Articles tagged "Renal dysfunction"

2020 American Transplant Congress
Sparing the Nephron in Liver Transplant Recipients with Antithymocyte Bridging: A Four Year Experience
N. Wilson, H. Kuzaro, N. Parrish, S. A. Shah, N. Anwar, R. R. Alloway, S. Tremblay, T. E. Kaiser
U Cincinnati, Cincinnati, OH
*Purpose: Renal function decline after liver transplant (LT) remains a significant issue. Using antithymocyte globulin (rATG) to delay tacrolimus (TAC) initiation may impact renal deterioration;…
2020 American Transplant Congress
Kidneys from AKI Donors with Poor Long-Term Outcomes Present an Impaired Protein Expression for Cellular Stress and Repair
F. Neri¹, M. Lo Faro¹, C. Boffa¹, T. Surik¹, M. Kaisar¹, E. J. Sharples², J. P. Hunter¹, J. Lindeman³, R. Ploeg¹
¹Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom, ²Oxford Transplant Centre, Oxford, United Kingdom, ³Department of Vascular Surgery, Leiden University Medical Center (LUMC), Leiden, Netherlands
*Purpose: The utilization of kidneys from donors with acute kidney injury (AKI) is often limited by unpredictable post-transplantation outcomes. The aim of our study was…
2020 American Transplant Congress
Impact of Worsening Renal Function While Waiting for Heart Transplantation
A. Kumar¹, C. P. Thomas²
¹Internal Medicine, University of Vermont, Burlington, VT, ²Internal Medicine, University of Iowa, Iowa City, IA
*Purpose: Pre transplant renal function has been shown to be a strong predictor of long term renal as well as patient survival in heart transplant…
2020 American Transplant Congress
Time for Change: Assessment of Renal Transplant Artery Stenosis with N.A.T.I.V.E. True-F.I.S.P. and N.A.T.I.V.E. G.R.E
J. C. Infante¹, A. Mattiazzi², M. Morsi³, G. Guerra², M. J. Defreitas⁴, J. Chandar⁴, L. J. Chen³, G. W. Burke³, J. Figueiro³, G. Ciancio³
¹Radiology, University of Miami, Miami, FL, ²Department of Medicine, Division of Nephrology, University of Miami / Miami Transplant Institute, Miami, FL, ³Department of Surgery, University of Miami / Miami Transplant Institute, Miami, FL, ⁴Department of Pediatrics, Division of Nephrology, University of Miami, Miami, FL
*Purpose: Non-contrast MRA can be fraught with artifact and lack of signal both in areas of stenosis as well as normal vessels. Therefore, it is…
2020 American Transplant Congress
Improved Kidney Function Post Lung Transplant with Intravenous Tacrolimus Avoidance
C. Burt¹, A. Feist¹, K. Afshar², L. Awdishu¹, M. Mariski¹, J. Kozuch¹, G. Yung², E. Golts³
¹Pharmacy, UC San Diego Health, San Diego, CA, ²Pulmonology, UC San Diego Health, San Diego, CA, ³Cardiothoracic Surgery, UC San Diego Health, San Diego, CA
*Purpose: Tacrolimus (TAC) poses a dose-dependent risk of acute kidney injury (AKI) as well as chronic kidney disease (CKD) post-transplant. In 2017, our institution’s lung…
2020 American Transplant Congress
Incidence of Chronic Kidney Disease after Liver Transplantation Using Measured GFR
N. R. Mazumder¹, J. Levitsky¹, G. Saracino², G. Klintmalm³, J. Trotter², S. Asrani²
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Transplant Hepatology, Baylor University Medical Center Dallas, Dallas, TX, ³Transplant Surgery, Baylor University Medical Center Dallas, Dallas, TX
*Purpose: Historical rates of ESRD after LT are 8% (1 year) and 18% (5 years) (Ojo NEJM 2003). However, these rates were based older estimates…
2020 American Transplant Congress
Avoiding Surveillance Biopsy: How? When? Now!
A. Ang¹, C. Schieve², S. Rose², C. Kew¹, M. R. First², R. B. Mannon¹
¹School of Medicine, University of Alabama, Birmingham, Birmingham, AL, ²Transplant Genomics Inc., Mansfield, MA
*Purpose: The TruGraf™ blood test measures a specific gene expression signature in the peripheral blood mononuclear cells to enable noninvasive serial assessment of kidney transplant…
2020 American Transplant Congress
Large Academic Center Experience with Treatment of Suspected/Confirmed Kidney Transplant Active Antibody Mediated Rejection
J. T. Reece¹, B. A. Steiner², V. Bhoj¹, N. Aqui¹, R. D. Bloom³, J. Trofe-Clark⁴
¹Transfusion Medicine Div, Univ of Pennsylvania, Philadelphia, PA, ²Pharmacy, Hosp of Univ of Pennsylvania, Philadelphia, PA, ³Renal Div, Univ of Pennsylvania, Philadelphia, PA, ⁴Pharmacy, Hospital of University of Pennsylvania, Philadelphia, PA
*Purpose: Therapeutic plasma exchange (TPE) and intravenous immunoglobulin (IVIG) are common active antibody mediated rejection (ABMR) treatments in kidney transplant recipients (KTRs), but with unclear…
2020 American Transplant Congress
ANG-3777, A Hepatic Growth Factor Mimetic, Attenuates Post-Transplant Renal Dysfunction in Rats
P. Narayan, I. D. Goldberg
Angion Biomedica, Uniondale, NY
*Purpose: ANG-3777, a small-molecule mimetic of hepatocyte growth factor (HGF), has the potential to exert antifibrotic and nephroprotective effects. A rat model of renal transplantation…
2020 American Transplant Congress
Time-Zero Histology Correlates with Donor Characteristics but Does Not Predict Short-Term Outcomes in Kidney Transplantation
S. Raza, G. Agarwal, D. Anderson, M. Deierhoi, H. Fatima, M. Hanaway, J. Locke, P. MacLennan, B. Orandi, C. Young, R. Mannon, M. Seifert
University of Alabama School of Medicine, Birmingham, AL
*Purpose: Time-zero biopsies provide important information about baseline histology but their clinical utility compared to other non-invasive predictors is unclear. Our center performs universal time-zero…