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Articles tagged "Renal dysfunction"

  • 2016 American Transplant Congress

    Fluctuation of Renal Function During the First Year Is Associated with Negative Impact on Long-Term Kidney Graft Survival: A Retrospective, Propensity Score-Matched Study.

    H. Choi,1 D. Joo,2,3 M. Song,4 M. Kim,2,3 Y. Kim,2,3 B. Kim.1,3

    1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea; 2Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; 3The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; 4Department of Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.

    Background: Post-transplant renal function in the first year has been reported to predict long-term renal graft survival. The present study examined whether the fluctuation of…
  • 2016 American Transplant Congress

    A Comprehensive Biomarker Study to Compare Tacrolimus and Mycophenolic Acid versus Half-Dose Tacrolimus and Everolimus in De Novo Kidney Transplant Patients in the Novartis US92 Study.

    J. Klepacki,1 J. Klawitter,1 J. Klawitter,1 A. Karimpour-fard,2 E. Anderson,1 G. Ingle,3 D. Patel,3 K. Johnson,4 D. Cibrik,4 U. Christians.1

    1University of Colorado Denver, Aurora, CO; 2University of Colorado Denver, Aurora, CO; 3Novartis Pharmaceuticals, East Hannover, NJ; 4University of Michigan, Ann Arbor, MI.

    In this exploratory biomarker sub-study, a comprehensive combined targeted/ non-targeted metabolomics and targeted proteomics approach was used to assess potential differences between the everolimus+ low-dose…
  • 2016 American Transplant Congress

    Renal Dysfunction at 12 Months Is Not Associated with Everolimus Exposure in De Novo Renal Transplant Recipients.

    F. Shihab,1 Y. Qazi,2 S. Mulgaonkar,3 K. McCague,4 D. Patel,4 V. Peddi,5 D. Shaffer.6

    1University of Utah, Salt Lake City, UT; 2University of Southern California, Los Angeles, CA; 3Barnabas Health, West Orange, NJ; 4Novartis Pharmaceuticals Corporation, East Hanover, NJ; 5California Pacific Medical Center, San Francisco, CA; 6Vanderbilt University, Nashville, TN.

    Renal dysfunction at 1 year post-transplantation is associated with poor graft outcome. Here, we assess post-transplant renal function associated with everolimus (EVR) and tacrolimus (TAC)…
  • 2016 American Transplant Congress

    Renal Risk Index and Acute Kidney Injury in Liver Transplant Patients.

    J. Neal, Y. Sun, J. Erley, J. Shen, C. Sonnenday, P. Sharma, J. Park.

    University of Michigan, Ann Arbor, MI.

    Purpose: Renal risk index (RRI) has been validated in liver transplant (LT) to predict post-transplant ESRD. We examined the clinical utility of RRI as a…
  • 2016 American Transplant Congress

    Renal Function Decline Is Higher in the First Year After Liver Transplantation: Final Results from the Italian Observational Study SURF.

    A. Giacomoni,1 M. Cescon,2 G. Magini,3 F. Picciotto,4 U. Cillo,5 M. Senzolo,5 G. Vennarecci,6 P. De Simone.7

    1AO Niguarda, Milano, Italy; 2AO S.Orsola-Malpighi, Bologna, Italy; 3AO Papa Giovanni XXIII, Bergamo, Italy; 4AO Cardarelli, Napoli, Italy; 5AOU di Padova, Padova, Italy; 6O S.Camillo, Roma, Italy; 7AOU Cisanello, Pisa, Italy.

    SURF registry was designed to investigate the evolution of renal function in Italian adult liver transplant (LT) recipients by: exploring the prevalence of chronic kidney…
  • 2016 American Transplant Congress

    Liver Recipient with Renal Dysfunction: Liver Only or Simultaneous Liver-Kidney Transplant?

    K. Yadav, T. Pruett, R. Kandaswamy, W. Payne, L. Zhang, S. Chinnakotla.

    University of Minnesota, Minneapolis, MN.

    Background: The OPTN listing criteria for Simultaneous liver-kidney transplant (SLK) are not well defined. There are concerns about rising numbers of SLKs, which take kidneys…
  • 2016 American Transplant Congress

    The UK Kidney Donor Risk Index Score Predicts the Development of TRAS Post Deceased Donor Transplantation.

    M. Willicombe, A. Baheerathan, S. Moser, A. McLean, M. Hammady, W. Gedroyc, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Introduction: Transplant renal artery stenosis (TRAS) is a heterogeneous disorder with different subtypes and aetiologies, which include traditional cardiovascular and transplant specific risk factors. Whether…
  • 2015 American Transplant Congress

    Prevalence, Risk Factors, and Clinical Management of Chronic Renal Dysfunction in Heart Transplant Recipients

    K. Xhima, O. Famure, Y. Li, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.

    Background: Chronic kidney disease (CKD) is a frequent complication after heart transplantation. The magnitude of post-transplant CKD makes it necessary to characterize patients at increased…
  • 2015 American Transplant Congress

    Moderate Rejection Episode of Face Transplant After mTOR Conversion to Preserve Renal Function

    R. Barth,1 B. Bojovic,1 J. Woodall,1 M. Uluer,1 C. Drachenberg,1 C. Shaffer,1 N. Kelly,1 E. Rodriguez,2 S. Bartlett.1

    1University of Maryland School of Medicine, Baltimore; 2New York Medical University, New York City.

    Face and hand vascularized composite allografts (VCA) have demonstrated durable graft survivals with conventional immunosuppression but with the appearance of renal dysfunction. Management strategies that…
  • 2015 American Transplant Congress

    Six-Month Urinary CCL2 Levels Predict Long-Term Renal Allograft Outcome

    J. Ho,1 D. Rush,1 A. Gao,1 H. Hopfer,2 C. Wiebe,1 P. Nickerson,1 S. Schaub,2 P. Hirt-Minkowski.2

    1Internal Medicine, Nephrology, University of Manitoba, Winnipeg, MB, Canada; 2Transplantation Immunology & Nephrology, University Hospital, Basel, Basel, Switzerland.

    Graft loss is a major cause of morbidity and mortality. We have shown that 6-month urine CCL2 is an independent predictor for death-censored graft loss.…
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