Articles tagged "Renal function"

2019 American Transplant Congress
Recipients with Model for End-Stage Liver Disease Sodium Score Driven by Renal Dysfunction Have Increased Post-Transplant Mortality
T. Bittermann, D. Goldberg
Gastroenterology, University of Pennsylvania, Philadelphia, PA
*Purpose: Since the adoption of the Model for End-stage Liver Disease (MELD) score as a primary means of waitlist prioritization for liver transplantation (LT), an…
2019 American Transplant Congress
Microvascular Rarefaction and Long-Term Graft Dysfunction in Kidney Transplant Recipients with Delayed Graft Function
A. Doreille, S. Larivière-Beaudoin, A. Karakeussian-Rimbaud, M. Hébert, M. Dieudé, N. Patey, H. Cardinal
1Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada
*Purpose: Delayed graft function (DGF), or acute kidney injury in the perioperative period, is associated with decreased kidney graft survival.*Methods: As animal studies suggest that…
2019 American Transplant Congress
Effect of Renal Function on Asymmetric Dimethylarginine (ADMA) Homeostasis in Kidney Donors and Recipients
M. Y. Said¹, R. M. Douwes¹, M. van Londen¹, I. Minović¹, A. Frenay², M. H. de Borst¹, E. van den Berg¹, M. R. Heiner-Fokkema³, A. A. Kayacelebi⁴, A. Bollenbach⁴, H. van Goor⁵, G. J. Navis¹, D. Tsikas⁴, S. J. Bakker¹
¹Internal medicine, University Medical Center Groningen, Groningen, Netherlands, ²Gynecology and Obstetrics, Amsterdam University Medical Center, Amsterdam, Netherlands, ³Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands, ⁴Inst. of Toxicology, Core Unit Proteomics, Hannover Medical School, Hannover, Germany, ⁵Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands
*Purpose: ADMA is a methylated form of arginine and an endogenous nitric oxide synthase inhibitor. Plasma ADMA (pADMA) is known as a strong cardiovascular risk…
2019 American Transplant Congress
Hephaistos Study Outcome on Renal Function after 12 Month Everolimus Plus Reduced Tacrolimus in De Novo Liver Transplant Recipients versus Standard Tacrolimus
F. Braun¹, P. Schemmer¹, H. Schlitt¹, A. Pascher¹, C. Klein¹, U. Neumann¹, I. Kroeger², P. Wimmer², B. Nashan¹
¹Study Group, Hephaistos, Germany, ²Novartis Pharma GmbH, Nuernberg, Germany
*Purpose: The HEPHAISTOS study was designed to compare efficacy and safety of earlyuse of everolimus [EVR] combined with reduced tacrolimus [rTAC] versus Standard tacrolimus [TAC-C)…
2019 American Transplant Congress
Need of a New Formula to Estimate Creatinine Clearance in Immediate Post Kidney Transplant Period with Functioning Allograft
A. B. Jain¹, U. Farooq², A. Brooks¹, T. Dohi¹, F. Butt¹, Z. Kadry¹
¹Surgery ( Transplant), Penn State Milton Hershey Medical Center, Hershey 17033, PA, ²Medicine( Neprhology), Penn State Milton Hershey Medical Center, Hershey, PA
*Purpose: Introduction: Post kidney transplant (KTx), with functioning renal allograft, serum creatinine continues to decrease at a variable rate until it stabilizes after a few…
2019 American Transplant Congress
Consistent High Burden of Arteriosclerosis in Pediatric Kidney Transplant Recipients
K. Ostendorf¹, N. Memaran¹, B. Borchert-Mörlins¹, J. von der Born¹, E. Bauer¹, A. von Wick¹, J. Oh², M. J. Kemper³, R. Büscher⁴, B. M. Schmidt⁵, A. Melk¹
¹Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany, ²Pediatric Nephrology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, ³Department of Pediatrics, Asklepios Klinik Nord - Heidberg, Hamburg, Germany, ⁴Pediatric Nephrology, University Hospital, Essen, Germany, ⁵Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany
*Purpose: The second most common cause of death in pediatric kidney transplant (KT) recipients are cardiovascular (CV) diseases. We have previously shown that pulse wave…
2019 American Transplant Congress
Normothermic Ex-Vivo Kidney Perfusion Preservation Consistently Improves Extreme Marginal Graft Function Compared to Hypothermic Machine Perfusion
P. Urbanellis¹, M. Hamar¹, I. Linares¹, D. Kollmann¹, S. Ganesh¹, F. Oquendo¹, M. Sharma¹, R. John¹, A. Ghanekar¹, I. Mucsi¹, D. Bagli², A. Konvalinka¹, L. Robinson³, M. Selzner¹
¹Multi-Organ Transplantation Program, University Health Network, Toronto, ON, Canada, ²Division of Urology, The Hospital for Sick Children, Toronto, ON, Canada, ³Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: Normothermic ex-vivo kidney perfusion (NEVKP) is an emerging technique for renal graft preservation. We investigated whether NEVKP promoted improved marginal graft function compared to…
2019 American Transplant Congress
First UK Experience of the Molecular Microscope (MMDX™) in the Kidney Transplant Clinic
C. Lawrence¹, S. Thiru², A. Manoj¹, S. Fluck¹
¹Renal Medicine, The Lister Hospital, Stevenage, United Kingdom, ²Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom
*Purpose: Molecular diagnostic methods are now included in the Banff classification of kidney transplant pathology. Traditional histopathology may be limited by intra/inter pathologist variation. The…
2019 American Transplant Congress
Endovascular Repair Of Abdominal Aortic Aneurysms In Kidney Transplant Recipients
S. Kwon¹, D. Jung¹, Y. Kim¹, S. Park², S. Yoon²
¹Department of Vascular and Transplant Surgery, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ²Department of Vascular and Transplant Surgery, The Catholic Universtiy of Korea, Seoul St. Mary's Hospital, Seoul, Korea, Republic of
*Purpose: The possibility to diagnosis abdominal aortic aneurysm (AAA) in patients who underwent kidney transplantation (KT) is increasing. Immunosuppressive agents may effect on AAA progression.…
2019 American Transplant Congress
Long Term Renal Function Following Islet Transplantation in the Clinical Islet Transplantation Consortium
L. G. Hunsicker¹, T. L. Eggerman², M. R. Rickels³, t. Clinical Islet Transplantation (CIT) Consortium⁴
¹Internal Medicine, U. Iowa, Iowa City, IA, ²NIDDK/NIH, Bethesda, MD, ³Internal Medicine, U. Pennsylvania, Philadelphia, PA, ⁴Internal Medicine, University of Iowa, Iowa City, IA
*Purpose: Islet transplantation (IsletTp) is safe and effective treatment of Type 1 diabetes complicated by severe hypoglycemia (Diabetes Care 2016, 39:1230). But the requirement for…

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