Articles tagged "Risk factors"

2015 American Transplant Congress
Increased Late Graft Loss in Kidney Recipients With Serum Sickness Disease Following Anti-Thymocyte Globulin Induction: Relation With an Anti-Neu5Gc Response
A. Salama,^1,2 G. Couvrat-Desvergnes,¹ M. Lorent,^1,3 G. Evanno,¹ L. Le Berre,¹ P. Hruba,⁴ P. Vesely,⁵ P. Guerif,¹ A. Nicot,¹ J.-M. Bach,⁶ Y. Foucher,^1,3 S. Brouard,¹ S. Castagnet,⁷ O. Viklicky,⁴ M. Giral,¹ J. Harb,¹ S. Jean-Paul.¹
¹INSERM UMR 1064, ITUN, CHU de Nantes, Nantes University, Nantes, France; ²Société d'Accélération du Transfert de Technologies Ouest Valorisation, Rennes, France; ³EA 4275 SPHERE, Biostatistics, Clinical Research and Pharmaco-Epidemiology, Nantes, France; ⁴Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; ⁵Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic; ⁶IECM, EA4644 University/ONIRIS USC1383 INRA, ONIRIS, Nantes, France; ⁷EFS Pays de la Loire, Nantes, France.
Anti-thymocyte globulins (ATG) are rabbit IgGs against human T cells widely used as induction treatment of kidney recipients. ATG can induce immune-complex diseases including Serum…
2015 American Transplant Congress
Risk Factors for Infections After Transplant in a Prospective Cohort Study Including Incompatible Kidney Transplant Recipients
R. Avery,¹ H.-L. Tsai,² C.-Y. Huang,² S. Shoham,¹ D. Ostrander,¹ N. Lu,¹ R. Montgomery,³ K. Marr.¹
¹Infectious Disease, Johns Hopkins, Baltimore, MD; ²Biostatistics and Bioinformatics, Johns Hopkins, Baltimore, MD; ³Transplant Surgery, Johns Hopkins, Baltimore, MD.
Background: Infectious morbidity is a cumulative function of recurrent events. Historically, data collection has depended on time-to-event analyses, variable definitions, and retrospective data. To better…
2015 American Transplant Congress
Intrapatient Variability of Tacrolimus Blood Concentrations Following Renal Transplant – Acute Rejection or No Connection?
D. Katarey,^1,2 E. Ioannou,² I. MacPhee.^1,2
¹Renal Medicine, St George's Hospital, London, United Kingdom; ²St George's University of London, London, United Kingdom.
Background: A high degree of intrapatient variability (IPV) of tacrolimus blood concentrations has been associated with poor long-term outcome (1). Periods of under-exposure with increased…
2015 American Transplant Congress
Determinants and Sequelae of Hepatic Artery Thrombosis After Liver Transplantation: A Registry Study of Recipient Diagnosis and Coagulopathy
J. Garonzik Wang,¹ M. Doyle,¹ K. Collins,¹ J. Lowell,¹ Y. Lin,¹ S. Shenoy,¹ J. Wellen,¹ W. Chapman,¹ D. Segev.²
¹Washington University, Barnes Jewish Hospital, Saint Louis, MO; ²Johns Hopkins University, Johns Hopkins Hospital, Baltimore, MD.
Hepatic artery thrombosis (HAT) is a dreaded complication following liver transplantation. Despite improvements in technique and procurement, HAT still occurs in approximately 2-5% of recipients.…
2015 American Transplant Congress
Incidence and Outcomes of Polyomavirus Infection in 639 Kidney Transplant Recipients: Are High Immunological Risk Characteristics More Relevant Than Specific Induction Or Maintenance Immunosuppressive Regimens?
E. Favi,¹ L. Harris,² J. Worsfold,² R. Cacciola,¹ C. Puliatti,¹ C. Sammartino,¹ R. Sivaprakasam.¹
¹Transplantation, Royal London Hospital, London, United Kingdom; ²Barts and The London School of Medicine and Dentistry, London, United Kingdom.
Introduction. Polyomavirus-associated nephropathy (PVAN) is now recognized as an important cause of graft dysfunction and early kidney transplant loss. Over-immunosuppression is the main risk factor…
2015 American Transplant Congress
Acute Kidney Injury in Kidney Transplant Patients According to the KDIGO Criteria
T. Filiponi, A. Silva-Filho, E. Tonato, L. Requiao-Moura, A. Matos, E. Arruda, R. Chinen, L. Pires, M. Durão Junior.
Kidney Transplantation, Albert Einstein Hospital, Sao Paulo, Brazil.
Purpose.To assess the incidence, risk factors and outcomes associated with acute kidney injury (AKI) in kidney transplant in patients using KDIGO classification. Methods- Retrospective cohort…
2015 American Transplant Congress
Return to Work and Occupational Infection Risks in Transplant Recipients
R. Avery,¹ D. Ostrander,¹ S. Shoham,¹ S. Alp,² N. Lu,¹ C. Cave,¹ E. Kraus,³ K. Marr.¹
¹Infectious Disease, Johns Hopkins, Baltimore, MD; ²Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey; ³Nephrology, Johns Hopkins, Baltimore, MD.
Background: Counseling is commonly provided to transplant recipients who are planning to return to work, regarding potential infection risks in the workplace. However, the nature…
2015 American Transplant Congress
Risk Factors for Graft Loss in Pediatric Renal Transplant Recipients After Transfer of Care
B. Coyne,^1,2 P. Hollen,^1,2 Y. Guofen,³ K. Brayman.⁴
¹Department of Pediatrics, University of Virginia Health System, Charlottesville, VA; ²School of Nursing, University of Virginia, Charlottesville, VA; ³Department of Public Health Sciences, University of Virginia Health System, Charlottesville, VA; ⁴Department of Surgery, University of Virginia Health System, Charlottesville, VA.
Improvements in immunosuppression and transplant surgical technique have increased the survival of children with end-stage renal disease. These patients have complex needs, and the current…
2015 American Transplant Congress
Tobacco Use Is a Significant Risk Factor for Post-Transplant Biliary Complications
D. Dulaney, M. Dokus, M. Orloff, R. Kashyap.
Surgery, University of Rochester Medical Center, Rochester, NY.
Purpose: Biliary complications following liver transplantation are a significant source of morbidity, potentially leading to graft failure necessitating retransplantation. Smoking precipitates both microvascular and macrovascular…
2015 American Transplant Congress
A Relative Survival Model to Compare the Risk of Mortality in Patients Awaiting Kidney Transplantation Versus Already Transplanted Patients
M. Lorent,^1,2 K. Trébern-Launay,^2,1 C. Legendre,⁴ H. Kreis,⁴ G. Mourad,⁵ V. Garrigue,⁵ L. Rostaing,⁶ N. Kamar,⁶ M. Kessler,⁷ M. Ladrière,⁷ E. Morelon,⁸ F. Buron,⁸ M. Giral,^2,3 Y. Foucher.^1,2
¹EA 4275 - SPHERE bioStatistics, Pharmacoepidemiology and Human Sciences Research, Nantes University, Nantes, France; ²Institut de Transplantation, Urologie, Néphrologie (ITUN), Inserm U1064, CHU de Nantes, Nantes, France; ³CIC Biotherapy, CHU Nantes, Nantes, France; ⁴Service de Transplantation Rénale et de Soins Intensifs, Hôpital Necker, APHP Paris, Paris, France; ⁵Service de Néphrologie-Transplantation, Hôpital Lapeyronie, Montpellier, France; ⁶Service de Néphrologie, HTA, Dialyse et Transplantation d'Organes, CHU Rangueil, Toulouse, France; ⁷Service de Transplantation Rénale, CHU Brabois, Nancy, France; ⁸Service de Néphrologie, Transplantation et Immunologie Clinique, Hôpital Edouard Herriot, Lyon, France.
Introduction: It would be useful for physicians in some specific cases to identify whom patients could not benefit of kidney transplantations.Patients and method: To answer…