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Articles tagged "Risk factors"

  • 2015 American Transplant Congress

    UNOS KDPI Score Is Significantly Overestimated for Pediatric En-Bloc Kidneys

    L. Preczewski, K. Howes, N. Iovenette, A. Needham, B. Gallay.

    Transplant Center, University of California, Davis, Sacramento, CA.

    When Rao, et al, published the Kidney Donor Risk Index model (KDRI) (Transplantation 2009;88:231-236), they found coefficients for HLA match, cold ischemic time, en-bloc (EB)…
  • 2015 American Transplant Congress

    Cumulative Incidence, Risk Factors for and Impact on Survival of Severe Chronic Kidney Disease After Intestinal Transplantation: Analysis of the SRTR Database

    G. Huard,1 K. Iyer,1 J. Moon,1 L. Schwartz,1 J. Doucette,2 V. Nair,1 T. Schiano.1

    1Recanati-Miller Transplant Institute, Mount Sinai Hospital, New York, NY; 2Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.

    Background: Patient and graft survival rates after intestinal transplantation (ITx) have improved. More ITx recipients achieve long-term survival and are at risk for severe chronic…
  • 2015 American Transplant Congress

    High Within-Patient Variability in Tacrolimus Levels Is a Predictor of Late Rejection in Young Adult Kidney Transplant Recipients

    J. van der Net, P. Harden.

    Oxford Transplant Centre / Kidney Unit, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.

    Introduction: Non-adherence is an important risk factor for late rejection (rejection > 3 months post-transplant) and is the main reason why 17-29 year old kidney…
  • 2015 American Transplant Congress

    Risk Factors for Infections After Transplant in a Prospective Cohort Study Including Incompatible Kidney Transplant Recipients

    R. Avery,1 H.-L. Tsai,2 C.-Y. Huang,2 S. Shoham,1 D. Ostrander,1 N. Lu,1 R. Montgomery,3 K. Marr.1

    1Infectious Disease, Johns Hopkins, Baltimore, MD; 2Biostatistics and Bioinformatics, Johns Hopkins, Baltimore, MD; 3Transplant Surgery, Johns Hopkins, Baltimore, MD.

    Background: Infectious morbidity is a cumulative function of recurrent events. Historically, data collection has depended on time-to-event analyses, variable definitions, and retrospective data. To better…
  • 2015 American Transplant Congress

    Intrapatient Variability of Tacrolimus Blood Concentrations Following Renal Transplant – Acute Rejection or No Connection?

    D. Katarey,1,2 E. Ioannou,2 I. MacPhee.1,2

    1Renal Medicine, St George's Hospital, London, United Kingdom; 2St George's University of London, London, United Kingdom.

    Background: A high degree of intrapatient variability (IPV) of tacrolimus blood concentrations has been associated with poor long-term outcome (1). Periods of under-exposure with increased…
  • 2015 American Transplant Congress

    Examining Long-Term Survivors in Combined Heart-Lung Transplantation

    S. Kadakia,1 S. Jayarajan,1 S. Taghavi,1 V. Ambur,1 C. Lewis,1 A. Shiose,2 G. Wheatley III,2 L. Kaiser,3 T. Guy,2 Y. Toyoda.2

    1Department of Surgery, Temple University Hospital, Philadelphia, PA; 2Division of Cardiovascular Surgery, Temple University Hospital, Philadelphia, PA; 3Division of Thoracic Surgery, Temple University Hospital, Philadelphia, PA.

    The goal of this study was to determine variables associated with mortality in combined heart-lung transplantation (HLT).The United Network for Organ Sharing (UNOS) database was…
  • 2015 American Transplant Congress

    Characteristics and Consequences of Renal Allograft Rejections Due to Nonadherence

    S. Patel, S. Kuten, J. Everett, J. Loucks-DeVos, L. Gaber, A. Gaber, R. Knight.

    Houston Methodist Hospital, Houston.

    Non-adherence (NA) with immunosuppressive medications is associated with increased healthcare costs, rejection risk, and graft loss. NA is difficult to measure, however, and is often…
  • 2015 American Transplant Congress

    Increased Late Graft Loss in Kidney Recipients With Serum Sickness Disease Following Anti-Thymocyte Globulin Induction: Relation With an Anti-Neu5Gc Response

    A. Salama,1,2 G. Couvrat-Desvergnes,1 M. Lorent,1,3 G. Evanno,1 L. Le Berre,1 P. Hruba,4 P. Vesely,5 P. Guerif,1 A. Nicot,1 J.-M. Bach,6 Y. Foucher,1,3 S. Brouard,1 S. Castagnet,7 O. Viklicky,4 M. Giral,1 J. Harb,1 S. Jean-Paul.1

    1INSERM UMR 1064, ITUN, CHU de Nantes, Nantes University, Nantes, France; 2Société d'Accélération du Transfert de Technologies Ouest Valorisation, Rennes, France; 3EA 4275 SPHERE, Biostatistics, Clinical Research and Pharmaco-Epidemiology, Nantes, France; 4Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 5Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic; 6IECM, EA4644 University/ONIRIS USC1383 INRA, ONIRIS, Nantes, France; 7EFS Pays de la Loire, Nantes, France.

    Anti-thymocyte globulins (ATG) are rabbit IgGs against human T cells widely used as induction treatment of kidney recipients. ATG can induce immune-complex diseases including Serum…
  • 2015 American Transplant Congress

    Return to Work and Occupational Infection Risks in Transplant Recipients

    R. Avery,1 D. Ostrander,1 S. Shoham,1 S. Alp,2 N. Lu,1 C. Cave,1 E. Kraus,3 K. Marr.1

    1Infectious Disease, Johns Hopkins, Baltimore, MD; 2Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey; 3Nephrology, Johns Hopkins, Baltimore, MD.

    Background: Counseling is commonly provided to transplant recipients who are planning to return to work, regarding potential infection risks in the workplace. However, the nature…
  • 2015 American Transplant Congress

    Risk Factors for Graft Loss in Pediatric Renal Transplant Recipients After Transfer of Care

    B. Coyne,1,2 P. Hollen,1,2 Y. Guofen,3 K. Brayman.4

    1Department of Pediatrics, University of Virginia Health System, Charlottesville, VA; 2School of Nursing, University of Virginia, Charlottesville, VA; 3Department of Public Health Sciences, University of Virginia Health System, Charlottesville, VA; 4Department of Surgery, University of Virginia Health System, Charlottesville, VA.

    Improvements in immunosuppression and transplant surgical technique have increased the survival of children with end-stage renal disease. These patients have complex needs, and the current…
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