ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal dysfunction"

  • 2022 American Transplant Congress

    On the Circuit: Intra-Operative CRRT in Pediatric Liver Transplant Recipients with Acute Kidney Injury

    E. Blanchette1, M. Chandran2, D. Yoeli3, M. Adams3, M. Bock1

    1Pediatric Nephrology, University of Colorado, Aurora, CO, 2Transplant Pharmacy, University of North Carolina, Raleigh, NC, 3Transplant Surgery, University of Colorado, Aurora, CO

    *Purpose: Acute renal failure is common in pediatric patients undergoing liver transplantation (LT), with an incidence of 17-55%. Fluid, metabolic and acid-base aberrancies are often…
  • 2022 American Transplant Congress

    Daratumumab Therapy Achieves Dialysis Independence in Kidney Transplant Recipients with Resistant Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits

    P. Yenebere, R. Daloul

    The Ohio State University, Columbus, OH

    *Purpose: Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a unique cause for monoclonal gammopathy of renal significance with overall poor prognosis. Patients are frequently…
  • 2022 American Transplant Congress

    Meta-Analysis of the Chronic Exposure to Calcineurin Inhibitors and the Risk for Chronic and End-Stage Kidney Disease in Non-Renal Solid Organ Transplant Recipients

    A. Alvarez Elias1, M. Riedl1, D. Stewart2, A. Ruco3, P. Bobos3, S. Maharaj4, V. Shah5, E. Uleryk6, C. Teoh1, R. Parekh1

    1Hospital for Sick Children, Toronto, ON, Canada, 2Royal Hospital for Children, Glasgow, United Kingdom, 3St. Michael’s Hospital, Toronto, ON, Canada, 4University of Toronto, Toronto, ON, Canada, 5Mount Sinai Hospital, Toronto, ON, Canada, 6E. M. Uleryk Consulting, Toronto, ON, Canada

    *Purpose: Calcineurin inhibitors (CNI) are standard of care immunosuppressants among all solid organ transplant (SOT) recipients, and the most common side effect is nephrotoxicity. There…
  • 2022 American Transplant Congress

    Re-Examining the Optimal Threshold for Donor Derived Cell Free DNA in Renal Allograft Rejection

    H. Murad1, M. Merzkani1, M. Ji1, S. Chang1, A. Malone1, R. Delos Santos1, T. Alhamad2

    1Washington University in St. Louis, St Louis, MO, 2Washington University in St. Louis, Saint Louis, MO

    *Purpose: Due to the invasive nature and potential complications of allograft biopsies, there is an important role for surrogate biomarkers to help identify rejection early,…
  • 2022 American Transplant Congress

    Single-cell Transcriptomic Analysis Of Peripheral Blood Reveals The Disparate Subsets Of Innate Immune Cells In Kidney Transplant Recipient With BK Virus Infection

    H. BAE1, J. Ryu2, J. Jang1, J. Lee1, G. Ko1, H. PARK1, E. Oh3

    1Department of Biomedical Science, Graduate School, College of medicine, The Catholic university of Korea, Seoul, Seoul, Korea, Republic of, 2Department of Laboratory Medicine, College of Medicine, Seoul St. Mary’s hospital, the Catholic University of Korea, seoul, Korea, Republic of, 3Catholic University Department of Laboratory Medicine, Seoul 137-040, Korea, Republic of

    *Purpose: BK virus (BKV) infection is a common problem in kidney transplant recipients receiving immunosuppressive therapy, resulting in a serious complications including BKV-associated nephropathy and…
  • 2022 American Transplant Congress

    Steatosis Following Liver Transplantation for Nonalcoholic Steatohepatitis is Associated with a Higher Rate of Cardiovascular Complications

    W. Alhamoudi1, S. Alqahtani2, K. Bzeizi2, A. Albenmousa2, Y. Saleh2, D. Broering2, S. Alghamdi2

    1Medicine, King Saud University, Riyadh, Saudi Arabia, 2Liver Transplantation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

    *Purpose: Cirrhosis secondary to Nonalcoholic Steatohepatitis (NASH) is projected to become the leading indication for liver transplantation (LT) worldwide. Objectives: to evaluate the prevalence of…
  • 2022 American Transplant Congress

    Characterization of Acute Kidney Injury in Fatty Liver Ischemia Reperfusion Injury

    Z. P. Rokop, W. Zhang, N. Ghosh, A. Das, N. Biswas, C. Sen, C. Kubal

    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: The association between hepatic ischemia reperfusion injury (hIRI) and acute kidney injury (AKI) has been well established. AKI is commonly observed following transplantation of…
  • 2022 American Transplant Congress

    Impact of Belatacept Conversion on Renal Function and Donor Specific Antibodies in Renal Transplant Recipients

    E. R. Brown, K. Cunningham, K. Paplaczyk, C. Dagostino, C. Kane, A. Shetty

    Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Although associated with nephrotoxicity, calcineurin inhibitors (CNI) have historically been the cornerstone of immunosuppression. Belatacept, a co-stimulation blocker, is FDA-approved for de novo use…
  • 2022 American Transplant Congress

    Apoptotic Exosome-Like Vesicles Aggravate Inflammation and Renal Injury After Ischemia-Reperfusion

    I. Kaci1, S. Lan1, H. Kim1, A. Karakeussian Rimbaud1, F. Migneault1, J. Turgeon1, N. Patey2, M. Dieudé1, M. Hébert1

    1Research Centre, Centre hospitalier de l’Université de Montréal, Montreal, QC, Canada, 2Research Centre, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada

    *Purpose: Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) and chronic kidney disease (CKD). Damage to microvascular peritubular capillaries (PTC) is…
  • 2022 American Transplant Congress

    Efficacy and Safety of Angiotensin II Compared to Catecholamine Vasopressors as a First-Line Vasopressor for Perioperative Hypotension in Kidney Transplant Recipients

    G. Urias1, J. Benken1, A. Lichvar2, D. Pierce1, L. Andrews1, K. Dalton3, A. Datta1, H. Nishioka1, E. Benedetti1, S. Benken1

    1University of Illinois at Chicago, Chicago, IL, 2University of California San Diego Health, San Diego, CA, 3St. David's Healthcare, Austin, TX

    *Purpose: Perioperative use of catecholamine vasopressors (CV) in kidney transplantation (KT) have been associated with negative renal outcomes and the development of arrhythmias. A more…
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