Articles tagged "Renal function"

2019 American Transplant Congress
The Influential Yet Highly Variable Role of Biopsy Findings on Kidney Offer Acceptance Decisions: An Organ Offer Simulation Study
D. Stewart¹, J. Rosendale¹, H. McGehee¹, I. Hall², G. Gupta³, K. Reddy⁴, B. Kasiske⁵, K. Andreoni⁶, D. Klassen¹
¹UNOS, Richmond, VA, ²Univ of Utah, Salt Lake City, UT, ³VCU, Richmond, VA, ⁴Mayo, Phoenix, AZ, ⁵HCMC, Minneapolis, MN, ⁶Univ of Florida, Gainesville, FL
*Purpose: The use of procurement biopsies (Bx) to assess kidney quality is controversial. ‘Biopsy findings’ is an often cited discard reason, yet the association between…
2019 American Transplant Congress
Effect of Everolimus with Reduced-Exposure Tacrolimus and Early Steroid Elimination in Pediatric Kidney Transplant Recipients: 36-Month Outcomes from the CRADLE Study
H. Tedesco Silva¹, R. Ettenger¹, A. Bjerre¹, M. Christian¹, L. Dello Strologo¹, S. D. Marks¹, L. Pape¹, P. Lopez², M. Cousin², P. Pandey², B. Rauer², M. Meier², B. Tönshoff¹
¹A2314 Study Group, Basel, Switzerland, ²Novartis Pharma AG, Basel, Switzerland
*Purpose: To compare 36-month (M) efficacy and safety outcomes of an everolimus+reduced-exposure tacrolimus (EVR+rTAC)+steroids (CS) withdrawal regimen vs mycophenolate mofetil+standard-exposure TAC (MMF+sTAC)+CS in pediatric kidney…
2019 American Transplant Congress
Evaluation of Delayed Renal Allograft Function after DCD with New Biomarkers in Donor Blood
X. Zheng
Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
*Purpose: To explore the relationship between new biomarkers in donor blood and delayed graft function (DGF) after DCD kidney transplantation, and to evaluate the clinical…
2019 American Transplant Congress
Preoperative Marginal Factors Do Not Affect the Medically Complex Living Donors for Kidney Transplantation
T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, M. Tsujita, T. Ichimori, N. Goto, S. Narumi, Y. Watarai
Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan
*Purpose: Recently, medically complex living donors with marginal factors including hypertension, dyslipidemia, glucose intolerance, and obesity are increasing. The impact of preoperative marginal factors on…
2019 American Transplant Congress
Utilization of Hepatitis C Donors is Safe and Cost Effective
J. Shaw, D. Reino, N. Kapila, K. Al Khalloufi, S. Ebaid, S. Rhazouani, X. Zervos, J. Vanatta, N. Agrawal
Cleveland Clinic, Weston, FL
*Purpose: The use of hepatitis C (hep C) positive donors has become increasingly attractive with the advent of improved curative pharmacologic treatments. As a result…
2019 American Transplant Congress
Long-Term Survival after Kidney-Pancreas Transplantation: Lessons from World Largest Series of Long-Term Survivors
S. Parajuli, F. Aziz, N. Garg, B. Muth, A. Djamali, R. Redfield, D. Kaufman, J. Odorico, D. Mandelbrot, H. Sollinger
University of Wisconsin, Madison, WI
*Purpose: Since 1983, more than 1700 patients have undergone pancreas transplant, mainly as a simultaneous-kidney-pancreas transplant (SPK) at our center. Forty-eight SPK recipients have pancreas…
2019 American Transplant Congress
Non-Invasive Monitoring of the Kidney Allograft
S. Bontha¹, G. Darville¹, C. Kuscu¹, C. Kuscu², A. Bajwa¹, J. Eason³, D. Maluf⁴, V. Mas⁵
¹Surgery, UTHSC, Memphis, TN, ²Surgery, UTHSC, memphis, TN, ³Surgery, Director of Transplant Institute - UTHSC, Memphis, TN, ⁴UTHSC, Memphis, TN, ⁵Surgery, Director of Transplant Research Institute, Memphis, TN
*Purpose: A major issue in kidney transplantation is the lack of validated non-invasive biomarkers for monitoring graft function, current biochemical markers (i.e., creatinine) have poor…
2019 American Transplant Congress
Hypertrophy Prediction Model for Contralateral Kidney after Living Donation
K. Okumura¹, K. Tanaka², Y. Hidaka², M. Toyoda³, S. Uekihara³, A. Inadome⁴, H. Yokomizo², S. Yamanaga²
¹Department of Surgery, University of Pittsburgh, Pittsburgh, PA, ²Department of Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, ³Department of Nephrology, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, ⁴Department of Urology, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan
*Purpose: Compensation of contralateral kidney function is well established and many factors have been proposed as risk factors. There is no prediction model to estimate…
2019 American Transplant Congress
Belatacept Based CNI Free Immunosuppression in Pancreas Transplantation. Results at 4 Years
J. Chen, J. Fridell, M. Yaqub, T. Taber, D. MIshler, O. Adebiyi, M. Mujtaba, A. Sharfuddin
Indiana University School of Medicine, Indianapolis, IN
*Purpose: CNI based Immunosuppression is a well known risk factor for worsening renal function. We report our experience in converting Pancreas Transplant recipients from tacrolimus…
2019 American Transplant Congress
Monitoring Inflammatory Cytokine Levels in Kidney Transplant Patients (KTx Pts) with Chronic Antibody Mediated Rejection (cABMR) Treated with Clazakizumab (CLZ, Humanized Anti-IL-6 Monoclonal Antibody)
S. Ge¹, A. Petrosyan¹, M. Chu¹, N. Ammerman², A. Vo², S. C. Jordan², X. Zhang³, M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, ³HLA Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: IL-6 is a pro-inflammatory cytokine involved in KTx rejection. A clinical trial to improve cABMR using CLZ in HLA-sensitized KTx Pts is underway. Inhibition…

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