Articles tagged "Renal failure"

2020 American Transplant Congress
Cyclo(His-Pro) Prevents Against Renal Injury Through Activating Nrf2-Mediated Pathway
J. Moon¹, Y. Kim¹, H. Jung², J. Kim¹, W. Ju³, H. Lee¹, J. Lee⁴, C. Lee⁵, D. Kim¹, Y. Kim¹, S. Yang⁶
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²R&D Center, NovMetaPharma Co., Ltd, Pohang, Gyeongbuk, Korea, Republic of, ³Seoul National University Biomedical Research Institute, Seoul, Korea, Republic of, ⁴Nephrology Clinic, National Cancer Center, Goyang, Korea, Republic of, ⁵Cheju Halla General Hospital, Jeju-do, Korea, Republic of, ⁶Kidney Research Institute, Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: Cyclic(His-Pro) (CHP) is an endogenous cyclic dipeptide that has antioxidative, anti-inflammatory effect via Nuclear factor erythroid 2-related factor (Nrf2) pathway. Endogenous CHP is distributed…
2020 American Transplant Congress
Chronic Kidney Disease Alters the T Cell Response to Murine Cytomegalovirus
R. L. Crepeau¹, H. Li¹, H. S. Koehler², M. L. Ford¹, P. D. Winterberg³
¹Surgery, Emory University, Atlanta, GA, ²Microbiology and Immunology, Emory University, Atlanta, GA, ³Pediatrics, Emory University, Atlanta, GA
*Purpose: We have previously reported that patients with chronic kidney disease (CKD) accumulate memory T cells bearing markers of sustained antigen stimulation and enhanced pro-inflammatory…
2020 American Transplant Congress
Comparative Analysis of Patient Outcomes between Urology-Led versus General Surgery-Led Kidney Transplant Centers
A. Mishra¹, A. Cohen¹, N. Koizumi², A. Ortiz³, K. Pai¹, B. Bullock¹, S. Sureddi¹, J. Ortiz¹
¹The University of Toledo College of Medicine and Life Sciences, Toledo, OH, ²George Mason University, Arlington, VA, ³Albany Medical College, Albany, NY
*Purpose: To assess renal patient outcomes between kidney transplant centers across the United States based on whether their surgical leader was initially trained via the…
2020 American Transplant Congress
Geographic Variation in Listing for Kidney Transplantation: A State-Level Assessment of Access among Patients with End-Stage Renal Disease in the United States
M. N. Mustian, H. Qu, D. Anderson, P. A. MacLennan, R. D. Reed, C. Kale, B. Orandi, B. A. Shelton, V. Kumar, M. Hanaway, J. E. Locke
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Barriers to deceased donor kidney transplantation (DDKT) exist, including referral for transplant and waitlist addition, which may vary regionally. The objective of this study…
2020 American Transplant Congress
Higher State-Level Demand for Renal Transplantation is Associated with Lower Deceased Donor Kidney Transplantation Rate
A. C. Kale, H. Qu, P. MacLennan, R. Reed, D. Anderson, M. N. Mustian, B. Orandi, B. Shelton, V. Kumar, M. J. Hanaway, J. E. Locke
University of Alabama at Birmingham Hospital, Birmingham, AL
*Purpose: Geographic disparities in deceased donor kidney transplantation (DDKT) persist despite increased allocation system oversight and complexity. The association between poor population health and fewer…
2020 American Transplant Congress
Factors Associated with High Mortality in Acute on Chronic Liver Failure Patients Admitted to the Intensive Care Unit, Single Center Experience
O. Mendez Guerrero, D. A. Calle Rodas, E. Cervantes Alvarez, E. Alatorre Arenas, J. Perez Escobar, A. Estanes Hernandez, N. Navarro Alvarez, A. Torre
Hepatology and Liver Transplantation Unit, Gastroenterology department, National Institute of Medical Science and Nutrition Salvador Zubiran, Mexico City, Mexico
*Purpose: ACLF is a newly defined syndrome in the background of a chronic liver disease characterized by acute decompensation, organ failure and high mortality at…
2020 American Transplant Congress
Safety of A2 Incompatible Kidney Transplantation in Donors with Acute Kidney Injury
Y. Al Azzi, L. Liriano-Ward, G. Nair, M. Ajaimy, J. Graham, C. Pynadath, P. Nandigam, A. Colovai, A. Campbell, S. Greenstein, M. Kinkhabwala, J. Rocca, E. Akalin
Abdominal Transplant, Montefiore Medical Center, New York, NY
*Purpose: Kidneys with donor acute kidney injury (AKI) are frequently discarded. We aimed to study the outcomes of A2 incompatible kidney transplantation from donors with…
2020 American Transplant Congress
Delayed Graft Function Adversely Affects Long-Term Survival for Kidney Recipients after Non-Renal Solid-Organ Transplantation
J. A. Reyes, C. Blanton, M. Eerhart, G. Leverson, P. Chlebeck, Y. Yankol, L. Fernandez
Surgery, University of Wisconsin, Madison, WI
*Purpose: End-stage renal disease (ESRD) frequently develops after nonrenal solid-organ transplantation, increasing the number of patients with a prior heart, liver or lung transplant on…
2020 American Transplant Congress
Optimal Timing of Initiating Continuous Renal Replacement Therapy in Patients with Acute Kidney Injury after Liver Transplantation
A. Ren, Z. Li, X. Zhang, R. Deng, Y. Ma
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Acute kidney injury(AKI) is a frequent complication after liver transplantation(LT), and is associated with high mortality. Continuous Renal Replacement Therapy (CRRT) is a blood…
2020 American Transplant Congress
Effects of Tenofovir and Entecavir on Glomerular Kidney Function in Liver Transplant Patients: A Nationwide Cohort Study
J. Lee¹, E. Kim¹, S. Yang¹, S. Kim¹, J. Lee¹, J. Park², H. Choi³, B. Kim², D. Joo¹, S. Kim¹, M. Kim¹
¹Department of Transplantation Surgery, Severance Hospital, Seoul, Korea, Republic of, ²Department of Internal Medicine, Severance Hospital, Seoul, Korea, Republic of, ³Department of Internal Medicine, Gangnam Severance Hospital, Seoul, Korea, Republic of
*Purpose: Entecavir and tenofovir are currently the first-line drugs in liver transplantation (LT) patients for the prevention of hepatitis B virus recurrence. Despite its proven…