Articles tagged "Renal dysfunction"

2016 American Transplant Congress
Renal Allograft Outcomes with Renal Artery Angioplasty and/or Stenting in Transplant Renal Artery Stenosis.
E. Tantisattamo,¹ A. Chokechanachaisakul,² S. Pitukweerakul,³ P. Ratanasrimetha,⁴ A. Shetty,² O. Traitanon,⁵ L. Gallon.²
¹Oakland University William Beaumont School of Medicine, Royal Oak, MI; ²Northwestern University, Chicago, IL; ³Presence St. Francis Hospital, Evanston, IL; ⁴Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; ⁵Thammasart University Hospital, Pathumthani, Thailand.
Background: The renal allograft function and blood pressure (BP) control after renal artery angioplasty±stenting for transplant renal artery stenosis (TRAS) is unclear. We aim to…
2016 American Transplant Congress
Acute Kidney Injury and Chronic Kidney Disease in Donation After Circulatory Death Liver Transplantation: UK Single Centre Study.
I. Umbro,^1,2 F. Tinti,^1,2 F. Evison,³ A. Sharif,⁴ B. Gunson,⁵ A. Mitterhofer,² J. Ferguson,¹ P. Muiesan.¹
¹The Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; ²Nephrology and Dialysis Unit, Sapienza University of Rome, Rome, Italy; ³Department of Health Informatics, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom; ⁴Department of Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom; ⁵NIHR Birmingham Liver Biomedical Research Unit and Centre for Liver Research, University of Birmingham, Birmingham, United Kingdom.
Aim of the study is to assess the incidence of acute kidney injury (AKI) and chronic kidney disease (CKD) after liver transplantation (LT) in DCD…
2016 American Transplant Congress
Metabolomic Profiling of Individuals with Failing Kidney Allograft.
R. Bassi,^1,2 M. Niewczas,³ L. Biancone,⁵ S. Bussolino,⁵ A. Lin,⁴ A. Chandraker,⁶ P. Fiorina.^1,2
¹Nephrology, Boston Children's Hospital, Boston; ²Transplant Medicine, IRCCS San Raffaele Hospital, Milan, Italy; ³Genetics and Epidemiology, Joslin Diabetes Center, Boston; ⁴Radiology, Brigham and Women's Hospital, Boston; ⁵Nephrology and Transplantation, San Giovanni Battista Hospital, Turin, Italy; ⁶Transplantation Research Center, Brigham and Women's Hospital, Boston.
Alteration of certain metabolites may play a role in the pathophysiology of renal allograft disease. To explore metabolome abnormalities in individuals with a failing kidney…
2016 American Transplant Congress
Outcomes of Pediatric en Bloc Kidney (PeB) Grafts After Loss of a Single Kidney.
C. Santhanakrishnan, R. Perez, J. McVicar, J. Sageshima, C. Troppmannn.
Division of Transplantation, Dept of Surgery, Univ of Calif Davis Medical Center, Sacramento, CA.
Background: Transplantation (Tx) of PeB kidney grafts has been shown to result in good long-term outcomes. However, the fate of PeB grafts that suffer loss…
2016 American Transplant Congress
Fluctuation of Renal Function During the First Year Is Associated with Negative Impact on Long-Term Kidney Graft Survival: A Retrospective, Propensity Score-Matched Study.
H. Choi,¹ D. Joo,^2,3 M. Song,⁴ M. Kim,^2,3 Y. Kim,^2,3 B. Kim.^1,3
¹Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea; ²Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; ³The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; ⁴Department of Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.
Background: Post-transplant renal function in the first year has been reported to predict long-term renal graft survival. The present study examined whether the fluctuation of…
2016 American Transplant Congress
A Comprehensive Biomarker Study to Compare Tacrolimus and Mycophenolic Acid versus Half-Dose Tacrolimus and Everolimus in De Novo Kidney Transplant Patients in the Novartis US92 Study.
J. Klepacki,¹ J. Klawitter,¹ J. Klawitter,¹ A. Karimpour-fard,² E. Anderson,¹ G. Ingle,³ D. Patel,³ K. Johnson,⁴ D. Cibrik,⁴ U. Christians.¹
¹University of Colorado Denver, Aurora, CO; ²University of Colorado Denver, Aurora, CO; ³Novartis Pharmaceuticals, East Hannover, NJ; ⁴University of Michigan, Ann Arbor, MI.
In this exploratory biomarker sub-study, a comprehensive combined targeted/ non-targeted metabolomics and targeted proteomics approach was used to assess potential differences between the everolimus+ low-dose…
2016 American Transplant Congress
Renal Dysfunction at 12 Months Is Not Associated with Everolimus Exposure in De Novo Renal Transplant Recipients.
F. Shihab,¹ Y. Qazi,² S. Mulgaonkar,³ K. McCague,⁴ D. Patel,⁴ V. Peddi,⁵ D. Shaffer.⁶
¹University of Utah, Salt Lake City, UT; ²University of Southern California, Los Angeles, CA; ³Barnabas Health, West Orange, NJ; ⁴Novartis Pharmaceuticals Corporation, East Hanover, NJ; ⁵California Pacific Medical Center, San Francisco, CA; ⁶Vanderbilt University, Nashville, TN.
Renal dysfunction at 1 year post-transplantation is associated with poor graft outcome. Here, we assess post-transplant renal function associated with everolimus (EVR) and tacrolimus (TAC)…
2015 American Transplant Congress
Isolated Microcirculation Inflammation Negatively Impacts Renal Graft Function at 5 Years
A. Chapelet,¹ M. Touzot,¹ M. Fournier,² A. Cesbron,³ K. Renaudin,⁴ A. Moreau,⁴ E. Morelon,⁵ D. Anglicheau,⁶ M. Giral.¹
¹Institut de Transplantation Urologie Néphrologie, CHU Nantes, Nantes, France; ²EA 4275 SPHERE—Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences, University of Nantes, Nantes, France; ³Etablissement Français du Sang (EFS), Nantes, France; ⁴Service d'Anatomie et Cytologie Pathologiques, CHU Nantes, Nantes, France; ⁵Service de Néphrologie, Transplantation et Immunologie Clinique, Hôpital Edouard Herriot, Lyon, France; ⁶Service de Transplantation Rénale et de Soins Intensifs, Hôpital Necker, Paris, France.
BACKGROUND: Microcirculation inflammation (MI, ie: glomerulitis (g) and peritubular capillaritis (ptc)) associated with anti-HLA Donor Specific Antibody (DSA) with or without C4d deposits in ptc…
2015 American Transplant Congress
Lung Transplant Patients With Elevated Baseline Pulmonary Arterial Pressures Are More Likely to Recover from Post-Transplant Acute Kidney Injury
B. Stephany,¹ E. Wehbe,² M. Budev.³
¹Nephrology & Hypertension, Cleveland Clinic, Cleveland, OH; ²Nephrology, Wichita, KS; ³Pulmonary, Allergy & Critical Care, Cleveland Clinic, Cleveland, OH.
Purpose: Elevated pre-operative pulmonary arterial pressures predict acute kidney injury (AKI) after lung transplant. It is unknown if the elevated pulmonary pressures predict recovery from…
2015 American Transplant Congress
Renal Function Following Basiliximab Induction in Liver Transplant Recipients
J. Hagopian, T. Horwedel, L. Bowman, K. Collins, M. Doyle.
Washington University School of Medicine, St. Louis.
Purpose: Reports of the use of antibody induction to delay the start of calcineurin inhibitor therapy postoperatively in patients with renal insufficiency at the time…