ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal failure"

  • 2015 American Transplant Congress

    Incidence, Determinants and Outcome of Kidney Transplantation for End Stage Renal Disease After Heart Transplantation

    A. Grupper,1 A. Grupper,1 R. Daly,1 M. Hathcock,2 W. Kremers,2 F. Cosio,1 B. Edwards,1 S. Kushwaha.1

    1William J. von Liebig Transplant Center, Mayo Clinic, Rochester, MN; 2Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN.

    Objectives: Progressive renal failure is a frequent complication following heart transplantation (HTx), is generally attributed to calcineurin inhibitor (CNI) based immunosuppression, and may result in…
  • 2015 American Transplant Congress

    The Synergistic Effect of Class II HLA Epitope-Mismatch and Non-Adherence on Acute Rejection and Graft Survival

    C. Wiebe,1,2 T. Nevins,3 W. Robiner,3,4 W. Thomas,5 A. Matas,6 P. Nickerson.1,2,8

    1Medicine, University of Manitoba, Winnipeg, MB, Canada; 2Transplant Immunology, Diagnostic Services of Manitoba, Winnipeg, MB, Canada; 3Pediatrics, University of Minnesota, Minneapolis, MN; 4Medicine, University of Minnesota, Minneapolis, MN; 5Public Health, University of Minnesota, Minneapolis, MN; 6Surgery, University of Minnesota, Minneapolis, MN; 7Immunology, University of Manitoba, Winnipeg, MB, Canada.

    Predicting long-term outcomes in renal transplant recipients is essential to optimize medical therapy and determine the frequency of post-transplant pathologic and serologic monitoring. Non-adherence and…
  • 2015 American Transplant Congress

    Comparison of Markers of Inflammation Between Dialysis Patients With and Without Failed Kidney Allograft

    R. Villca-Gonzales, R. Vazquez-Apodaca, D. Hernandez-Ramirez, L. Llorente-Peters, J. Alberu, L. Morales-Buenrostro.

    Nephrology and Transplantation, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City, DF, Mexico.

    BACKGROUND: The rates of morbidity and mortality in patients with a failed kidney transplant are higher than dialysis patients who had never been transplanted. The…
  • 2015 American Transplant Congress

    Acute Kidney Injury in Kidney Transplant Patients According to the KDIGO Criteria

    T. Filiponi, A. Silva-Filho, E. Tonato, L. Requiao-Moura, A. Matos, E. Arruda, R. Chinen, L. Pires, M. Durão Junior.

    Kidney Transplantation, Albert Einstein Hospital, Sao Paulo, Brazil.

    Purpose.To assess the incidence, risk factors and outcomes associated with acute kidney injury (AKI) in kidney transplant in patients using KDIGO classification. Methods- Retrospective cohort…
  • 2015 American Transplant Congress

    Causes of Poor Renal Function of Kidney Transplants from Uncontrolled Donation After Cardiac Death Donors (UDCDD)

    M. Molina, E. González, E. Gutiérrez, E. Morales, E. Hernández, A. Sevillano, N. Polanco, J. Cabrera, M. Praga, A. Andres.

    Nephrology, Hospital 12 de Octubre, Madrid, Spain.

    INTRODUCTION: Kidneys grafts from UDCDD have higher ischemia injury. It develops in higher primary non function, lower graft survival and worst renal function compared to…
  • 2015 American Transplant Congress

    Elderly ESRD Patients Have a Significantly Narrowed T-Cell Receptor Repertoire Diversity

    L. Huang,1 A. Langerak,2 I. Wolvers - Tettero,2 R. Meijers,1 C. Baan,1 N. Litjens,1 M. Betjes.1

    1Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands; 2Immunology, Erasmus Medical Center, Rotterdam, Netherlands.

    IntroductionA diverse T-cell receptor (TCR) repertoire is central to effective T-cell mediated immune responses to foreign antigens. Patients suffering from end stage renal disease (ESRD)…
  • 2015 American Transplant Congress

    T Cell Specific Up Regulation of Nrf2 Regulated Antioxidant Response Protects from Kidney Ischemia Reperfusion Injury in Mice

    S. Noel,1 M. Martina,2 S. Bandapalle,1 S. Reddy,3 L. Racusen,2 A. Hamad,2 H. Rabb.1

    1Department of Medicine, Johns Hopkins University, Baltimore, MD; 2Department of Pathology, Johns Hopkins University, Baltimore, MD; 3Department of Pediatrics, University of Illinois, Chicago, IL.

    Background: T lymphocytes mediate important pathophysiological roles during ischemia reperfusion injury (IRI). Transcription factor Nrf2 is protective during experimental kidney IRI and thought to be…
  • 2015 American Transplant Congress

    Dendritic Cells in Kidney Transplant Biopsies Are Associated With Poor Allograft Survival

    I. Batal,1 S. De Serres,1 K. Safa,1 A. Waaga,1 M. Onozato,2 N. Najafian,1 A. Chandraker.1

    1Brigham and Women's Hospital/Harvard Medical School, Boston, MA; 2Massachusetts General Hospital/Harvard Medical School, Boston, MA.

    Background: Long-term renal allograft survival continues to lag behind the progress seen in short-term transplant outcomes. Dendritic cells (DCs) are the most efficient antigen-presenting cells,…
  • 2015 American Transplant Congress

    Severe Sarcopenia and Increased Fat Stores in Pediatric Patients With Liver, Kidney and Intestine Failure

    W. Bush, C. Miller, C. Kubal, J. Fridell, A. Tector, R. Mangus.

    Transplant Division, Dept of Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Background: Recent research suggests that measures of frailty, such as nutrition status, may be important predictors of surgical and transplant outcomes. The objectively calculated degree…
  • 2015 American Transplant Congress

    Renal Tubular Dysfunction Following Donor Nephrectomy and Its Impact On Residual Kidney Function

    Z. Ahmed,1 C. Rooney,3 C. Turner,2 N. Dalton,2 N. Kessaris,1 N. Mamode.1

    1Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; 2Wellchild Laboratory, St Thomas' Hospital, London, United Kingdom; 3Faculty of Medicine, King's College London, London, United Kingdom.

    Background: Recent publications have described an increasing incidence of end stage renal disease amongst kidney donors. This highlights the paucity of knowledge which exists in…
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