Articles tagged "Renal function"

2018 American Transplant Congress
Kidney Transplantation from Uncontrolled Donation after Circulatory Death, Good Outcomes after Very Long Time
M. Molina,¹ J. Cabrera,² E. Gonzalez,¹ A. Hernandez,¹ P. Natalia,¹ A. Andres.¹
¹Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain; ²Department of Nephrology, Hospital Evangelico, Montevideo, Uruguay.
Introduction: Kidney transplantation (KT) is the best renal replacement therapy but the shortage of organ is the main limitation. Uncontrolled Donation after Circulatory Death (uDCD)…
2018 American Transplant Congress
Everolimus with Reduced-Dose Calcineurin Inhibitor versus Mycophenolate with Standard-Dose Calcineurin Inhibitor in De Novo Kidney Transplant Recipients: Renal Function Results from the TRANSFORM Study
F. Oppenheimer,¹ C. Legendre,¹ J. Cruzado,¹ G. Russ,¹ O. Viklicky,¹ R. Oberbauer,¹ V. Garcia,¹ O. Witzke,¹ D. Kuypers,¹ R. Danguilan,¹ P. Bernhardt,² C. Sommerer.¹
¹TRANSFORM Study Group, Barcelona, Spain; ²Novartis Pharma AG, Basel, Switzerland.
Purpose: TRANSFORM (NCT01950819) is the largest study conducted in de novo kidney transplant recipients (KTxRs) to evaluate the benefit of everolimus with reduced-dose calcineurin inhibitor…
2018 American Transplant Congress
Development of a Screening Tool to Predict Chronic Kidney Disease Risk in Post-Nephrectomy Living Kidney Donors
J. Na,¹ J. Park,¹ M-.G. Yoon,¹ H. Lee,² Y. Yoon,³ K. Huh,⁴ M. Kim,⁴ S. Kim,⁴ Y. Kim,⁴ W. Han.¹
¹Department of Urology, Yonsei University College of Medicine, Urological Science Institute, Seoul, Korea; ²Department of Urology, National Health Insurance Service Ilsan Hospital, Goyang-si, Korea; ³Department of Urology, Hanyang University Medical Center, Seoul, Korea; ⁴Department of Surgery-Transplantation, Yonsei University College of Medicine, Seoul, Korea.
Purpose: We aimed to develop a prediction models of chronic kidney disease (CKD) for the 1-year period after donor nephrectomy in living donors.Materials and Methods:…
2018 American Transplant Congress
Technical Challenges in Living Donor Kidney Transplantation – Diagnosis and Solutions
R. Öllinger,¹ K. Alqasim,¹ F. Klein,¹ N. Raschzok,¹ P. Ritschl,¹ S. Chopra,¹ N. Otto,² T. Denecke,³ U. Gerlach,¹ M. Schmelzle,¹ P. Reinke,² J. Pratschke.¹
¹Department of Surgery, Charité, Berlin, Germany; ²Department of Nephrology, Charité, Berlin, Germany; ³Department of Radiology, Charité, Berlin, Germany.
IntroductionDue to organ scarcity living donation is becoming a major source of kidneys for transplantation. Besides medical contraindications, anatomy of the kidneys may be a…
2018 American Transplant Congress
Allograft Function after 12 Months with Everolimus Plus Either Tacrolimus or Cyclosporine Compared to a Standard Regimen of Tacrolimus with MPA in De Novo Renal Transplant Recipients: The ATHENA Study
B. Nashan,¹ C. Sommerer,¹ B. Suwelack,¹ D. Dragun,¹ O. Witzke,¹ C. Hugo,¹ N. Kamar,² P. Merville,² A. Hauser,¹ P. Schenker,¹ M. Junge,³ F. Thaiss.¹
¹Athena Study Group, Germany; ²Athena Study Group, France; ³Novartis, Pharma, Germany.
The ATHENA study was designed to compare efficacy, safety and outcomes on renal function [GFR] of everolimus [EVR] combined with tacrolimus [TAC] or cyclosporine A…
2018 American Transplant Congress
Long-Term Renal Function in Living Kidney Donors with Renal Cysts
M. Waldram, A. Thomas, A. Muzaale, C. Holscher, A. Nguyen, S. Halpern, S. Anjum, J. Alejo, B. Boyarsky, S. Ottman, J. Garonzik-Wang, D. Segev, A. Massie.
JHU, Baltimore.
Renal cysts found during the evaluation of living kidney donor (LKD) candidates are often regarded as benign. However, it is possible that these structural abnormalities…
2018 American Transplant Congress
Liver Transplantation with or without Left Renal Vein Ligation: Comparative Study of 105 Cases
M. Perosa,¹ H. Noujaim,¹ J. Branez,¹ L. Mota,¹ B. Zeballos,¹ R. Santos,¹ A. Watanabe,² G. Ferreira,² A. Moraes,² A. Silvestre,³ G. Martinho,⁴ N. Siqueira,⁵ T. Genzini.¹
¹Abdominal Organ Transplantation, Leforte Hospital, Sao Paulo, Brazil; ²ICDF Hospital, Brasilia, Brazil; ³Medical School, Sao Camilo, Sao Paulo, Brazil; ⁴Medical School, Santa Casa, Sao Paulo, Brazil; ⁵Hospital das Clínicas, Rio Branco, Acre, Brazil.
The presence of large spontaneous splenorenal shunts (SSRS) is a risk factor for low portal flow and graft dysfunction after liver transplantation (LT). Left renal…
2018 American Transplant Congress
Ischemia Reperfusion Injury in Liver Transplantation is Associated with Acute Kidney Injury: Role of Inflammatory Mediators
P. Mihaylov,^1,2 P. Li,¹ J. Skill,¹ L. Timsina,¹ J. Fridell,¹ B. Ekser,¹ R. Mangus,¹ C. Kubal.¹
¹Surgery, Indiana University, Indianapolis; ²Surgery, University of Pavia, Pavia, Italy.
Background: The impact of liver allograft ischemia/reperfusion injury (IRI) on native renal function remains to be characterized. We hypothesized that elevated levels of circulating inflammatory…
2018 American Transplant Congress
Delayed Recovery of Renal Function after Donor Nephrectomy
J. Na,¹ J. Park,¹ M-.G. Yoon,¹ H. Lee,² Y. Yoon,³ K. Huh,⁴ M. Kim,⁴ S. Kim,⁴ Y. Kim,⁴ W. Han.¹
¹Department of Urology, Yonsei University College of Medicine, Urological Science Institute, Seoul, Korea; ²Department of Urology, National Health Insurance Service Ilsan Hospital, Goyang-si, Korea; ³Department of Urology, Hanyang University Medical Center, Seoul, Korea; ⁴Department of Surgery-Transplantation, Yonsei University College of Medicine, Seoul, Korea.
Introduction:Among living kidney donors at risk of CKD at 1 year after nephrectomy, some donors remain with poor renal function while many show delayed recovery…
2018 American Transplant Congress
Outcomes in Liver Transplant Patients on Renal Sparing Protocol
A. Polyak,¹ D. Ganger,² A. Shetty.²
¹New York Medical College, Valhalla, NY; ²Comprehensive Transplant Center, Northwestern University, Chicago, IL.
As liver transplant outcomes have improved, long term native kidney function has taken a critical role in patient survival. Calcineurin inhibitors (CNIs), such as Tacrolimus…