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American Transplant Congress abstracts

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Articles tagged "Renal function"

  • 2019 American Transplant Congress

    Microvascular Rarefaction and Long-Term Graft Dysfunction in Kidney Transplant Recipients with Delayed Graft Function

    A. Doreille, S. Larivière-Beaudoin, A. Karakeussian-Rimbaud, M. Hébert, M. Dieudé, N. Patey, H. Cardinal

    1Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada

    *Purpose: Delayed graft function (DGF), or acute kidney injury in the perioperative period, is associated with decreased kidney graft survival.*Methods: As animal studies suggest that…
  • 2019 American Transplant Congress

    Effect of Renal Function on Asymmetric Dimethylarginine (ADMA) Homeostasis in Kidney Donors and Recipients

    M. Y. Said1, R. M. Douwes1, M. van Londen1, I. Minović1, A. Frenay2, M. H. de Borst1, E. van den Berg1, M. R. Heiner-Fokkema3, A. A. Kayacelebi4, A. Bollenbach4, H. van Goor5, G. J. Navis1, D. Tsikas4, S. J. Bakker1

    1Internal medicine, University Medical Center Groningen, Groningen, Netherlands, 2Gynecology and Obstetrics, Amsterdam University Medical Center, Amsterdam, Netherlands, 3Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands, 4Inst. of Toxicology, Core Unit Proteomics, Hannover Medical School, Hannover, Germany, 5Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands

    *Purpose: ADMA is a methylated form of arginine and an endogenous nitric oxide synthase inhibitor. Plasma ADMA (pADMA) is known as a strong cardiovascular risk…
  • 2018 American Transplant Congress

    Everolimus with Reduced-Dose Calcineurin Inhibitor versus Mycophenolate with Standard-Dose Calcineurin Inhibitor in De Novo Kidney Transplant Recipients: Renal Function Results from the TRANSFORM Study

    F. Oppenheimer,1 C. Legendre,1 J. Cruzado,1 G. Russ,1 O. Viklicky,1 R. Oberbauer,1 V. Garcia,1 O. Witzke,1 D. Kuypers,1 R. Danguilan,1 P. Bernhardt,2 C. Sommerer.1

    1TRANSFORM Study Group, Barcelona, Spain; 2Novartis Pharma AG, Basel, Switzerland.

    Purpose: TRANSFORM (NCT01950819) is the largest study conducted in de novo kidney transplant recipients (KTxRs) to evaluate the benefit of everolimus with reduced-dose calcineurin inhibitor…
  • 2018 American Transplant Congress

    Development of a Screening Tool to Predict Chronic Kidney Disease Risk in Post-Nephrectomy Living Kidney Donors

    J. Na,1 J. Park,1 M-.G. Yoon,1 H. Lee,2 Y. Yoon,3 K. Huh,4 M. Kim,4 S. Kim,4 Y. Kim,4 W. Han.1

    1Department of Urology, Yonsei University College of Medicine, Urological Science Institute, Seoul, Korea; 2Department of Urology, National Health Insurance Service Ilsan Hospital, Goyang-si, Korea; 3Department of Urology, Hanyang University Medical Center, Seoul, Korea; 4Department of Surgery-Transplantation, Yonsei University College of Medicine, Seoul, Korea.

    Purpose: We aimed to develop a prediction models of chronic kidney disease (CKD) for the 1-year period after donor nephrectomy in living donors.Materials and Methods:…
  • 2018 American Transplant Congress

    Technical Challenges in Living Donor Kidney Transplantation – Diagnosis and Solutions

    R. Öllinger,1 K. Alqasim,1 F. Klein,1 N. Raschzok,1 P. Ritschl,1 S. Chopra,1 N. Otto,2 T. Denecke,3 U. Gerlach,1 M. Schmelzle,1 P. Reinke,2 J. Pratschke.1

    1Department of Surgery, Charité, Berlin, Germany; 2Department of Nephrology, Charité, Berlin, Germany; 3Department of Radiology, Charité, Berlin, Germany.

    IntroductionDue to organ scarcity living donation is becoming a major source of kidneys for transplantation. Besides medical contraindications, anatomy of the kidneys may be a…
  • 2018 American Transplant Congress

    Allograft Function after 12 Months with Everolimus Plus Either Tacrolimus or Cyclosporine Compared to a Standard Regimen of Tacrolimus with MPA in De Novo Renal Transplant Recipients: The ATHENA Study

    B. Nashan,1 C. Sommerer,1 B. Suwelack,1 D. Dragun,1 O. Witzke,1 C. Hugo,1 N. Kamar,2 P. Merville,2 A. Hauser,1 P. Schenker,1 M. Junge,3 F. Thaiss.1

    1Athena Study Group, Germany; 2Athena Study Group, France; 3Novartis, Pharma, Germany.

    The ATHENA study was designed to compare efficacy, safety and outcomes on renal function [GFR] of everolimus [EVR] combined with tacrolimus [TAC] or cyclosporine A…
  • 2018 American Transplant Congress

    Long-Term Renal Function in Living Kidney Donors with Renal Cysts

    M. Waldram, A. Thomas, A. Muzaale, C. Holscher, A. Nguyen, S. Halpern, S. Anjum, J. Alejo, B. Boyarsky, S. Ottman, J. Garonzik-Wang, D. Segev, A. Massie.

    JHU, Baltimore.

    Renal cysts found during the evaluation of living kidney donor (LKD) candidates are often regarded as benign. However, it is possible that these structural abnormalities…
  • 2018 American Transplant Congress

    Liver Transplantation with or without Left Renal Vein Ligation: Comparative Study of 105 Cases

    M. Perosa,1 H. Noujaim,1 J. Branez,1 L. Mota,1 B. Zeballos,1 R. Santos,1 A. Watanabe,2 G. Ferreira,2 A. Moraes,2 A. Silvestre,3 G. Martinho,4 N. Siqueira,5 T. Genzini.1

    1Abdominal Organ Transplantation, Leforte Hospital, Sao Paulo, Brazil; 2ICDF Hospital, Brasilia, Brazil; 3Medical School, Sao Camilo, Sao Paulo, Brazil; 4Medical School, Santa Casa, Sao Paulo, Brazil; 5Hospital das Clínicas, Rio Branco, Acre, Brazil.

    The presence of large spontaneous splenorenal shunts (SSRS) is a risk factor for low portal flow and graft dysfunction after liver transplantation (LT). Left renal…
  • 2018 American Transplant Congress

    Ischemia Reperfusion Injury in Liver Transplantation is Associated with Acute Kidney Injury: Role of Inflammatory Mediators

    P. Mihaylov,1,2 P. Li,1 J. Skill,1 L. Timsina,1 J. Fridell,1 B. Ekser,1 R. Mangus,1 C. Kubal.1

    1Surgery, Indiana University, Indianapolis; 2Surgery, University of Pavia, Pavia, Italy.

    Background: The impact of liver allograft ischemia/reperfusion injury (IRI) on native renal function remains to be characterized. We hypothesized that elevated levels of circulating inflammatory…
  • 2018 American Transplant Congress

    Delayed Recovery of Renal Function after Donor Nephrectomy

    J. Na,1 J. Park,1 M-.G. Yoon,1 H. Lee,2 Y. Yoon,3 K. Huh,4 M. Kim,4 S. Kim,4 Y. Kim,4 W. Han.1

    1Department of Urology, Yonsei University College of Medicine, Urological Science Institute, Seoul, Korea; 2Department of Urology, National Health Insurance Service Ilsan Hospital, Goyang-si, Korea; 3Department of Urology, Hanyang University Medical Center, Seoul, Korea; 4Department of Surgery-Transplantation, Yonsei University College of Medicine, Seoul, Korea.

    Introduction:Among living kidney donors at risk of CKD at 1 year after nephrectomy, some donors remain with poor renal function while many show delayed recovery…
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