Articles tagged "Renal function"

2019 American Transplant Congress
Belatacept Based CNI Free Immunosuppression in Pancreas Transplantation. Results at 4 Years
J. Chen, J. Fridell, M. Yaqub, T. Taber, D. MIshler, O. Adebiyi, M. Mujtaba, A. Sharfuddin
Indiana University School of Medicine, Indianapolis, IN
*Purpose: CNI based Immunosuppression is a well known risk factor for worsening renal function. We report our experience in converting Pancreas Transplant recipients from tacrolimus…
2019 American Transplant Congress
Monitoring Inflammatory Cytokine Levels in Kidney Transplant Patients (KTx Pts) with Chronic Antibody Mediated Rejection (cABMR) Treated with Clazakizumab (CLZ, Humanized Anti-IL-6 Monoclonal Antibody)
S. Ge¹, A. Petrosyan¹, M. Chu¹, N. Ammerman², A. Vo², S. C. Jordan², X. Zhang³, M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, ³HLA Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: IL-6 is a pro-inflammatory cytokine involved in KTx rejection. A clinical trial to improve cABMR using CLZ in HLA-sensitized KTx Pts is underway. Inhibition…
2019 American Transplant Congress
The Outcomes of Living Donor Kidney Transplantation in Donors or Recipients with Donors’ Renal Arteriosclerotic Lesions on Preoperative Computed Tomography
Y. Miyauchi, T. Noda, N. Miura, T. Kikugawa, T. Saika
Ehime University, Toon, Japan
*Purpose: Living donor kidney transplantation is being increasingly performed with elderly donors. Such elderly donors often have arteriosclerotic lesions (AS) (Figure 1). Whether the outcomes…
2019 American Transplant Congress
The Use of dd-cfDNA as a Predictive Tool for Outcome Decreased Kidney Function
T. Alhamad¹, E. Poggio², D. Hiller³, S. Dholakia³, P. Sood⁴
¹Washington University School of Medicine, St. Louis, MO, ²Cleveland Clinic, Cleveland, OH, ³CareDx, Brisbane, CA, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: A decline in estimated glomerular filtration rate (eGFR) during the first 12 months following kidney transplantation is associated with poor outcome and increased graft…
2019 American Transplant Congress
Change in Estimated Glomerular Filtration Rate and Risk of Allograft Failure in Patients Diagnosed with Active Antibody-Mediated Rejection Following Kidney Transplantation
W. Irish¹, P. Nickerson², B. Astor³, E. Chong⁴, C. Wiebe², F. Moreso⁵, D. Seron⁵, M. Crespo⁵, L. Gache⁶, A. Djamali³
¹East Carolina University, Greenville, NC, ²University of Manitoba, Winnipeg, MB, Canada, ³University of Wisconsin, Madison, WI, ⁴Vitaeris, Inc, Vancouver, BC, Canada, ⁵University Hospital Vall d'Hebron, Barcelona, Spain, ⁶CTI Clinical Trial & Consulting, Covington, KY
*Purpose: There are challenges in designing an adequate and well-controlled study of patients with active antibody-mediated rejection (ABMR), especially in the absence of a valid…
2019 American Transplant Congress
Use of Opioids and NSAIDs in Living Kidney Donors: Clinical Correlates and Early Outcomes
K. Lentine¹, L. Vest¹, Z. Zhang¹, F. Koraishy¹, M. Schnitzler¹, A. Garg², D. Axelrod³, B. Kasiske⁴, G. Hess⁵, A. Naik⁶, D. Segev⁷, M. Henderson⁷, A. Massie⁷, N. Lamm⁸
¹Saint Louis Univ, St. Louis, MO, ²Western Univ, London, ON, Canada, ³Univ of Iowa, Iowa City, IA, ⁴SRTR, Minneapolis, MN, ⁵Univ of Pennsylvania, Philadelphia, PA, ⁶Univ of Michigan, Ann Arbor, MI, ⁷Johns Hopkins, Baltimore, MD, ⁸Univ Alberta, Edmonton, AB, Canada
*Purpose: Data are limited regarding pain medication use in living kidney donors (LKD). Concerns relate to opioid use, and to non-steroidal anti-inflammatory (NSAID) use in…
2019 American Transplant Congress
Proximal Splenic Artery Embolization For Refractory Ascites And Hydrothorax After Liver Transplant: A Single Center Analysis Of Factors Associated With Success
L. Lomaglio, G. D'Amico, S. Armanyous, T. Diago Uso, K. Hashimoto, B. Eghtesad, M. Fujiki, F. Aucejo, K. Sasaki, C. Kwon, C. Coppa, M. Bayona Molano, C. Lindenmeyer, C. Miller, C. Quintini
Cleveland Clinic, Cleveland, OH
*Purpose: The aims of this study were to (1) assess the efficacy of proximal SAE for the treatment of RA and RH caused by portal…
2019 American Transplant Congress
Effect of Human Leukocytic Antigen Matching on Clinical Outcomes after Deceased Donor Renal Allograft Transplant: A Single Centre Experience
M. E. Gramlick¹, M. K. Heer², S. Yausis², P. R. Trevillian²
¹Department of Surgery, John Hunter Hospital, Newcastle, Australia, ²Newcastle Transplant Unit, John Hunter Hospital, Newcastle, Australia
*Purpose: Human leucocyte antigen (HLA) matching has been the cornerstone of kidney allocation policies. With increasing expertise in assessing and managing immunological risks, the impact…
2019 American Transplant Congress
Kidney Function Evaluation Among Living Donors In A Multiracial Population. The Results From A Brazilian Single-center Cohort Study.
L. R. Requião-Moura, P. R. Bicalho, A. Pacheco-Silva
Hospital Israelita Albert Einstein, São Paulo, Brazil
*Purpose: to assess renal function among living kidney donors in Brazil, where the population is greatly race-mixed.*Methods: This is a retrospective single-center cohort study involving…
2019 American Transplant Congress
Vaccine Response as a Predictor of Kidney Transplant Rejection and Serious Infection
A. Ta'eed, K. R. Polkinghorne, W. R. Mulley
Department of Nephrology, Monash Health, Clayton, Australia
*Purpose: Vaccination generates immune memory, including antibodies against harmful pathogens. Transplant immunosuppression prevents similar processes occurring against alloantigens. Transplant recipients have significantly reduced seroresponses to…