Articles tagged "Renal failure"

2020 American Transplant Congress
Cyclo(His-Pro) Prevents Against Renal Injury Through Activating Nrf2-Mediated Pathway
J. Moon¹, Y. Kim¹, H. Jung², J. Kim¹, W. Ju³, H. Lee¹, J. Lee⁴, C. Lee⁵, D. Kim¹, Y. Kim¹, S. Yang⁶
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²R&D Center, NovMetaPharma Co., Ltd, Pohang, Gyeongbuk, Korea, Republic of, ³Seoul National University Biomedical Research Institute, Seoul, Korea, Republic of, ⁴Nephrology Clinic, National Cancer Center, Goyang, Korea, Republic of, ⁵Cheju Halla General Hospital, Jeju-do, Korea, Republic of, ⁶Kidney Research Institute, Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: Cyclic(His-Pro) (CHP) is an endogenous cyclic dipeptide that has antioxidative, anti-inflammatory effect via Nuclear factor erythroid 2-related factor (Nrf2) pathway. Endogenous CHP is distributed…
2020 American Transplant Congress
Chronic Kidney Disease Alters the T Cell Response to Murine Cytomegalovirus
R. L. Crepeau¹, H. Li¹, H. S. Koehler², M. L. Ford¹, P. D. Winterberg³
¹Surgery, Emory University, Atlanta, GA, ²Microbiology and Immunology, Emory University, Atlanta, GA, ³Pediatrics, Emory University, Atlanta, GA
*Purpose: We have previously reported that patients with chronic kidney disease (CKD) accumulate memory T cells bearing markers of sustained antigen stimulation and enhanced pro-inflammatory…
2020 American Transplant Congress
Comparative Analysis of Patient Outcomes between Urology-Led versus General Surgery-Led Kidney Transplant Centers
A. Mishra¹, A. Cohen¹, N. Koizumi², A. Ortiz³, K. Pai¹, B. Bullock¹, S. Sureddi¹, J. Ortiz¹
¹The University of Toledo College of Medicine and Life Sciences, Toledo, OH, ²George Mason University, Arlington, VA, ³Albany Medical College, Albany, NY
*Purpose: To assess renal patient outcomes between kidney transplant centers across the United States based on whether their surgical leader was initially trained via the…
2020 American Transplant Congress
Geographic Variation in Listing for Kidney Transplantation: A State-Level Assessment of Access among Patients with End-Stage Renal Disease in the United States
M. N. Mustian, H. Qu, D. Anderson, P. A. MacLennan, R. D. Reed, C. Kale, B. Orandi, B. A. Shelton, V. Kumar, M. Hanaway, J. E. Locke
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Barriers to deceased donor kidney transplantation (DDKT) exist, including referral for transplant and waitlist addition, which may vary regionally. The objective of this study…
2020 American Transplant Congress
Higher State-Level Demand for Renal Transplantation is Associated with Lower Deceased Donor Kidney Transplantation Rate
A. C. Kale, H. Qu, P. MacLennan, R. Reed, D. Anderson, M. N. Mustian, B. Orandi, B. Shelton, V. Kumar, M. J. Hanaway, J. E. Locke
University of Alabama at Birmingham Hospital, Birmingham, AL
*Purpose: Geographic disparities in deceased donor kidney transplantation (DDKT) persist despite increased allocation system oversight and complexity. The association between poor population health and fewer…
2019 American Transplant Congress
Outcomes for Robotic Pancreas Transplants in Obese Candidates
M. Spaggiari, K. A. Tulla, O. T. Okoye, C. Di Bella, P. Di Cocco, J. A. Almario Alvarez, I. G. Tzvetanov, E. Benedetti
University of Illinois at Chicago, Chicago, IL
*Purpose: Pancreas transplantation has evolved to include select overweight and obese diabetes mellitus (DM) patients. A robotic approach can be utilized to treat obese transplant…
2019 American Transplant Congress
Donor Derived Cell Free DNA (dd-cfDNA) May Aid in the Diagnosis of BK Virus Nephropathy
D. Brennan¹, J. Bromberg², J. Yee³, S. Dholakia³, M. Haas⁴
¹Johns Hopkins, Baltimore, MD, ²University of Maryland School of Medicine, Baltimore, MD, ³CareDx, Brisbane, CA, ⁴Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Between 10% and 30% of renal transplant recipients (KTR) develop BK viremia; with 1-10% of KTR developing BK virus associated nephropathy (BKVAN), accounting for…
2019 American Transplant Congress
National Trends in Bariatric Surgical Practice for Patients with End-Stage Renal Disease
K. H. Sheetz¹, K. J. Woodside¹, V. B. Shahinian², J. B. Dimick¹, S. A. Waits¹
¹Department of Surgery, University of Michigan Hospitals and Health System, Ann Arbor, MI, ²Department of Internal Medicine, University of Michigan Hospitals and Health System, Ann Arbor, MI
*Purpose: Despite growing enthusiasm for the use of bariatric surgery in obese patients with end-stage renal disease (ESRD), national practice patterns in this patient population…
2019 American Transplant Congress
Urinary Extracellular Vesicles-Related Protein Biomarkers for the Non-Invasive Monitoring of Rejection in Kidney Transplanted Patients
L. Carreras-Planella¹, I. Bancu², D. Cucchiari³, L. Cañas², J. Juega², M. Franquesa¹, M. Perez-Mir², I. Revuelta³, F. Diekman⁴, R. Lauzurica², F. Borràs¹
¹REMAR-IVECAT Group, Institut Germans Trias i Pujol, Badalona, Spain, ²Nephrology- Renal Transplant Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ³Dept. Nefrologia i Trasplantament Renal, Institut Clínicde Nefrologia i Urologia (ICNU), Hospital Clinic, Barcelona, Spain, ⁴Dept. Nefrologia i Trasplantament Renal, Institut Clínicde Nefrologia i Urologia (ICNU), Hospital Clinic, Badalona, Spain
*Purpose: Chronic kidney rejection is currently the main cause of graft losses. Blood and urine analyses to monitor kidney transplanted patients are not specific, and…
2019 American Transplant Congress
AKI and Long-Term Risk for Cardiovascular Events in Patients after Kidney Transplantation
R. Rahamimov¹, M. Molcho², I. Vahav², E. Mor³, T. Y. van Dijk⁴, B. Rozen-Zvi¹
¹Department of Nephrology, Rabin Medical Center, Petach Tikva, Israel, ²Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ³Department of Transplantation, Rabin Medical Center, Petach Tikva, Israel, ⁴Department of Emergency Medicine, Rabin Medical Center, Petach Tikva, Israel
*Purpose: AKI was found to be associated with increased risk of major cardiovascular events (MACE) in the general population. Patients after kidney transplantation are prone…

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