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Articles tagged "Risk factors"

  • 2016 American Transplant Congress

    Increased Incidence of Clostridium difficile Infections with Proton Pump Inhibitor Use Post-Kidney Transplant.

    M. Spinner,1 K. Patel,1 E. Neuner,1 B. Stephany.2

    1Department of Pharmacy, Cleveland Clinic, Cleveland, OH; 2Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH.

    Clostridium difficile infection (CDI) is often encountered in the solid-organ transplant patient population. The incidence in kidney transplant recipients ranges between 3.5-16%. There are CDI…
  • 2016 American Transplant Congress

    Characteristics and Outcomes of Vancomycin Resistant Enterococcus Bacteremia After Liver Transplant.

    R. Odrobina,1 C. Kovacs,1 R. Butler,2 C. Koval.1

    1Department of Infectious Diseases, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    Vancomycin Resistant Enterococcus (VRE) infection is reported in 5-20% of liver transplant (LT) recipients and is associated with decreased survival. Published data includes infections of…
  • 2016 American Transplant Congress

    Evaluation of Scoring Systems Predicting Patient Survival at Time of Kidney Transplantation.

    O. Staeck, D. Khadzhynov, A. Kleinsteuber, L. Lehner, M. Duerr, K. Budde, F. Halleck.

    Nephrology, Charite, Berlin, Germany.

    Introduction:Estimating life expectancy in kidney transplant recipients (KTR) at time of transplantation is important to achieve the best functional match between patient and graft survival.…
  • 2016 American Transplant Congress

    Virological Profile of Deceased Organ Donors in the UK.

    M. Lawrance,1 K. Davison,1 I. Ushiro-Lumb,2 S. Lattimore (deceased),1 S. Brailsford.1,2

    1NHSBT/PHE Epidemiology Unit, Public Health England, London, United Kingdom; 2NHS Blood & Transplant, London, United Kingdom.

    Background: To date there has been no routine surveillance of infections in deceased solid organ donors in the UK. A national scheme to monitor infectious…
  • 2016 American Transplant Congress

    Incidence of Post-Transplant Lymphoproliferative Disorder in First, Kidney-Only Transplant Recipients Remains Stable.

    J. Molony,1 Y. Peng,1 N. Baker,2 U. Meier-Kriesche,3 J. Snyder.1

    1Chronic Disease Research Group, Minneapolis; 2Brystol-Myers Squibb Company (BMS), Hopewell; 3BMS, Lawrenceville.

    We estimated the incidence of and risk factors for post-transplant (TX) lymphoproliferative disorder (PTLD) in the 3 years post-TX for adults with first, kidney-only TX…
  • 2016 American Transplant Congress

    Clinical Risk Factors for the Recurrence of Clostridium difficile Infection (CDI) in Solid Organ Transplant Recipients (SOTR).

    Y. Natori, M. Shiotsuka, L. Oen, E. Renner, L. Singer, J. Kim, H. Ross, D. Kumar, C. Rotstein, A. Humar, S. Husain.

    Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.

    Introduction:CDI is a common complication in SOTR. Recurrence may occur after treatment of the initial episode. However, the clinical risk factors of the recurrence of…
  • 2016 American Transplant Congress

    Three-Year Graft Loss Risk in Kidney Transplants: Dynamic Patient Level Data Improve Predictive Efficacy.

    T. Srinivas, J. Zhang, Z. Su, D. Taber, J. Marsden, K. Reilly, D. Northrup, J. Long, L. Lenert, W. Moran, P. Mauldin.

    MUSC, Charleston, SC.

    Background: Predictive models in kidney transplantation using national data (UNOS, SRTR) lack longitudinal patient level data, limiting accuracy. Adding patient level data capturing dynamic clinical…
  • 2016 American Transplant Congress

    Obesity Is Associated with Increased Risk of ESRD Among Living Kidney Donors.

    J. Locke,1 C. Lewis,1 R. Reed,1 V. Kumar,1 D. Sawinski,2 A. Massie,3 P. MacLennan,1 R. Mannon,1 R. Gaston,1 D. Segev.3

    1School of Medicine, University of Alabama at Birmingham, Birmingham, AL; 2School of Medicine, University of Pennsylvania, Philadelphia, PA; 3School of Medicine, Johns Hopkins University, Baltimore, MD.

    Background: Living kidney donor (LKD) demographics have changed, and transplant centers have relaxed selection criteria to include LKDs who are obese. Prior studies of LKDs…
  • 2016 American Transplant Congress

    VDJ Immune Repertoire Sequencing Predicts Patients at Risk of Alloimmune Injury.

    M. Sirota,1 T. Sigdel,1 S. Boyd,2 A. Fire,2 M. Sarwal.1

    1Surgery and Bioinformatics, UCSF, San Francisco, CA; 2Genetics, Stanford University, Palo Alto, CA.

    Background: The complex repertoire of immune receptors generated by B cells enables allo-recognition in the context of transplantation across HLA barriers, and is a major…
  • 2016 American Transplant Congress

    Review of Organ Utilization from Increased Infectious Risk Donors.

    A. L'Huillier,1 A. Humar,2 C. Payne,3 D. Kumar.2

    1Division of Infectious Diseases, Hospital for Sick Children and University of Toronto, Toronto, Canada; 2Transplant Infectious Diseases and Multi-Organ Transplant Program, University Health Network, Toronto, Canada; 3Trillium Gift of Life Network, Toronto, Canada.

    IntroductionDonors with an increased risk of transmitting HIV, HBV or HCV (IRDs) are a potential source of organs. There is a lack of data on…
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