Articles tagged "Renal function"

2020 American Transplant Congress
Long Term Effect of Tacrolimus Conversion to Sirolimus with Prednisone-Free Regimen in Kidney Allograft Outcomes: A Dynamic Analysis of Graft Survival Using Joint Modeling
S. H. Park¹, B. Ho¹, K. Guo¹, L. Zhao², V. Mas³, J. Leventhal⁴, L. Gallon¹
¹Transplant Nephrology, Northwestern University, Chicago, IL, ²Preventive Medicine, Northwestern University, Chicago, IL, ³University of Tennesse, Memphis, TN, ⁴Transplant Surgery, Northwestern University, Chicago, IL
*Purpose: Findings on long-term impacts of the mammalian target of rapamycin inhibitor inhibitors on kidney allograft are scarce and mixed. A joint modeling approach can…
2020 American Transplant Congress
Donor-Derived Cell-Free DNA Combined with Histology Improves Prediction of eGFR Decline in Kidney Transplant Recipients over Histology Alone
M. Gillespie, M. Haas, K. Lim, A. Vo, A. Peng, R. Najjar, S. Sethi, S. Jordan, E. Huang
Cedars-Sinai, Los Angeles, CA
*Purpose: Higher Banff inflammation and chronicity scores on kidney transplant (KTx) biopsies (Bx) have been associated with poorer graft survival, but Bx scores alone imperfectly…
2020 American Transplant Congress
Minor Negative Effects of Calcineurin Inhibitor Based Immunosuppression on Pregnancy Outcomes after Renal Transplantation in the Netherlands
L. M. Koenjer¹, J. R. Meinderts², A. T. Lely³, M. F. de Jong², O. W. van der Heijden¹, R. G. van der Molen⁴, H. W. van Hamersvelt⁵
¹Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, Netherlands, ²Nephrology, University Medical Center Groningen, Groningen, Netherlands, ³Obstetrics and Gynaecology, University Medical Center Utrecht, Utrecht, Netherlands, ⁴Immunology, Radboud University Medical Centre, Nijmegen, Netherlands, ⁵Nephrology, Radboud University Medical Centre, Nijmegen, Netherlands
*Purpose: Pregnancies after renal transplantation became more frequent over the past years, also in patients with compromised renal function. Immunosuppression may influence pregnancy outcome. It…
2020 American Transplant Congress
Urinary CXCL10: From Diagnosis to Prediction of BK Viremia in Kidney Transplantation
C. Tinel¹, A. Vermorel¹, D. Picciotto¹, L. Morin¹, C. Legendre¹, M. Rabant², D. Anglicheau¹
¹Kidney Transplantation, Inserm U1151, Necker Hospital, Paris, France, ²Pathology, Necker Hospital, Paris, France
*Purpose: Urinary CXCL10 (uCXCL10) has proved to be a useful tool for the non-invasive diagnosis of acute rejection in kidney transplant recipients (KTRs). Upon development,…
2020 American Transplant Congress
Envarsus XR Use Can Benefit Serum Creatinine Levels in Vascularized Composite Allotransplantation Patients
C. M. Cooney¹, V. Javia¹, J. Littleton¹, D. S. Cooney¹, R. J. Redett¹, J. T. Shores¹, D. C. Brennan², G. Brandacher¹
¹Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, ²Surgery, Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Vascularized composite allotransplantation (VCA) is a life-enhancing (as opposed to life-saving) procedure. Therefore, minimizing adverse outcomes associated with chronic immunosuppression is vital to determining…
2020 American Transplant Congress
Determinants of Cardiovascular Benefit Observed in a Population with a Functioning Renal Transplant versus Patients Undergoing Chronic Dialysis
J. Sleiman, C. Castellaro, G. Laham, M. Schiavone, M. Biain, L. Brukman, G. Soler Pujol, C. Diaz
Nephrology, CEMIC, Caba, Argentina
*Purpose: Patients (pts) with end stage renal disease have a high morbidity and mortality rate, mostly due to cardiovascular events (CV). Transplantation (Tx) improves survival…
2020 American Transplant Congress
Pancreas Transplant in Chronic Kidney Disease for Type 1 Diabetic Patients
R. A. Choudhury, D. Yoeli, H. B. Moore, H. Yaffe, K. D. Conzen, T. L. Nydam, P. T. Kennealey
Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO
*Purpose: Although both pancreas transplantation alone (PTA) and islet cell transplantation (ICT) have been associated with peri-operative declines in eGFR, the magnitude of decline is…
2020 American Transplant Congress
Outcomes of De Novo Belatacept-Based Immunosuppression in Recipients of Kidneys at High Risk for Delayed Graft Function in the Setting of Lymphocyte Depleting Immune Modulation
T. L. Shertel¹, M. A. Wynd¹, M. A. Pereiras¹, J. T. McKeen¹, Y. Y. Yushkov², B. R. Schleich³, S. E. Geatrakas², A. Patel², M. J. Goldstein²
¹Pharmacy, Hackensack University Medical Center, Hackensack, NJ, ²Organ Transplant, Hackensack University Medical Center, Hackensack, NJ, ³Patient Safety and Quality, Hackensack University Medical Center, Hackensack, NJ
*Purpose: Our center created an immunosuppression protocol using de novo belatacept (DNB) in the setting of lymphocyte depletion to increase the utilization of deceased donor…
2020 American Transplant Congress
Does Donor Terminal, Admission or Best Estimate Glomerular Filtration Rate Predicts Kidney Transplantation Outcomes
G. Irish¹, T. Coates², P. Clayton²
¹Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, South Australian Health and Medical Research Institute, Adelaide, Australia, ²Central and Northern Adelaide Renal and Transplantation Services, Royal Adelaide Hospital, Adelaide, Australia
*Purpose: When assessing deceased kidney donors, a key factor is donor kidney function. It is unclear whether terminal, admission, or the best of terminal and…
2020 American Transplant Congress
Trajectories of Glomerular Filtration Rate and Progression to End Stage Renal Disease after Kidney Transplantation
M. Raynaud¹, O. Aubert¹, P. Reese², M. Naesens³, D. Glotz¹, C. Legendre¹, S. Jordan⁴, M. Stegall⁵, D. Segev⁶, C. Lefaucheur¹, A. Loupy, On behalf of the study NCT03474003¹
¹Paris Transplant Group, Paris, France, ²University of Pennsylvania, Philadelphia, PA, ³Department of Transplantation, Leuven, Belgium, ⁴Cedars Sinai, Los Angeles, CA, ⁵Mayo Clinic, Rochester, MN, ⁶Johns Hopkins, Baltimore, MD
*Purpose: Although the current gold standard of monitoring kidney transplant function relies on glomerular filtration rate (GFR) assessment, little is known about GFR trajectories after…

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