ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal failure"

  • 2015 American Transplant Congress

    Causes of Poor Renal Function of Kidney Transplants from Uncontrolled Donation After Cardiac Death Donors (UDCDD)

    M. Molina, E. González, E. Gutiérrez, E. Morales, E. Hernández, A. Sevillano, N. Polanco, J. Cabrera, M. Praga, A. Andres.

    Nephrology, Hospital 12 de Octubre, Madrid, Spain.

    INTRODUCTION: Kidneys grafts from UDCDD have higher ischemia injury. It develops in higher primary non function, lower graft survival and worst renal function compared to…
  • 2015 American Transplant Congress

    Elderly ESRD Patients Have a Significantly Narrowed T-Cell Receptor Repertoire Diversity

    L. Huang,1 A. Langerak,2 I. Wolvers - Tettero,2 R. Meijers,1 C. Baan,1 N. Litjens,1 M. Betjes.1

    1Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands; 2Immunology, Erasmus Medical Center, Rotterdam, Netherlands.

    IntroductionA diverse T-cell receptor (TCR) repertoire is central to effective T-cell mediated immune responses to foreign antigens. Patients suffering from end stage renal disease (ESRD)…
  • 2015 American Transplant Congress

    T Cell Specific Up Regulation of Nrf2 Regulated Antioxidant Response Protects from Kidney Ischemia Reperfusion Injury in Mice

    S. Noel,1 M. Martina,2 S. Bandapalle,1 S. Reddy,3 L. Racusen,2 A. Hamad,2 H. Rabb.1

    1Department of Medicine, Johns Hopkins University, Baltimore, MD; 2Department of Pathology, Johns Hopkins University, Baltimore, MD; 3Department of Pediatrics, University of Illinois, Chicago, IL.

    Background: T lymphocytes mediate important pathophysiological roles during ischemia reperfusion injury (IRI). Transcription factor Nrf2 is protective during experimental kidney IRI and thought to be…
  • 2015 American Transplant Congress

    Dendritic Cells in Kidney Transplant Biopsies Are Associated With Poor Allograft Survival

    I. Batal,1 S. De Serres,1 K. Safa,1 A. Waaga,1 M. Onozato,2 N. Najafian,1 A. Chandraker.1

    1Brigham and Women's Hospital/Harvard Medical School, Boston, MA; 2Massachusetts General Hospital/Harvard Medical School, Boston, MA.

    Background: Long-term renal allograft survival continues to lag behind the progress seen in short-term transplant outcomes. Dendritic cells (DCs) are the most efficient antigen-presenting cells,…
  • 2015 American Transplant Congress

    Severe Sarcopenia and Increased Fat Stores in Pediatric Patients With Liver, Kidney and Intestine Failure

    W. Bush, C. Miller, C. Kubal, J. Fridell, A. Tector, R. Mangus.

    Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Background: Recent research suggests that measures of frailty, such as nutrition status, may be important predictors of surgical and transplant outcomes. The objectively calculated degree…
  • 2015 American Transplant Congress

    Renal Tubular Dysfunction Following Donor Nephrectomy and Its Impact On Residual Kidney Function

    Z. Ahmed,1 C. Rooney,3 C. Turner,2 N. Dalton,2 N. Kessaris,1 N. Mamode.1

    1Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; 2Wellchild Laboratory, St Thomas' Hospital, London, United Kingdom; 3Faculty of Medicine, King's College London, London, United Kingdom.

    Background: Recent publications have described an increasing incidence of end stage renal disease amongst kidney donors. This highlights the paucity of knowledge which exists in…
  • 2015 American Transplant Congress

    Is There a Difference in Patient and Graft Survival in Children Weighing <20 kg Versus Those Weighing >20 kg at the Time of Renal Transplantation?

    P. Chandak,1 J. Stojanovic,2 R. Sivaprakasam,3 N. Mamode,1 F. Calder,1 J. Olsburgh,1 M. Drage,1 C. Callaghan,1 J. Taylor,1 G. Koffman,1 J. Taylor,2 S. Marks,4 N. Kessaris.1

    1Transplant Surgery, Guys and St Thomas Hospitals NHS Trust, London, United Kingdom; 2Nephrology, Evelina Childrens Hospital, London, United Kingdom; 3Transplant Surgery, Royal London Hospital, London, United Kingdom; 4Department of Nephrology and Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.

    Introduction: Renal transplantation (RTx) is the gold standard treatment modality for end-stage kidney disease. There are increased challenges in pediatric renal transplant recipients (pRTR) under…
  • 2015 American Transplant Congress

    Risk of Cause-Specific ESRD in Live Kidney Donors

    S. Anjum, A. Muzaale, A. Massie, S. Bae, D. Segev.

    Johns Hopkins, Baltimore.

    The purpose of this study is to investigate the risk of developing cause-specific ESRD in live kidney donors over time.METHODS: We studied a cohort of…
  • 2015 American Transplant Congress

    1-Year Safety and Efficacy of Eculizumab in Adult aHUS Patients, With or Without a History of Renal Transplant

    C. Legendre,1 J. Kincaid,2 C. Bedrosian,2 C. Loirat.3

    1University Paris Descartes & Hôpital Necker, Paris, France; 2Alexion, Cheshire, CT; 3Assistance Publique–Hôpitaux Paris, Hôpital Robert-Debré, Paris, France.

    Background: Atypical hemolytic-uremic syndrome (aHUS) is a life-threatening, chronic disease of complement-mediated TMA. In aHUS, renal transplantation is associated with post-transplant (TP) TMA and ∼50–70%…
  • 2015 American Transplant Congress

    Cumulative Incidence, Risk Factors for and Impact on Survival of Severe Chronic Kidney Disease After Intestinal Transplantation: Analysis of the SRTR Database

    G. Huard,1 K. Iyer,1 J. Moon,1 L. Schwartz,1 J. Doucette,2 V. Nair,1 T. Schiano.1

    1Recanati-Miller Transplant Institute, Mount Sinai Hospital, New York, NY; 2Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.

    Background: Patient and graft survival rates after intestinal transplantation (ITx) have improved. More ITx recipients achieve long-term survival and are at risk for severe chronic…
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