Articles tagged "Survival"

2017 American Transplant Congress
The Benefits of Pancreas After Kidney (PAK) Transplantation.
M. Curry,¹ J. Odorico,² J. Fridell.³
¹Research, UNOs, Richmond, VA; ²Department of Surgery, University of Wisconsin, Madison, WI; ³Department of Surgery, Indiana University, Indianpolis, IN
Background: PAK transplantation has been perceived as inferior to Simultaneous Pancreas and Kidney (SPK) transplantation with respect to patient and pancreas (PA) allograft survival. However,…
2017 American Transplant Congress
Impact of a B-Cell Targeting Agent on Antibody Mediated Rejection and Graft' Survival in Liver Transplantation with Preformed DSAs.
A. Del Bello,¹ V. Dubois,² J. Dumortier,³ N. Congy-Jolivet,⁴ N. Kamar.¹
¹Nephrology and Organ Transplant Department, CHU Toulouse, Toulouse, France; ²Department of Immunology, CHU Lyon, Lyon, France; ³Gastroenterology and Liver Transplant Department, CHU Lyon, Lyon, France; ⁴Department of Immunology, CHU Toulouse, Toulouse, France
Introduction The negative impact of preformed anti-HLA donor specific antibodies (DSAs) in liver transplantation is clearly established. However, the potential interest of a B-cell depleting…
2017 American Transplant Congress
Third Liver Transplantation, Outcomes, and the Impact of Previous Graft Survival.
M. Barry,¹ M. Gupta,² D. Goldberg,³ M. Levine,² D. Simpson,² K. Olthoff,² A. Shaked,² P. Abt.²
¹School of Medicine, University of Pennsylvania, Philadelphia, PA; ²Surgery, Division of Transplantation, University of Pennsylvania, Philadelphia, PA; ³Medicine, Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA
Introduction: Retransplantation with a third liver allograft is controversial with significant technical and medical challenges. National outcomes have not been described. We hypothesize that prior…
2017 American Transplant Congress
Survival Benefit of Kidney and/or Pancreas Transplantation for Patients with Type 1 Diabetes in the United States.
R. Gruessner,¹ M. Laftavi,¹ O. Pankowycz,² V. Whittaker,¹ Z. Acun,¹ V. Aggarwal,² N. Ozden,² A. Gruessner.¹
¹Surgery, SUNY Upstate Medical University, Syracuse, NY; ²Internal Medicine, SUNY Upstate Medical University, Syracuse, NY
Study Purpose: The purpose of this study was to determine the survival benefit of pancreas and/or kidney transplants as reported over a 28-year time period…
2017 American Transplant Congress
Is the Current Heart Allocation System Just and Fair for Blood Type O Recipients? – A Propensity-Matched Analysis of 34353 Patients in the UNOS Registry.
M. Ando, K. Takeda, P. Kurlansky, M. Wright, C. Lee, J. Han, A. Garan, V. Topkara, M. Yuzefpolskaya, P. Colombo, M. Farr, Y. Naka, H. Takayama.
Columbia University Medical Center, New York, NY
Purpose: There is a known disparity between the waiting time on heart transplant (HTx) between blood type O and non-O recipients. This difference is mainly…
2017 American Transplant Congress
Glucocorticoid Receptor – Relaxin Signaling in Liver Transplant Ischemia-Reperfusion Injury (IRI): From Bench-to-Bedside.
S. Kageyama,¹ K. Nakamura,¹ R. Sossa,² E. Reed,² N. Datta,¹ A. Zarrinpar,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹The Dumont-UCLA Transplant Center, Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles, CA; ²Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA
Background: Glucocorticoid receptor (GR) serves as a receptor for relaxin (RLX), a pregnancy hormone, with novel vasoactive and tissue remodeling properties. A phase III clinical…
2017 American Transplant Congress
Extending the Limit for Living Donor Liver Transplantation: Similar Outcomes After Left vs. Right Lobe Graft, a Propensity Score Analysis.
T. Wong, K. Ng, J. Fung, K. Chok, A. Chan, C. Lo.
Surgery, The University of Hong Kong, Hong Kong, Hong Kong
BackgroundThis study aimed to investigate the impact of graft selection (left vs. right lobe) in LDLT.MethodThis was a retrospective study that included all patients who…
2017 American Transplant Congress
Does Pancreas Transplantation for the Patients with Diabetes Showed Significant Survival Benefit?
J. Choi, J. Jung, S. Chun, S. Shin, Y. Kim, D. Han.
Department of General Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Background : Pancreas transplantation was considered a therapeutic option for patients with complicated DM. However, in the past decade, the annual number of PT performed…
2017 American Transplant Congress
Clinical Evaluation of the Safety and Preliminary Efficacy of Continuous Infusion of Treprostinil to Prevent Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplant Recipients.
O. Almazroo,¹ M. Miah,¹ V. Pillai,¹ A. Humar,² A. Tevar,² C. Hughes,² A. AlKhafaji,³ A. Demetris,⁴ S. Dermont,² S. Fedorek,² H. Johnson,¹ R. Lopez,² R. Planinsic,² B. Sengupta,² I. Sethu,² M. Sturdevant,² S. Ziobert,¹ R. Venkataramanan.^1,2,4
¹Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA; ²Thomas Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; ³Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA; ⁴Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA
Introduction:Liver transplantation is currently the only therapeutic option for patients with end stage liver diseases. Liver allografts undergo cold ischemic injury and warm reperfusion injury…
2017 American Transplant Congress
Risk Factors and Consequences of De Novo Anti-HLA Donor Specific Antibodies in Kidney Transplant Recipients: The Force Awakens.
B. Javaid, S. Rosen-Bronson, D. Li, M. Awwad, A. Gilbert, S. Ghasemian, J. Verbesey, P. Abrams, M. Grafals, J. Fenton, C. Cannon, J. Rapisura, J. Moore, M. Cooper.
Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Georgetown University School of Medicine, Washington, DC
Background: Presence of anti-HLA donor specific antibodies (DSAs) has been associated with inferior kidney transplant outcomes. Identification of risk factors for de novo DSAs could…