Articles tagged "Renal dysfunction"

2016 American Transplant Congress
Association of Smoking Habits with Comorbidity 15 Years After Liver Transplantation.
S. Pischke,³ M. Lege,¹ L. Fischer,² U. Herden,² A. Lohse,³ B. Nashan,² M. Sterneck.¹
¹University Transplant Center, University Hospital Hamburg Eppendorf, Hamburg, Germany; ²Department of Hepatobiliary Surgery and Transplantation, University Hospital Hamburg Eppendorf, Hamburg, Germany; ³Department of Medicine, University Hospital Hamburg Eppendorf, Hamburg, Germany.
Background and aimsThe survival rate of liver transplant (OLT) recipients has strongly improved over the last years. Here we investigate the association between long term…
2016 American Transplant Congress
Identification of Donor HLA-Specific Antibodies as a Risk Factor for Graft Dysfunction and Failure Following BK Virus Associated Nephropathy.
E. Abuhelaiqa, S. Salvatore, J. Lee, J. Lee, V. Sharma, T. Muthukumar, S. Seshan, M. Suthanthiran, D. Dadhania.
Transplantation Medicine, Weill Cornell Medicine, New York, NY.
Background: BK virus associated nephropathy (BKVN) has emerged as a significant cause of graft dysfunction and graft failure. Identification of risk factors for graft dysfunction…
2016 American Transplant Congress
Slipping Through the Cracks: Late Onset BK Viremia.
J. Gandhi,¹ M. Mackenzie,¹ D. DeWolfe,² F. Cardarelli,³ M. Pavlakis,³ C. Tan.^1,4
¹Center for Virology & Vaccine Research, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA; ²Division of Nephrology, BIDMC, Boston, MA; ³The Transplant Institute, BIDMC, Boston, MA; ⁴Division of Infectious Disease, BIDMC, Boston, MA.
Introduction: Most studies indicate that viremia caused by BK virus (BKV), the step preceding BKV associated nephropathy (BKVN) in kidney transplant recipients (KTRs), occurs within…
2016 American Transplant Congress
Conversion from Tacrolimus to Belatacept in Pancreas Transplant Alone Recipients with Chronic Kidney Disease.
A. Sharfuddin, J. Chen, M. Yaqub, T. Taber, J. Powelson, D. Mishler, M. Goble, J. Fridell, O. Adebiyi, M. Mujtaba.
Medicine/Nephrology & Surgery/Transplant, Indiana University, Indianapolis.
Background: CNI toxicity is a well known risk factor for chronic kidney disease and ESRD in organ transplants. We report our experience in converting Pancreas…
2016 American Transplant Congress
Levels of VEGF-C, PLGF and Follistatin at 12 Months Post Transplantation Are Associated with Increased Risk for Long Term Progressive Renal Dysfunction.
G. Dreyer,¹ J. de Fijter,¹ D. Briscoe,² K. Daly,² M. Reinders.¹
¹Nephrology, LUMC, Leiden, Netherlands; ²Transplantation Research Center, Boston Children's Hospital, Boston, MA.
*contributed equallyIntroduction Integrity of the microvasculature is critical for long term survival after solid organ transplantation. We hypothesize that biomarkers of endothelial injury and repair…
2016 American Transplant Congress
AT1R Antibodies at 1-Year Negatively Impact 5-Year Native Renal Function in Liver Transplant Recipients.
J. O'Leary,¹ A. Philippe,² H. Heidecke,² R. Freeman,¹ L. Jennings,¹ R. Catar,² G. Klintmalm,¹ D. Dragun.²
¹Baylor Simmons Transplant Insttute, Baylor University Medical Center, Dallas, TX; ²Internal Medicine, Charite, Berlin, Germany.
Angiotensin II Type-1 Receptor (AT1R) antibodies have been associated with pulmonary hypertension, renal allograft loss, and fibrosis progression in liver allograft recipients especially if combined…
2016 American Transplant Congress
Renal Allograft Outcomes with Renal Artery Angioplasty and/or Stenting in Transplant Renal Artery Stenosis.
E. Tantisattamo,¹ A. Chokechanachaisakul,² S. Pitukweerakul,³ P. Ratanasrimetha,⁴ A. Shetty,² O. Traitanon,⁵ L. Gallon.²
¹Oakland University William Beaumont School of Medicine, Royal Oak, MI; ²Northwestern University, Chicago, IL; ³Presence St. Francis Hospital, Evanston, IL; ⁴Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; ⁵Thammasart University Hospital, Pathumthani, Thailand.
Background: The renal allograft function and blood pressure (BP) control after renal artery angioplasty±stenting for transplant renal artery stenosis (TRAS) is unclear. We aim to…
2016 American Transplant Congress
Acute Kidney Injury and Chronic Kidney Disease in Donation After Circulatory Death Liver Transplantation: UK Single Centre Study.
I. Umbro,^1,2 F. Tinti,^1,2 F. Evison,³ A. Sharif,⁴ B. Gunson,⁵ A. Mitterhofer,² J. Ferguson,¹ P. Muiesan.¹
¹The Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; ²Nephrology and Dialysis Unit, Sapienza University of Rome, Rome, Italy; ³Department of Health Informatics, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom; ⁴Department of Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom; ⁵NIHR Birmingham Liver Biomedical Research Unit and Centre for Liver Research, University of Birmingham, Birmingham, United Kingdom.
Aim of the study is to assess the incidence of acute kidney injury (AKI) and chronic kidney disease (CKD) after liver transplantation (LT) in DCD…
2016 American Transplant Congress
Metabolomic Profiling of Individuals with Failing Kidney Allograft.
R. Bassi,^1,2 M. Niewczas,³ L. Biancone,⁵ S. Bussolino,⁵ A. Lin,⁴ A. Chandraker,⁶ P. Fiorina.^1,2
¹Nephrology, Boston Children's Hospital, Boston; ²Transplant Medicine, IRCCS San Raffaele Hospital, Milan, Italy; ³Genetics and Epidemiology, Joslin Diabetes Center, Boston; ⁴Radiology, Brigham and Women's Hospital, Boston; ⁵Nephrology and Transplantation, San Giovanni Battista Hospital, Turin, Italy; ⁶Transplantation Research Center, Brigham and Women's Hospital, Boston.
Alteration of certain metabolites may play a role in the pathophysiology of renal allograft disease. To explore metabolome abnormalities in individuals with a failing kidney…
2016 American Transplant Congress
Outcomes of Pediatric en Bloc Kidney (PeB) Grafts After Loss of a Single Kidney.
C. Santhanakrishnan, R. Perez, J. McVicar, J. Sageshima, C. Troppmannn.
Division of Transplantation, Dept of Surgery, Univ of Calif Davis Medical Center, Sacramento, CA.
Background: Transplantation (Tx) of PeB kidney grafts has been shown to result in good long-term outcomes. However, the fate of PeB grafts that suffer loss…