Articles tagged "Renal failure"

2016 American Transplant Congress
Acute Kidney Injury (AKI) Associated with Chronic Kidney Disease (CKD) in Paediatric Non-Kidney Transplant Recipients.
C. Williams,^1,2 K. Borges,² T. Banh,² J. Vasilevska-Ristovska,² R. Chanchlani,^1,2 V. Ng,^1,2 A. Dipchand,^1,2 M. Solomon,^1,2 D. Hebert,^1,2 S. Kim,^1,3 B. Astor,⁴ R. Parekh.^1,2,3
¹University of Toronto, Toronto, Canada; ²Hospital for Sick Children, Toronto, Canada; ³University Health Network, Toronto, Canada; ⁴University of Wisconsin, Madison.
Background: Kidney dysfunction is common after solid organ transplantation; however, rates of post-transplant AKI and CKD in children are unknown.Objective: Determine rates of AKI and…
2016 American Transplant Congress
Renal Outcome with Eculizumab in Patients with aHUS with Native and Transplanted Kidneys: Pooled Analysis of 100 Patients.
C. Legendre,¹ J. Campistol,² T. Feldkamp,³ J. Wang,⁴ G. Remuzzi,⁵ L. Weekers,⁶ N. Sheerin.⁷
¹Université Paris Descartes & Hôpital Necker, Paris, France; ²Hospital Clinic, University of Barcelona, Barcelona, Spain; ³University Hospital Schleswig-Holstein, Kiel, Germany; ⁴Alexion Pharmaceuticals, Inc., Cheshire, CT; ⁵IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, Italy; ⁶CHU de Liège, Liège, Belgium; ⁷Newcastle University, Newcastle upon Tyne, United Kingdom.
Purpose: aHUS often progresses to ESRD and requires transplant (tx). Eculiumab (ECU), a terminal complement inhibitor, inhibits TMA irrespective of tx status. We evaluated outcomes…
2016 American Transplant Congress
Concordance Between Pancreatic Rejection and Kidney Rejection and Kidney Survival in Simultaneous Pancreas Kidney Transplantation.
I. Moinuddin, T. Taber, M. Yaqub, D. Mishler, O. Adebiyi, J. Chen, M. Goble, J. Powelson, J. Fridell, A. Sharfuddin.
Transplant Nephrology, Indiana University, Indianapolis, IN.
Purpose: It is not known whether pancreas rejection is associated with increased kidney rejection. Also, it is not known whether pancreas survival affects kidney and…
2016 American Transplant Congress
Immunological Ageing-Related Expansion of Highly Differentiated CD4⁺CD28null T Cells Is Associated with a Lower Risk for Early Acute Rejection After Renal Transplantation.
B. Dedeoglu, R. Meijers, M. Klepper, D. Hesselink, C. Baan, N. Litjens, M. Betjes.
Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Centre, Rotterdam, Netherlands.
Background: End-stage renal disease patients have a dysfunctional, prematurely aged peripheral T-cell system. Here we hypothesized that the degree of premature T-cell ageing before kidney…
2016 American Transplant Congress
End Stage Renal Disease Patients Have a Skewed T Cell Receptor Vbeta Repertoire.
L. Huang,¹ A. Langerak,² I. Wolvers - Tettero,² R. Meijers,¹ C. Baan,¹ N. Litjens,¹ M. Betjes.¹
¹Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; ²Immunology, Erasmus University Medical Center, Rotterdam, Netherlands.
IntroductionEnd stage renal disease (ESRD) is associated with a defective T-cell mediated immunity, resembling premature T-cell ageing. A diverse T-cell receptor Vbeta (TCR Vβ) repertoire…
2016 American Transplant Congress
Survival Advantage in the Elderly with Kidney Transplantation.
G. Spanos,¹ N. Duncan,¹ P. Brookes,¹ D. Goodall,¹ K. Koutroutsos,¹ E. Evangelou,² M. Loucaidou.¹
¹Imperial College Renal Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; ²Department of Biostatistics and Epidemiology, Imperial College London, London, United Kingdom.
Background: Patients with established renal failure (ERF) are aging. Of patients starting dialysis at our centre a third and a half are over the age…
2016 American Transplant Congress
Kidney Transplantation Offers a Significant Survival Advantage Compared to Waitlisting, a Single Centre Experience.
G. Spanos,¹ N. Duncan,¹ P. Brookes,¹ S. Singh,¹ D. Goodall,¹ D. Moutzouris,¹ E. Evangelou,² M. Loucaidou.¹
¹Imperial College Renal Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; ²Department of Biostatistics and Epidemiology, Imperial College London, London, United Kingdom.
Background: Kidney transplantation is associated with lower mortality and improved quality of life for patients with end stage renal disease (ESRD). Survival in dialysis and…
2016 American Transplant Congress
Is MELD Score a Significant Predictor of Post-Transplant Mortality? An Old Issue with Simple Answer.
A. Rahnemai-Azar,¹ J. Perkins,¹ M. Montenovo,¹ S. Rayhill,¹ R. Bakthavatsalam,¹ N. Leca,² C. Blosser,² I. Di Castro,² R. Bhattacharya,³ J. Reyes,¹ L. Sibulesky.¹
¹Surgery, University of Washington, Seattle, WA; ²Nephrology, University of Washington, Seattle, WA; ³Hepatology, University of Washington, Seattle, WA.
The predictive value of the Model for End-Stage Liver Disease (MELD) score for post-transplant survival has been under constant debate. Some investigators tried to introduce…
2016 American Transplant Congress
Prolonged Pre-Transplant Dialysis Duration Reverses the “Nephroprotective Effect” in Simultaneous Liver-Kidney Transplant Recipients.
M. Casey, X. Wen, A. Santos, S. Rehman, K. Womer.
University of Florida, Gainesville.
Past literature has suggested that simultaneous liver-kidney(SLK) transplant recipients may experience a nephroprotective effect compared to kidney(Ki) alone transplant recipients. Since hepatorenal syndrome is a…
2016 American Transplant Congress
The Impact of Kidney Donor Profile Index (KDPI) on Rates of Delayed Graft Function (DGF).
T. Zens, G. Leverson, R. Redfield, P. Chlebeck, L. Zitur, D. Kaufman, L. Fernandez.
Surgery, University of Wisconsin, Madison, WI.
Introduction: Delayed graft function (DGF) is the need for dialysis within the first 7 days after kidney transplantation. Immunologic and non-immunologic donor and recipient factors…