2015 American Transplant Congress
Incidence and Risks Associated With Clostridium Difficile Infection in the Pediatric Solid Organ Transplantation Population: A Single-Center Retrospective Review
1Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 2Xavier University, Cincinnati, OH.
Morbidity and mortality related to Clostridium difficile Infection (CDI) has increased. Adult SOT data have reported risk factors for CDI. We interrogated the epidemiology of…2015 American Transplant Congress
Early Hospital Readmission and Distance from Transplant Center
Background: Early hospital readmission occurs in 31% of kidney transplant (KT) recipients and may be associated with mechanistic factors not previously captured in patient-level risk…2015 American Transplant Congress
Treatment With Everolimus and Reduced-Exposure Cyclosporine Is Efficacious in De Novo Renal Transplant Recipients at Increased Risk for Efficacy Failure: Post-Hoc Analysis from the A2309 Study
1For the A2309 Study Group, Italy; 2Novartis, Basel, Switzerland.
Purpose: Data is limited on the effect of everolimus (EVR) based regimens in renal transplant recipients (RTxR) who are at increased risk for rejection and…2015 American Transplant Congress
UNOS KDPI Score Is Significantly Overestimated for Pediatric En-Bloc Kidneys
Transplant Center, University of California, Davis, Sacramento, CA.
When Rao, et al, published the Kidney Donor Risk Index model (KDRI) (Transplantation 2009;88:231-236), they found coefficients for HLA match, cold ischemic time, en-bloc (EB)…2015 American Transplant Congress
Cumulative Incidence, Risk Factors for and Impact on Survival of Severe Chronic Kidney Disease After Intestinal Transplantation: Analysis of the SRTR Database
Background: Patient and graft survival rates after intestinal transplantation (ITx) have improved. More ITx recipients achieve long-term survival and are at risk for severe chronic…2015 American Transplant Congress
High Within-Patient Variability in Tacrolimus Levels Is a Predictor of Late Rejection in Young Adult Kidney Transplant Recipients
Introduction: Non-adherence is an important risk factor for late rejection (rejection > 3 months post-transplant) and is the main reason why 17-29 year old kidney…2015 American Transplant Congress
Implementation of Pre-Transplant Infectious Disease Risk Assessment: Sustained Success With Rapid-Cycle Improvement
Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Pre-transplant infectious disease risk assessment can identify and mitigate potential risk for transplant candidates to improve post-transplant outcomes. We aimed to improve pre-transplant ID risk…2015 American Transplant Congress
Factors Affecting Efficacy Outcomes at 12 and 24-Months After Kidney Transplantation in Patients from the A2309 Study
1Novartis, Basel, Switzerland; 2A2309 Study Group, Basel, Switzerland; 3Novartis, East Hanover, NJ.
Purpose: Efficacy outcomes post-transplantation are influenced by donor and recipient variables and interactions between them. Here, we present data from a multivariate analysis of risk…2015 American Transplant Congress
Examining Long-Term Survivors in Combined Heart-Lung Transplantation
The goal of this study was to determine variables associated with mortality in combined heart-lung transplantation (HLT).The United Network for Organ Sharing (UNOS) database was…2015 American Transplant Congress
Characteristics and Consequences of Renal Allograft Rejections Due to Nonadherence
Houston Methodist Hospital, Houston.
Non-adherence (NA) with immunosuppressive medications is associated with increased healthcare costs, rejection risk, and graft loss. NA is difficult to measure, however, and is often…
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