. V. Guarrera¹, K. E. Lunsford¹
¹Rutgers New Jersey Medical School, Newark, NJ, ²Houston Methodist Hospital, Houston, TX
*Purpose: Infection and sepsis are the greatest contributors to early post-liver transplant (LT) mortality. These often result from ongoing immune dysfunction, or “Immune Frailty”. We…
2022 American Transplant Congress
Immunosuppressant Medications Use in Patients with Transplant Failure: A Canadian Multi-Centre Prospective Study
G. Knoll¹, M. Chassé², D. Fergusson³, A. A. House⁴, O. Johnston⁵, R. Mainra⁶, D. Baran⁷, D. Treleaven⁸, l. senecal⁹, L. Tibbles¹⁰, M. Hebert¹¹, M. Karpinski¹², T. Campbell¹³, T. Ramsay¹⁴, J. Kim¹⁵, I. Houde¹⁶, C. White¹⁷, J. Perl¹⁵, P. Karnabi¹⁸, J. Gill⁵
¹Nephrology, Ottawa Hospital Research Institute, Ottawa, ON, Canada, ²University of Montreal, Montreal, QC, Canada, ³Ottawa Hospital Research Institute, Ottawa, ON, Canada, ⁴Nephrology, Western University, London, ON, Canada, ⁵Nephrology, University of British Columbia, Vancouver, BC, Canada, ⁶Nephrology, University of Saskatchewan, Saskatoon, SK, Canada, ⁷Nephrology, McGill University, Montreal, QC, Canada, ⁸Nephrology, McMaster University, Hamilton, ON, Canada, ⁹Nephrology, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada, ¹⁰Nephrology, University of Calgary, Calgary, AB, Canada, ¹¹Nephrology, University of Montreal, Montreal, QC, Canada, ¹²Nephrology, University of Manitoba, Winnipeg, MB, Canada, ¹³University of Alberta, Alberta, AB, Canada, ¹⁴Ottawa Hospital Research Institute, Ottawa, ON, Canada, ¹⁵University of Toronto, Toronto, ON, Canada, ¹⁶Laval University, Que´bec, QC, Canada, ¹⁷Queen's University, Kingston, ON, Canada, ¹⁸Ottawa Health Research Institute, Ottawa, ON, Canada
*Purpose: This prospective study determined the association of immunosuppressant medication use with the outcomes of death, hospitalized infection, rejection of the failed allograft, and panel…
2022 American Transplant Congress
Outcomes in Kidney Transplant Recipients 70 Years and Older
J. Mehta, N. F. Okonkwo, A. Paramesh, K. Atiemo, M. Killackey, H. Jeon, A. Vijay
Tulane University School of Medicine, New Orleans, LA
*Purpose: Patients older than 70 years are the fastest-growing age group of patients requiring renal replacement therapy. This has resulted in a corresponding increase in…
2022 American Transplant Congress
Impact of Long Agonal Duration on Outcomes After Donation After Circulatory Death Lung Transplantation: An Analysis of the United Network of Organ Sharing Database
J. Thomas, Q. Chen, J. Chikwe, D. Emerson, D. Megna, P. Catarino
Department of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Lung transplantation (LTx) using donation after circulatory death (DCD) donors has been well established, however, previous investigators have focused on time from withdrawal of…
2022 American Transplant Congress
The High Acuity Index: A Posttransplant Prediction Score for High-MELD Patients
C. R. Christmann¹, A. Anand¹, G. Handing¹, A. Rana²
¹School of Medicine, Baylor College of Medicine, Houston, TX, ²Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Patients with a very high Model for End-Stage Liver Disease (MELD) score are at significant short-term risk for death without liver transplantation. While many…
2022 American Transplant Congress
Alloimmunization Against Red Blood Cell Antigens is Not Associated with Increased All Cause Mortality in Liver Transplant Recipients
Y. Chornenkyy¹, A. P. Gama¹, N. Khurram¹, A. L. Booth¹, J. R. Leventhal², G. E. Ramsey¹, G. Yang¹
¹Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: Liver transplantation (LT) is a life‐saving procedure for patients with end‐stage liver disease and transfusion therapy of LT patients remains a challenge. Improvement of…
2022 American Transplant Congress
Failure to Account for Social Determinants of Health in Non-HCC MELD Exceptions Exacerbates Geographic Disparities in Access to Liver Transplantation
R. M. Cannon, P. MacLennan, S. S. Sheikh, B. J. Orandi, A. Nasell, J. T. Walker, J. E. Locke
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Non-HCC MELD exceptions have been previously shown to give excess priority for transplant in certain UNOS Regions, but this phenomenon has not been examined…
2022 American Transplant Congress
Outcomes in Pediatric Intestinal Retransplantation
E. J. Lee¹, G. Mazariegos¹, K. Soltys¹, G. Bond¹, A. Ganoza¹, J. Rudolph², S. Horslen², R. Sindhi¹, A. Khanna¹
¹Transplant Surgery, UPMC, Pittsburgh, PA, ²Division of Gastroenterology, Hepatology and Nutrition,, UPMC, Pittsburgh, PA
*Purpose: Historically, intestinal retransplantation (Re-ITx) has been associated with high morbidity and mortality.*Methods: Retrospective chart review of patients who underwent Re-ITx at our institution between…
2022 American Transplant Congress
Survival Benefit of Preemptive Simultaneous Pancreas Kidney Transplantation
E. Montagud-Marrahi¹, E. Cuadrado-Payán¹, E. Hermida¹, D. Cucchiari¹, I. Revuelta¹, J. Del Risco-Zevallos¹, J. Casals¹, N. Esforzado¹, F. Cofan¹, F. Oppenheimer¹, V. Torregrosa¹, J. Ferrer², A. J. Amor³, E. Esmatjes¹, M. Ramirez-Bajo⁴, M. Musquera⁵, B. Bayés¹, J. Campistol¹, F. Diekmann¹, P. Ventura-Aguiar¹
¹Nephrology and Kidney Transplantation Department, Hospital Clínic of Barcelona, Barcelona, Spain, ²Hepatobiliopancreatic and Liver Transplant Department, Hospital Clínic of Barcelona, Barcelona, Spain, ³Diabetes Unit. Endocrinology and Nutrition Department, Hospital Clínic of Barcelona, Barcelona, Spain, ⁴Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació Clínic per a la Recerca, Hospital Clínic of Barcelona, Barcelona, Spain, ⁵Urology Department, Hospital Clínic of Barcelona, Barcelona, Spain
*Purpose: Diabetes mellitus is a well-established risk factor for morbidity and mortality among patients on dialysis, but the evidence regarding the benefits of performing preemptive…
2021 American Transplant Congress
Donor-Recipient BSA Matching is Prognostically Significant in Solitary and En-bloc Kidney Transplantation from Pediatric Circulatory Death Donors
C. J. Little, A. A. Dick, J. D. Perkins, J. D. Reyes
Department of Surgery, University of Washington, Seattle, WA
*Purpose: The purpose of this study was to evaluate the pernicious effects of inadequate functional nephron mass in size disparate donation after cardiac death (DCD)…

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