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Articles tagged "Risk factors"

  • 2015 American Transplant Congress

    Characteristics and Consequences of Renal Allograft Rejections Due to Nonadherence

    S. Patel, S. Kuten, J. Everett, J. Loucks-DeVos, L. Gaber, A. Gaber, R. Knight.

    Houston Methodist Hospital, Houston.

    Non-adherence (NA) with immunosuppressive medications is associated with increased healthcare costs, rejection risk, and graft loss. NA is difficult to measure, however, and is often…
  • 2015 American Transplant Congress

    Increased Late Graft Loss in Kidney Recipients With Serum Sickness Disease Following Anti-Thymocyte Globulin Induction: Relation With an Anti-Neu5Gc Response

    A. Salama,1,2 G. Couvrat-Desvergnes,1 M. Lorent,1,3 G. Evanno,1 L. Le Berre,1 P. Hruba,4 P. Vesely,5 P. Guerif,1 A. Nicot,1 J.-M. Bach,6 Y. Foucher,1,3 S. Brouard,1 S. Castagnet,7 O. Viklicky,4 M. Giral,1 J. Harb,1 S. Jean-Paul.1

    1INSERM UMR 1064, ITUN, CHU de Nantes, Nantes University, Nantes, France; 2Société d'Accélération du Transfert de Technologies Ouest Valorisation, Rennes, France; 3EA 4275 SPHERE, Biostatistics, Clinical Research and Pharmaco-Epidemiology, Nantes, France; 4Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 5Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic; 6IECM, EA4644 University/ONIRIS USC1383 INRA, ONIRIS, Nantes, France; 7EFS Pays de la Loire, Nantes, France.

    Anti-thymocyte globulins (ATG) are rabbit IgGs against human T cells widely used as induction treatment of kidney recipients. ATG can induce immune-complex diseases including Serum…
  • 2015 American Transplant Congress

    Risk Factors for Infections After Transplant in a Prospective Cohort Study Including Incompatible Kidney Transplant Recipients

    R. Avery,1 H.-L. Tsai,2 C.-Y. Huang,2 S. Shoham,1 D. Ostrander,1 N. Lu,1 R. Montgomery,3 K. Marr.1

    1Infectious Disease, Johns Hopkins, Baltimore, MD; 2Biostatistics and Bioinformatics, Johns Hopkins, Baltimore, MD; 3Transplant Surgery, Johns Hopkins, Baltimore, MD.

    Background: Infectious morbidity is a cumulative function of recurrent events. Historically, data collection has depended on time-to-event analyses, variable definitions, and retrospective data. To better…
  • 2015 American Transplant Congress

    Intrapatient Variability of Tacrolimus Blood Concentrations Following Renal Transplant – Acute Rejection or No Connection?

    D. Katarey,1,2 E. Ioannou,2 I. MacPhee.1,2

    1Renal Medicine, St George's Hospital, London, United Kingdom; 2St George's University of London, London, United Kingdom.

    Background: A high degree of intrapatient variability (IPV) of tacrolimus blood concentrations has been associated with poor long-term outcome (1). Periods of under-exposure with increased…
  • 2015 American Transplant Congress

    Determinants and Sequelae of Hepatic Artery Thrombosis After Liver Transplantation: A Registry Study of Recipient Diagnosis and Coagulopathy

    J. Garonzik Wang,1 M. Doyle,1 K. Collins,1 J. Lowell,1 Y. Lin,1 S. Shenoy,1 J. Wellen,1 W. Chapman,1 D. Segev.2

    1Washington University, Barnes Jewish Hospital, Saint Louis, MO; 2Johns Hopkins University, Johns Hopkins Hospital, Baltimore, MD.

    Hepatic artery thrombosis (HAT) is a dreaded complication following liver transplantation. Despite improvements in technique and procurement, HAT still occurs in approximately 2-5% of recipients.…
  • 2015 American Transplant Congress

    Incidence and Outcomes of Polyomavirus Infection in 639 Kidney Transplant Recipients: Are High Immunological Risk Characteristics More Relevant Than Specific Induction Or Maintenance Immunosuppressive Regimens?

    E. Favi,1 L. Harris,2 J. Worsfold,2 R. Cacciola,1 C. Puliatti,1 C. Sammartino,1 R. Sivaprakasam.1

    1Transplantation, Royal London Hospital, London, United Kingdom; 2Barts and The London School of Medicine and Dentistry, London, United Kingdom.

    Introduction. Polyomavirus-associated nephropathy (PVAN) is now recognized as an important cause of graft dysfunction and early kidney transplant loss. Over-immunosuppression is the main risk factor…
  • 2015 American Transplant Congress

    Acute Kidney Injury in Kidney Transplant Patients According to the KDIGO Criteria

    T. Filiponi, A. Silva-Filho, E. Tonato, L. Requiao-Moura, A. Matos, E. Arruda, R. Chinen, L. Pires, M. Durão Junior.

    Kidney Transplantation, Albert Einstein Hospital, Sao Paulo, Brazil.

    Purpose.To assess the incidence, risk factors and outcomes associated with acute kidney injury (AKI) in kidney transplant in patients using KDIGO classification. Methods- Retrospective cohort…
  • 2015 American Transplant Congress

    Return to Work and Occupational Infection Risks in Transplant Recipients

    R. Avery,1 D. Ostrander,1 S. Shoham,1 S. Alp,2 N. Lu,1 C. Cave,1 E. Kraus,3 K. Marr.1

    1Infectious Disease, Johns Hopkins, Baltimore, MD; 2Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey; 3Nephrology, Johns Hopkins, Baltimore, MD.

    Background: Counseling is commonly provided to transplant recipients who are planning to return to work, regarding potential infection risks in the workplace. However, the nature…
  • 2015 American Transplant Congress

    Risk Factors for Graft Loss in Pediatric Renal Transplant Recipients After Transfer of Care

    B. Coyne,1,2 P. Hollen,1,2 Y. Guofen,3 K. Brayman.4

    1Department of Pediatrics, University of Virginia Health System, Charlottesville, VA; 2School of Nursing, University of Virginia, Charlottesville, VA; 3Department of Public Health Sciences, University of Virginia Health System, Charlottesville, VA; 4Department of Surgery, University of Virginia Health System, Charlottesville, VA.

    Improvements in immunosuppression and transplant surgical technique have increased the survival of children with end-stage renal disease. These patients have complex needs, and the current…
  • 2015 American Transplant Congress

    Tobacco Use Is a Significant Risk Factor for Post-Transplant Biliary Complications

    D. Dulaney, M. Dokus, M. Orloff, R. Kashyap.

    Surgery, University of Rochester Medical Center, Rochester, NY.

    Purpose: Biliary complications following liver transplantation are a significant source of morbidity, potentially leading to graft failure necessitating retransplantation. Smoking precipitates both microvascular and macrovascular…
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